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Elizabeth A. Mittendorf
Researcher at Brigham and Women's Hospital
Publications - 467
Citations - 19853
Elizabeth A. Mittendorf is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 60, co-authored 368 publications receiving 14706 citations. Previous affiliations of Elizabeth A. Mittendorf include University of Texas MD Anderson Cancer Center & Harvard University.
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Journal ArticleDOI
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
Sonia A. Melo,Linda B. Luecke,Christoph Kahlert,Agustín F. Fernández,Seth T. Gammon,Judith Kaye,Valerie S. LeBleu,Elizabeth A. Mittendorf,Juergen Weitz,Nuh N. Rahbari,Christoph Reissfelder,Christian Pilarsky,Mario F. Fraga,David Piwnica-Worms,Raghu Kalluri +14 more
TL;DR: GPC1+ crExos may serve as a potential non-invasive diagnostic and screening tool to detect early stages of pancreatic cancer to facilitate possible curative surgical therapy.
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Sentinel Lymph Node Surgery After Neoadjuvant Chemotherapy in Patients With Node-Positive Breast Cancer: The ACOSOG Z1071 (Alliance) Clinical Trial
Judy C. Boughey,Vera J. Suman,Elizabeth A. Mittendorf,Gretchen M. Ahrendt,Lee G. Wilke,Bret Taback,A. Marilyn Leitch,Henry Mark Kuerer,Monet Bowling,Teresa S. Flippo-Morton,David R. Byrd,David W. Ollila,Thomas B. Julian,Sarah A. McLaughlin,Linda M. McCall,W. Fraser Symmans,Huong T. Le-Petross,Bruce G. Haffty,Thomas A. Buchholz,Heidi Nelson,Kelly K. Hunt +20 more
TL;DR: The application of SLN surgery for staging the axilla following chemotherapy for women who initially had node-positive cN1 breast cancer is unclear because of high false-negative results reported in previous studies as mentioned in this paper.
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PD-L1 Expression in Triple-Negative Breast Cancer
Elizabeth A. Mittendorf,Anne V. Philips,Funda Meric-Bernstam,Na Qiao,Yun Wu,Susan M. Harrington,Xiaoping Su,Ying Wang,Ana M. Gonzalez-Angulo,Argun Akcakanat,Akhil Chawla,Michael Curran,Patrick Hwu,Padmanee Sharma,Jennifer K. Litton,Jeffrey J. Molldrem,Gheath Alatrash +16 more
TL;DR: Using tissue microarrays containing 105 triple-negative breast cancer specimens, Mittendorf and colleagues show that 20% of the TNBC specimens express PD-L1, half have lost PTEN, and inhibitors of PI3K pathway decrease PD- l1 expression, providing a rationale for therapeutic targeting of PD- L1 for TNBC.
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Improved Axillary Evaluation Following Neoadjuvant Therapy for Patients With Node-Positive Breast Cancer Using Selective Evaluation of Clipped Nodes: Implementation of Targeted Axillary Dissection
Abigail S. Caudle,Wei T. Yang,Savitri Krishnamurthy,Elizabeth A. Mittendorf,Dalliah M. Black,Michael Z. Gilcrease,Isabelle Bedrosian,Brian P. Hobbs,Sarah M. DeSnyder,Rosa F. Hwang,Beatriz E. Adrada,Simona F. Shaitelman,Mariana Chavez-MacGregor,Benjamin Smith,Rosalind P. Candelaria,Gildy Babiera,Basak E. Dogan,Lumarie Santiago,Kelly K. Hunt,Henry Mark Kuerer +19 more
TL;DR: Marking nodes with biopsy-confirmed metastatic disease allows for selective removal and improves pathologic evaluation for residual nodal disease after chemotherapy, as determined in patients undergoing complete axillary lymphadenectomy.
Journal ArticleDOI
Breast Cancer—Major changes in the American Joint Committee on Cancer eighth edition cancer staging manual
Armando E. Giuliano,James L. Connolly,Stephen B. Edge,Elizabeth A. Mittendorf,Hope S. Rugo,Lawrence J. Solin,Donald L. Weaver,David J. Winchester,Gabriel N. Hortobagyi +8 more
TL;DR: The American Joint Commission of Cancer (AJCC) published the 8th edition of the primary tumor, lymph node, and metastasis (TNM) classification for breast cancer as discussed by the authors.