E
Elizabeth W. Pugh
Researcher at Johns Hopkins University School of Medicine
Publications - 37
Citations - 6573
Elizabeth W. Pugh is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Genome-wide association study & Single-nucleotide polymorphism. The author has an hindex of 25, co-authored 37 publications receiving 5875 citations. Previous affiliations of Elizabeth W. Pugh include National Institutes of Health & Johns Hopkins University.
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Journal ArticleDOI
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.
Laura J. Scott,Karen L. Mohlke,Lori L. Bonnycastle,Cristen J. Willer,Yun Li,William L. Duren,Michael R. Erdos,Heather M. Stringham,Peter S. Chines,Anne U. Jackson,Ludmila Prokunina-Olsson,Chia-Jen Ding,Amy J. Swift,Narisu Narisu,Tianle Hu,Randall Pruim,Rui Xiao,Xiao-Yi Li,Karen N. Conneely,Nancy Riebow,Andrew G. Sprau,Maurine Tong,Peggy P. White,Kurt N. Hetrick,Michael W. Barnhart,Craig W. Bark,Janet L. Goldstein,Lee Watkins,Fang Xiang,Jouko Saramies,Thomas A. Buchanan,Richard M. Watanabe,Timo T. Valle,Leena Kinnunen,Gonçalo R. Abecasis,Elizabeth W. Pugh,Kimberly F. Doheny,Richard N. Bergman,Jaakko Tuomilehto,Francis S. Collins,Michael Boehnke +40 more
TL;DR: The number of T2D loci now confidently identified to at least 10 is confirmed, and it is confirmed that variants near TCF7L2, SLC30A8, HHEX, FTO, PPARG, and KCNJ11 are associated with T1D risk.
Journal ArticleDOI
Association analysis identifies 65 new breast cancer risk loci
Kyriaki Michailidou,Kyriaki Michailidou,Sara Lindström,Sara Lindström,Joe Dennis,Jonathan Beesley,Shirley Hui,Siddhartha Kar,Audrey Lemaçon,Penny Soucy,Dylan M. Glubb,Asha Rostamianfar,Manjeet K. Bolla,Qin Wang,Jonathan Tyrer,Ed Dicks,Andy C. H. Lee,Zhaoming Wang,Jamie Allen,Renske Keeman,Ursula Eilber,Juliet D. French,Xiaoqing Chen,Laura Fachal,Karen McCue,Amy E. McCart Reed,Maya Ghoussaini,Jason S. Carroll,Xia Jiang,Hilary K. Finucane,Hilary K. Finucane,Marcia Adams,Muriel A. Adank,Habibul Ahsan,Kristiina Aittomäki,Hoda Anton-Culver,Natalia Antonenkova,Volker Arndt,Kristan J. Aronson,Banu Arun,Paul L. Auer,Paul L. Auer,Francois Bacot,Myrto Barrdahl,Caroline Baynes,Matthias W. Beckmann,Sabine Behrens,Javier Benitez,Marina Bermisheva,Leslie Bernstein,Carl Blomqvist,Natalia Bogdanova,Stig E. Bojesen,Stig E. Bojesen,Bernardo Bonanni,Anne Lise Børresen-Dale,Judith S. Brand,Hiltrud Brauch,Hiltrud Brauch,Hiltrud Brauch,Paul Brennan,Hermann Brenner,Louise A. Brinton,Per Broberg,Ian W. Brock,Annegien Broeks,Angela Brooks-Wilson,Angela Brooks-Wilson,Sara Y. Brucker,Thomas Brüning,Barbara Burwinkel,Barbara Burwinkel,Katja Butterbach,Qiuyin Cai,Hui Cai,Trinidad Caldés,Federico Canzian,Angel Carracedo,Brian D. Carter,Jose E. Castelao,Tsun Leung Chan,Tongguang Cheng,Kee Seng Chia,Ji Yeob Choi,Hans Christiansen,Christine L. Clarke,Margriet Collée,Don M. Conroy,Emilie Cordina-Duverger,Sten Cornelissen,David