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Elayaperumal Manikandan

Bio: Elayaperumal Manikandan is an academic researcher from Thiruvalluvar University. The author has contributed to research in topics: High-resolution transmission electron microscopy & Materials science. The author has an hindex of 42, co-authored 107 publications receiving 4706 citations. Previous affiliations of Elayaperumal Manikandan include Sri Sivasubramaniya Nadar College of Engineering & National Research Foundation of South Africa.


Papers
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Journal ArticleDOI
TL;DR: In this paper, the main physical properties of ZnO nanoparticles synthesized for the first time by a completely green process using Agathosma betulina plant extract as an effective chelating agent are reported.

282 citations

Journal ArticleDOI
TL;DR: The green synthesized CuONPs using R. tuberosa aqueous extract revealed antimicrobial effects against clinical pathogens such as Staphylococcus aureus, Escherichia coli and Klebsiella pneumoniae and could provide a remedy against bacterial pathogens in hospital and industrial environments.
Abstract: Growing concerns over the toxicity of metallic nanoparticles synthesized using physical and chemical techniques seems to be a major hurdle for researchers. Green synthesis of nanoparticles is one of the promising, ecofriendly and safer methods. Utilizing plant sources as reducing agents will replace the use of toxic chemicals for nanoparticle synthesis. Among the various nanoparticles, copper has been theoretically and practically proved for its antimicrobial properties. However, to reduce the risk of copper toxicity, Ruellia tuberosa (R. tuberosa) aqueous extract is used for the synthesis of CuONPs in the present study. Nonetheless, till date no work has been reported on the use of R. tuberosa aqueous extract for the synthesis of CuONPs. In the present study, aqueous extract of R. tuberosa has been used for the synthesis of CuONPs. The synthesis of CuONPs was confirmed by the absorption peak at 327 nm representing the nanorods with an average size of 83.23 nm. Further, the CuONPs revealed antimicrobial effects against clinical pathogens such as Staphylococcus aureus, Escherichia coli and Klebsiella pneumoniae. Embedding CuONPs on cotton fabrics showed bactericidal activity against the bacterial pathogens. In addition, the photocatalytic property of the CuONPs was divulged by their crystal violet (CV) dye degradation potential. Thus, the green synthesized CuONPs using R. tuberosa could provide a remedy against bacterial pathogens in hospital and industrial environments.

224 citations

Journal ArticleDOI
TL;DR: In this paper, the synthesis and the main physical properties of p-type NiO nanoparticles synthesized for the first time by a completely green process using Agathosma betulina plant extract as an effective oxidizing/reducing agent are reported.

223 citations

Journal ArticleDOI
TL;DR: In this article, the structures, morphologies, optical activity and antibacterial properties of Lanthanum (La) doped zinc oxide (ZnO) nanomaterials were investigated by powder X-ray diffraction (XRD), Fourier transform infrared (FT-IR) spectroscopy, High resolution scanning electron microscopy (HR-SEM), Energy dispersive x-ray (EDX), UV-Visible, Photoluminescence (PL) analyzer.

220 citations

Journal ArticleDOI
TL;DR: The biosynthesized silver nanoparticles showed a significant anticancer activity against both MCF-7 and Hep-2 cells compared to Piper nigrum extract which was dose dependent.
Abstract: In the present report, silver nanoparticles were synthesized using Piper nigrum extract for in vitro cytotoxicity efficacy against MCF-7 and HEP-2 cells. The silver nanoparticles (AgNPs) were formed within 20min and after preliminarily confirmation by UV-Visible spectroscopy (strong peak observed at ~441nm), they were characterized by using FT-IR and HR-TEM. The TEM images show spherical shape of biosynthesized AgNPs with particle size in the range 5-40nm while as compositional analysis were observed by EDAX. MTT assays were carried out for cytotoxicity of various concentrations of biosynthesized silver nanoparticles and Piper nigrum extract ranging from 10 to 100μg. The biosynthesized silver nanoparticles showed a significant anticancer activity against both MCF-7 and Hep-2 cells compared to Piper nigrum extract which was dose dependent. Our study thus revealed an excellent application of greenly synthesized silver nanoparticles using Piper nigrum. The study further suggested the potential therapeutic use of these nanoparticles in cancer study.

