E
Elizabeth R. Oldham
Researcher at Schering-Plough
Publications - 4
Citations - 3802
Elizabeth R. Oldham is an academic researcher from Schering-Plough. The author has contributed to research in topics: Interleukin-21 receptor & Interleukin-1 Receptor-Like 1 Protein. The author has an hindex of 4, co-authored 4 publications receiving 3462 citations.
Papers
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Journal ArticleDOI
IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines
Jochen Schmitz,Alexander Owyang,Elizabeth R. Oldham,Yaoli Song,Erin Murphy,Terril K. McClanahan,Gerard Zurawski,Mehrdad M. Moshrefi,Jinzhong Qin,Xiaoxia Li,Daniel M. Gorman,J. Fernando Bazan,Robert A. Kastelein +12 more
TL;DR: A member of theIL-1 family, IL-33, which mediates its biological effects via IL-1 receptor ST 2, activates NF-kappaB and MAP kinases, and drives production of T(H)2-associated cytokines from in vitro polarized T( H)2 cells is reported.
Journal ArticleDOI
IL-1 Receptor Accessory Protein and ST2 Comprise the IL-33 Receptor Complex
Alissa A. Chackerian,Elizabeth R. Oldham,Erin Murphy,Jochen Schmitz,Stefan Pflanz,Robert A. Kastelein +5 more
TL;DR: It is demonstrated that IL-33 and ST2 form a complex with IL-1R accessory protein (IL-1RAcP), a signaling receptor subunit that is also a member of the IL- 1R complex.
Patent
Use of agonists or antagonists of mip-3a in therapy
Christophe Caux,Marie-Caroline Dieu-Nosjean,Bernhard Homey,Elizabeth R. Oldham,Albert Zlotnik +4 more
TL;DR: In this paper, the authors make use of the fact that the MIP-3α chemokine is specifically capable of inducing migration of a skin cell subset, and use it in dermatological and related applications.
Patent
Agonists or antagonists of cutaneous t cell-attracting chemokine (ctack) or vasoactive intestinal contractor (vic) chemokines
Wei Wang,Elizabeth R. Oldham,Hortensia Soto,Ying Lui,Susan A. Hudak,Bernhard Homey,Janine Morales,Sirid-Aimee Kellermann,Leslie M. Mcevoy,Albert Zlotnik +9 more
TL;DR: In this paper, Agonists or antagonists of CTACK or Vic chemokines, and various methods of use in dermatological and related applications are provided, in particular, the method makes use of fact that the CTACK/Vic chemokine are specifically capable of inducing movement of a skin cell subset.