G. Cox,David G. Cox,Angela Cox,Simon S. Cross,Julie M. Cunningham,Kamila Czene,Mary B. Daly,Peter Devilee,Kimberly F. Doheny,Thilo Dörk,Isabel dos-Santos-Silva,Martine Dumont,Lorraine Durcan,Miriam Dwek,Diana Eccles,Arif B. Ekici,A. Heather Eliassen,A. Heather Eliassen,Carolina Ellberg,Mingajeva Elvira,Christoph Engel,Mikael Eriksson,Peter A. Fasching,Peter A. Fasching,Jonine D. Figueroa,Dieter Flesch-Janys,Olivia Fletcher,Henrik Flyger,Lin Fritschi,Valerie Gaborieau,Marike Gabrielson,Manuela Gago-Dominguez,Yu Tang Gao,Susan M. Gapstur,José A. García-Sáenz,Mia M. Gaudet,Vassilios Georgoulias,Graham G. Giles,Graham G. Giles,Gord Glendon,Mark S. Goldberg,David E. Goldgar,Anna González-Neira,Grethe I. Grenaker Alnæs,Mervi Grip,Jacek Gronwald,Anne Grundy,Pascal Guénel,Lothar Haeberle,Eric Hahnen,Christopher A. Haiman,Niclas Håkansson,Ute Hamann,N Hamel,Susan E. Hankinson,Patricia Harrington,Steven N. Hart,Jaana M. Hartikainen,Mikael Hartman,Mikael Hartman,Alexander Hein,Jane Heyworth,Belynda Hicks,Peter Hillemanns,Dona N. Ho,Antoinette Hollestelle,Maartje J. Hooning,Robert N. Hoover,John L. Hopper,Ming-Feng Hou,Chia-Ni Hsiung,Guanmengqian Huang,Keith Humphreys,Junko Ishiguro,Hidemi Ito,Motoki Iwasaki,Hiroji Iwata,Anna Jakubowska,Wolfgang Janni,Esther M. John,Esther M. John,Nichola Johnson,Kristine Jones,Michael Jones,Arja Jukkola-Vuorinen,Rudolf Kaaks,Maria Kabisch,Katarzyna Kaczmarek,Daehee Kang,Daehee Kang,Yoshio Kasuga,Michael J. Kerin,Sofia Khan,Elza Khusnutdinova,Elza Khusnutdinova,Johanna I. Kiiski,Sung-Won Kim,Julia A. Knight,Julia A. Knight,Veli-Matti Kosma,Vessela N. Kristensen,Vessela N. Kristensen,Ute Krüger,Ava Kwong,Diether Lambrechts,Loic Le Marchand,Eunjung Lee,Min Hyuk Lee,Jong Won Lee,Chuen Neng Lee,Flavio Lejbkowicz,Jingmei Li,Jenna Lilyquist,Annika Lindblom,Jolanta Lissowska,Wing-Yee Lo,Wing-Yee Lo,Sibylle Loibl,Jirong Long,Artitaya Lophatananon,Artitaya Lophatananon,Jan Lubinski,Craig Luccarini,Michael P. Lux,Edmond S. K. Ma,Robert J. MacInnis,Robert J. MacInnis,Tom Maishman,Enes Makalic,Kathleen E. Malone,Ivana Maleva Kostovska,Arto Mannermaa,Siranoush Manoukian,JoAnn E. Manson,JoAnn E. Manson,Sara Margolin,Shivaani Mariapun,Maria Elena Martinez,Keitaro Matsuo,Dimitrios Mavroudis,James McKay,Catriona McLean,Hanne Meijers-Heijboer,Alfons Meindl,Primitiva Menéndez,Usha Menon,J.-P. Meyer,Hui Miao,Nicola Miller,Nur Aishah Taib,Kenneth Muir,Kenneth Muir,Anna Marie Mulligan,Anna Marie Mulligan,Claire Mulot,Susan L. Neuhausen,Heli Nevanlinna,Patrick Neven,Sune F. Nielsen,Dong-Young Noh,Børge G. Nordestgaard,Børge G. Nordestgaard,Aaron D. Norman,Olufunmilayo I. Olopade,Janet E. Olson,Håkan Olsson,Curtis Olswold,Nick Orr,V. Shane Pankratz,Sue K. Park,Sue K. Park,Tjoung-Won Park-Simon,Rachel Lloyd,Jose Ignacio Arias Perez,Paolo Peterlongo,Julian Peto,Kelly-Anne Phillips,Mila Pinchev,Dijana Plaseska-Karanfilska,Ross L. Prentice,Nadege Presneau,Darya Prokofyeva,Elizabeth W. Pugh,Katri