217 citations


Cited by
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Journal ArticleDOI
TL;DR: This review focused on the latest data regarding the biomedical use of AgNP-based nanostructures, including aspects related to their potential toxicity, unique physiochemical properties, and biofunctional behaviors, discussing herein the intrinsic anti-inflammatory, antibacterial, antiviral, and antifungal activities of silver-based Nanostructure.
Abstract: During the past few years, silver nanoparticles (AgNPs) became one of the most investigated and explored nanotechnology-derived nanostructures, given the fact that nanosilver-based materials proved to have interesting, challenging, and promising characteristics suitable for various biomedical applications. Among modern biomedical potential of AgNPs, tremendous interest is oriented toward the therapeutically enhanced personalized healthcare practice. AgNPs proved to have genuine features and impressive potential for the development of novel antimicrobial agents, drug-delivery formulations, detection and diagnosis platforms, biomaterial and medical device coatings, tissue restoration and regeneration materials, complex healthcare condition strategies, and performance-enhanced therapeutic alternatives. Given the impressive biomedical-related potential applications of AgNPs, impressive efforts were undertaken on understanding the intricate mechanisms of their biological interactions and possible toxic effects. Within this review, we focused on the latest data regarding the biomedical use of AgNP-based nanostructures, including aspects related to their potential toxicity, unique physiochemical properties, and biofunctional behaviors, discussing herein the intrinsic anti-inflammatory, antibacterial, antiviral, and antifungal activities of silver-based nanostructures.

773 citations

Journal ArticleDOI
Ling Zhu1, Wen Zeng1
TL;DR: In this paper, the room-temperature gas sensing properties of ZnO-based gas sensors are comprehensively reviewed, and more attention is particularly paid to the effective strategies that create room temperature gas sensing, mainly including surface modification, additive doping and light activation.
Abstract: Novel gas sensors with high sensing properties, simultaneously operating at room temperature are considerably more attractive owing to their low power consumption, high security and long-term stability. Till date, zinc oxide (ZnO) as semiconducting metal oxide is considered as the promising resistive-type gas sensing material, but elevated operating temperature becomes the bottleneck of its extensive applications in the field of real-time gas monitoring, especially in flammable and explosive gas atmosphere. In this respect, worldwide efforts have been devoted to reducing the operating temperature by means of multiple methods In this communication, room-temperature gas sensing properties of ZnO based gas sensors are comprehensively reviewed. Much more attention is particularly paid to the effective strategies that create room-temperature gas sensing of ZnO based gas sensors, mainly including surface modification, additive doping and light activation. Finally, some perspectives for future investigation on room-temperature gas-sensing materials are discussed as well.

756 citations

Journal ArticleDOI
TL;DR: In this paper, a comprehensive review of the synthesis and characterization methods used for green synthesis of ZnO NPs using different biological sources is presented, including plants, fungus, bacteria, and algae.

669 citations

Journal ArticleDOI
TL;DR: In this article, a green approach for the synthesis of zinc oxide nanoparticles employing aqueous flower extract of Nyctanthes arbor-tristis was presented, and the resulting nanopowder was stored in dried form and was found to be stable after 4 months.

483 citations

Journal ArticleDOI
TL;DR: This review will address biological entities that can be used for the green synthesis of NPs and their prospects for biotechnological applications.
Abstract: The green synthesis of nanoparticles (NPs) using living cells is a promising and novelty tool in bionanotechnology. Chemical and physical methods are used to synthesize NPs; however, biological methods are preferred due to its eco-friendly, clean, safe, cost-effective, easy, and effective sources for high productivity and purity. High pressure or temperature is not required for the green synthesis of NPs, and the use of toxic and hazardous substances and the addition of external reducing, stabilizing, or capping agents are avoided. Intra- or extracellular biosynthesis of NPs can be achieved by numerous biological entities including bacteria, fungi, yeast, algae, actinomycetes, and plant extracts. Recently, numerous methods are used to increase the productivity of nanoparticles with variable size, shape, and stability. The different mechanical, optical, magnetic, and chemical properties of NPs have been related to their shape, size, surface charge, and surface area. Detection and characterization of biosynthesized NPs are conducted using different techniques such as UV-vis spectroscopy, FT-IR, TEM, SEM, AFM, DLS, XRD, zeta potential analyses, etc. NPs synthesized by the green approach can be incorporated into different biotechnological fields as antimicrobial, antitumor, and antioxidant agents; as a control for phytopathogens; and as bioremediative factors, and they are also used in the food and textile industries, in smart agriculture, and in wastewater treatment. This review will address biological entities that can be used for the green synthesis of NPs and their prospects for biotechnological applications.

459 citations