E
Elena A. Govorkova
Researcher at St. Jude Children's Research Hospital
Publications - 141
Citations - 10274
Elena A. Govorkova is an academic researcher from St. Jude Children's Research Hospital. The author has contributed to research in topics: Virus & Influenza A virus subtype H5N1. The author has an hindex of 50, co-authored 133 publications receiving 9637 citations. Previous affiliations of Elena A. Govorkova include World Health Organization & Russian Academy.
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Journal ArticleDOI
Role of domestic ducks in the propagation and biological evolution of highly pathogenic H5N1 influenza viruses in Asia
Diane J. Hulse-Post,K. M. Sturm-Ramirez,Jennifer Humberd,Patrick Seiler,Elena A. Govorkova,Scott Krauss,Christoph Scholtissek,Pilaipan Puthavathana,Chantanee Buranathai,Toan D. Nguyen,Hoang T. Long,T. S. P. Naipospos,Hualan Chen,Trevor M. Ellis,Yi Guan,Joseph S. M. Peiris,Robert G. Webster +16 more
TL;DR: It is shown that these H5N1 viruses are reverting to nonpathogenicity in ducks, suggesting that the duck has become the "Trojan horse" of Asian H 5N1 influenza viruses.
Journal ArticleDOI
Are Ducks Contributing to the Endemicity of Highly Pathogenic H5N1 Influenza Virus in Asia
K. M. Sturm-Ramirez,Diane J. Hulse-Post,Elena A. Govorkova,Jennifer Humberd,Patrick Seiler,Pilaipanl Puthavathana,Chantanee Buranathai,Toan D. Nguyen,A. Chaisingh,Hoang T. Long,T. S. P. Naipospos,Hualan Chen,Trevor M. Ellis,Yi Guan,Yi Guan,Joseph S. M. Peiris,Joseph S. M. Peiris,Robert G. Webster,Robert G. Webster +18 more
TL;DR: Eight virus isolates that were nonpathogenic in ducks replicated and transmitted efficiently to naïve contacts, suggesting that highly pathogenic H5N1 viruses causing minimal signs of disease in ducks can propagate silently and efficiently among domestic and wild ducks in Asia and that they represent a serious threat to human and veterinary public health.
Journal ArticleDOI
Evolution of H5N1 avian influenza viruses in Asia
Jean Thierry Aubin,Saliha Azebi,Amanda Balish,Jill Banks,Niranjan Bhat,Rick A. Bright,Ian Brown,Philippe Buchy,Ana Maria Burguiere,Hua Ian Chen,Peter K.C. Cheng,Nancy J. Cox,Alice Crosier,Aaron Curns,Frédérique Cuvelier,Guohua Deng,Julia Desheva,Stéphanie Desvaux,Nguyen Hong Diep,Ruben O. Donis,Ruben O. Donis,A. R. Douglas,Scott F. Dowell,Nguyen Tien Dung,Lindsay Edwards,Keiji Fukuda,Rebecca Garten,Elena A. Govorkova,Victoria Gregory,Alan W. Hampson,Nguyen Thi Hong Hanh,Scott A. Harper,A. Hay,Erich Hoffmann,Diane J. Hulse,Masaki Imai,Shigeyuki Itamura,Samadhan Jadhao,Patricia Jeannin,Chun Kang,Jackie Katz,Jae Hong Kim,Alexander Klimov,Yong Kuk Kwon,Chang-Won Lee,Phuong Song Lien,Yanbing Li,Wilina Lim,Yi Pu Lin,Stephen Lindstom,La Morris Loftin,Jan Mabry,Le Quynh Mai,Taronna R. Maines,Jean Claude Manuguerra,Masaji Mase,Yumi Matsuoka,Margaret McCarron,Marie-Jo Medina,Doan Nguyen,Ai Ninomiya,Masatsugu Obuchi,Takato Odagiri,Malik Peiris,Michael L. Perdue,Jean Marc Reynes,James Robertson,Claudine Rousseaux,Takehiko Saito,Somchai Sangkitporn,Michael W. Shaw,James Mark Simmerman,Marek J. Slomka,Catherine K. Smith,San Sorn,Erica Spackman,Klaus Stöhr,David L. Suarez,Haan Woo Sung,David E. Swayne,Maryse Tardy-Panit,Masato Tashiro,Pranee Thawatsupha,Terrence M. Tumpey,Timothy M. Uyeki,Phan Van Tu,Sylvie van der Werf,Sirenda Vong,Richard J. Webby,Robert G. Webster,John Wood,Xiyan Xu,Guan Yi,Wenging Zhang +93 more
TL;DR: Human infections were from a virus clade undergoing antigenic drift that showed resistance to adamantanes but sensitivity to neuraminidase inhibitors.
Journal ArticleDOI
H5N1 Influenza — Continuing Evolution and Spread
TL;DR: It would be prudent to develop robust plans for dealing with such a pandemic given the number of cases of H5N1 influenza that have occurred in humans to date and the rate of death of more than 50%, Drs.
Journal ArticleDOI
Lethality to Ferrets of H5N1 Influenza Viruses Isolated from Humans and Poultry in 2004
Elena A. Govorkova,Jerold E. Rehg,Scott Krauss,Hui-Ling Yen,Yi Guan,Malik Peiris,Tien D. Nguyen,Thi H. Hanh,Pilaipanl Puthavathana,Hoang T. Long,Chantanee Buranathai,Wilina Lim,Robert G. Webster,Erich Hoffmann +13 more
TL;DR: In this paper, the authors studied the pathogenicity of four human and nine avian H5N1/04 influenza viruses in ferrets (an excellent model for influenza studies).