Pylkäs,Brigitte Rack,Paolo Radice,Nazneen Rahman,Gadi Rennert,Hedy S. Rennert,Valerie Rhenius,Atocha Romero,Jane Romm,Kathryn J. Ruddy,Thomas Rüdiger,Anja Rudolph,Matthias Ruebner,Emiel J. Th. Rutgers,Emmanouil Saloustros,Dale P. Sandler,Suleeporn Sangrajrang,Elinor J. Sawyer,Daniel F. Schmidt,Rita K. Schmutzler,Andreas Schneeweiss,Minouk J. Schoemaker,Fredrick R. Schumacher,Peter Schürmann,Rodney J. Scott,Rodney J. Scott,Christopher G. Scott,Sheila Seal,Caroline Seynaeve,Mitul Shah,Priyanka Sharma,Chen-Yang Shen,Chen-Yang Shen,Grace Sheng,Mark E. Sherman,Martha J. Shrubsole,Xiao-Ou Shu,Ann Smeets,Christof Sohn,Melissa C. Southey,John J. Spinelli,John J. Spinelli,Christa Stegmaier,Sarah Stewart-Brown,Jennifer Stone,Jennifer Stone,Daniel O. Stram,Harald Surowy,Harald Surowy,Anthony J. Swerdlow,Rulla M. Tamimi,Rulla M. Tamimi,Jack A. Taylor,Maria Tengström,Soo Hwang Teo,Mary Beth Terry,Daniel C. Tessier,Somchai Thanasitthichai,Kathrin Thöne,Rob A. E. M. Tollenaar,Ian Tomlinson,Ling Tong,Diana Torres,Diana Torres,Thérèse Truong,Chiu-Chen Tseng,Shoichiro Tsugane,Hans-Ulrich Ulmer,Giske Ursin,Michael Untch,Celine M. Vachon,Christi J. van Asperen,David Van Den Berg,Ans M.W. van den Ouweland,Lizet E. van der Kolk,Rob B. van der Luijt,Daniel Vincent,Jason Vollenweider,Quinten Waisfisz,Shan Wang-Gohrke,Clarice R. Weinberg,Camilla Wendt,Alice S. Whittemore,Hans Wildiers,Walter C. Willett,Robert Winqvist,Alicja Wolk,Anna H. Wu,Lucy Xia,Taiki Yamaji,Xiaohong R. Yang,Cheng Har Yip,Keun-Young Yoo,Jyh-Cherng Yu,Wei Zheng,Ying Zheng,Bin Zhu,Argyrios Ziogas,Elad Ziv,Sunil R. Lakhani,Sunil R. Lakhani,Antonis C. Antoniou,Arnaud Droit,Irene L. Andrulis,Irene L. Andrulis,Christopher I. Amos,Fergus J. Couch,Paul D.P. Pharoah,Jenny Chang-Claude,Jenny Chang-Claude,Per Hall,David J. Hunter,Roger L. Milne,Roger L. Milne,Montserrat Garcia-Closas,Marjanka K. Schmidt,Stephen J. Chanock,Alison M. Dunning,Stacey L. Edwards,Gary D. Bader,Georgia Chenevix-Trench,Jacques Simard,Peter Kraft,Douglas F. Easton +396 more
TL;DR: A genome-wide association study of breast cancer in 122,977 cases and 105,974 controls of European ancestry and 14,068 cases and 13,104 controls of East Asian ancestry finds that heritability of Breast cancer due to all single-nucleotide polymorphisms in regulatory features was 2–5-fold enriched relative to the genome- wide average.
Journal ArticleDOI
Genomewide association study for susceptibility genes contributing to familial Parkinson disease.
Nathan Pankratz,Jemma B. Wilk,Jeanne C. Latourelle,Anita L. DeStefano,Cheryl Halter,Elizabeth W. Pugh,Kimberly F. Doheny,James F. Gusella,William C. Nichols,Tatiana Foroud,Richard H. Myers +10 more
TL;DR: The first genomewide association study in familial Parkinson disease has performed, suggesting the identification of new susceptibility alleles for PD in the GAK/DGKQ region, and providing further support for the role of SNCA and MAPT in PD susceptibility.
