E
Elizabeth M. Wilson
Researcher at University of North Carolina at Chapel Hill
Publications - 198
Citations - 26097
Elizabeth M. Wilson is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Androgen receptor & Androgen. The author has an hindex of 75, co-authored 195 publications receiving 25126 citations. Previous affiliations of Elizabeth M. Wilson include University at Buffalo.
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Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy.
TL;DR: It is concluded that enlargement of the CAG repeat in the androgen receptor gene is probably the cause of X-LINKED spinal and bulbar muscular atrophy.
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Persistent DDT metabolite p,p'-DDE is a potent androgen receptor antagonist.
William R. Kelce,Stone Cr,Susan C. Laws,Leon Earl Gray,Jon A. Kemppainen,Elizabeth M. Wilson +5 more
TL;DR: It is reported that the major and persistent DDT metabolite,P,P′-DDE (l,l-dichloro-2,2-bis(P- chlorophenyl)ethylene), has little ability to bind the oestrogen receptor, but inhibits androgen binding to the androgen receptor.
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Androgen receptor defects : Historical, clinical, and molecular perspectives
Charmian A. Quigley,Alessandra De Bellis,Keith B. Marschke,Mostafa K. El-Awady,Elizabeth M. Wilson,Frank S. French +5 more
TL;DR: AIS is an archetypal example of a hormone resistance disorder; however, due to defective androgen receptor (AR1) function, there is loss of target organ response to the hormone, and the effects of androgens are reduced or absent.
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Cloning of human androgen receptor complementary DNA and localization to the X chromosome.
Dennis B. Lubahn,David R. Joseph,Patrick Sullivan,Huntington F. Willard,Frank S. French,Elizabeth M. Wilson +5 more
TL;DR: The deduced amino acid sequence of AR within the DNA-binding domain has highest sequence identity with the progesterone receptor.
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The Androgen Axis in Recurrent Prostate Cancer
James L. Mohler,Christopher W. Gregory,O. Harris Ford,Desok Kim,Catharina M. Weaver,Peter Petrusz,Elizabeth M. Wilson,Frank S. French +7 more
TL;DR: Novel therapies for recurrent prostate cancer should target androgen receptor directly and prevent the formation of androgens within prostate cancer tissue at levels sufficient to activate androgenceptor.