E
Eleni Mina
Researcher at Leiden University Medical Center
Publications - 19
Citations - 385
Eleni Mina is an academic researcher from Leiden University Medical Center. The author has contributed to research in topics: Workflow & Huntington's disease. The author has an hindex of 10, co-authored 16 publications receiving 344 citations. Previous affiliations of Eleni Mina include Leiden University.
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Journal ArticleDOI
Using a suite of ontologies for preserving workflow-centric research objects
Khalid Belhajjame,Jun Zhao,Daniel Garijo,Matthew Gamble,Kristina Hettne,Raul Palma,Eleni Mina,Oscar Corcho,Jose Manuel Gomez-Perez,Sean Bechhofer,Graham Klyne,Carole Goble +11 more
TL;DR: A novel approach to the preservation of scientific workflows through the application of research objects-aggregations of data and metadata that enrich the workflow specifications that support the creation of workflow-centric research objects.
Journal ArticleDOI
Integration of targeted metabolomics and transcriptomics identifies deregulation of phosphatidylcholine metabolism in Huntington's disease peripheral blood samples.
Anastasios Mastrokolias,René Pool,René Pool,Eleni Mina,Kristina Hettne,Erik van Duijn,Roos C. van der Mast,Gert-Jan B. van Ommen,Peter A C 't Hoen,Cornelia Prehn,Jerzy Adamski,Willeke M. C. van Roon-Mom +11 more
TL;DR: The notion that phosphatidylcholine metabolism is deregulated in HD blood and that these metabolite alterations are associated with specific gene expression changes is supported.
Proceedings Article
Best practices for workflow design: how to prevent workflow decay
Kristina Hettne,Katy Wolstencroft,Khalid Belhajjame,Carole Goble,Eleni Mina,Harish Dharuri,Lourdes Verdes-Montenegro,Julián Garrido,David De Roure,Marco Roos +9 more
TL;DR: It is argued that good workflow design is a prerequisite for repairing a workflow, or redesigning an equivalent workflow pattern with new components, and the semantic tooling that is being developed in the Workflow4Ever project to support these best practices are presented.
Journal ArticleDOI
Structuring research methods and data with the research object model: genomics workflows as a case study
Kristina Hettne,Harish Dharuri,Jun Zhao,Katherine Wolstencroft,Katherine Wolstencroft,Khalid Belhajjame,Stian Soiland-Reyes,Eleni Mina,Mark Thompson,Don Cruickshank,Lourdes Verdes-Montenegro,Julián Garrido,David De Roure,Oscar Corcho,Graham Klyne,Reinout van Schouwen,Peter A C 't Hoen,Sean Bechhofer,Carole Goble,Marco Roos +19 more
TL;DR: In this paper, a workflow-centric Research Object (RO) model is proposed to aggregate and annotate the resources used in a bioinformatics experiment, allowing to retrieve the conclusions of the experiment in the context of the driving hypothesis, the executed workflows and their input data.
Journal ArticleDOI
Structuring research methods and data with the Research Object model: genomics workflows as a case study
Kristina Hettne,Harish Dharuri,Jun Zhao,Katherine Wolstencroft,Katherine Wolstencroft,Khalid Belhajjame,Stian Soiland-Reyes,Eleni Mina,Mark Thompson,Don Cruickshank,Lourdes Verdes-Montenegro,Julián Garrido,David De Roure,Oscar Corcho,Graham Klyne,Reinout van Schouwen,Peter A C 't Hoen,Sean Bechhofer,Carole Goble,Marco Roos +19 more
TL;DR: Applying a workflow-centric RO model to aggregate and annotate the resources used in a bioinformatics experiment allowed us to retrieve the conclusions of the experiment in the context of the driving hypothesis, the executed workflows and their input data.