Journal ArticleDOI
Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer
Catherine M. Phelan,Karoline Kuchenbaecker,Karoline Kuchenbaecker,Jonathan Tyrer,Siddhartha Kar,Kate Lawrenson,Stacey J. Winham,Joe Dennis,Ailith Pirie,Marjorie J. Riggan,Ganna Chornokur,Madalene Earp,Paulo C Lyra,Janet M. Lee,Simon G. Coetzee,Jonathan Beesley,Lesley McGuffog,Penny Soucy,Ed Dicks,Andrew Lee,Daniel Barrowdale,Julie Lecarpentier,Goska Leslie,Cora M. Aalfs,Katja K.H. Aben,Marcia Adams,Julian Adlard,Irene L. Andrulis,Irene L. Andrulis,Hoda Anton-Culver,Natalia Antonenkova,Gerasimos Aravantinos,Norbert Arnold,Banu Arun,Brita Arver,Jacopo Azzollini,Judith Balmaña,Susana Banerjee,Laure Barjhoux,Rosa B. Barkardottir,Yukie Bean,Matthias W. Beckmann,Alicia Beeghly-Fadiel,Javier Benitez,Marina Bermisheva,Marcus Q. Bernardini,Michael J. Birrer,Line Bjørge,Line Bjørge,Amanda Black,Kenneth Blankstein,Marinus J. Blok,Clara Bodelon,Natalia Bogdanova,Anders Bojesen,Bernardo Bonanni,Åke Borg,Angela R. Bradbury,James D. Brenton,Carole Brewer,Louise A. Brinton,Per Broberg,Angela Brooks-Wilson,Fiona Bruinsma,Joan Brunet,Bruno Buecher,Ralf Bützow,Saundra S. Buys,Trinidad Caldés,Maria A. Caligo,Ian G. Campbell,Ian G. Campbell,Rikki Cannioto,Michael E. Carney,Terence Cescon,Salina B. Chan,Jenny Chang-Claude,Jenny Chang-Claude,Stephen J. Chanock,Xiaoqing Chen,Yoke-Eng Chiew,Yoke-Eng Chiew,Jocelyne Chiquette,Wendy K. Chung,Kathleen Claes,Thomas Conner,Linda S. Cook,Jackie Cook,Daniel W. Cramer,Julie M. Cunningham,Aimee A D'Aloisio,Mary B. Daly,Francesca Damiola,Sakaeva Dina Damirovna,Agnieszka Dansonka-Mieszkowska,Fanny Dao,Rosemarie Davidson,Anna deFazio,Anna deFazio,Capucine Delnatte,Kimberly F. Doheny,Orland Diez,Yuan Chun Ding,Jennifer A. Doherty,Susan M. Domchek,Cecilia M. Dorfling,Thilo Dörk,Laure Dossus,Mercedes Durán,Matthias Dürst,Bernd Dworniczak,Diana Eccles,Todd L. Edwards,Ros Eeles,Ursula Eilber,Bent Ejlertsen,Arif B. Ekici,Steve Ellis,Mingajeva Elvira,Kevin H. Eng,Christoph Engel,D. Gareth Evans,Peter A. Fasching,Peter A. Fasching,Sarah E. Ferguson,Sandra Fert Ferrer,James M. Flanagan,Zachary C. Fogarty,Renée T. Fortner,Florentia Fostira,William D. Foulkes,George Fountzilas,Brooke L. Fridley,Tara M. Friebel,Eitan Friedman,Eitan Friedman,Debra Frost,Patricia A. Ganz,Judy Garber,María Josefa Mosteiro García,Vanesa García-Barberán,Andrea Gehrig,Aleksandra Gentry-Maharaj,Anne-Marie Gerdes,Graham G. Giles,Graham G. Giles,Graham G. Giles,Rosalind Glasspool,Gord Glendon,Andrew K. Godwin,David E. Goldgar,Teodora Goranova,Martin Gore,Mark H. Greene,Jacek Gronwald,Stephen B. Gruber,Eric Hahnen,Christopher A. Haiman,Niclas Håkansson,Ute Hamann,Thomas Hansen,Patricia Harrington,Holly R. Harris,Jan Hauke,Alexander Hein,Alex Henderson,Michelle A.T. Hildebrandt,Peter Hillemanns,Shirley Hodgson,Claus Høgdall,Estrid Høgdall,Frans B. L. Hogervorst,Helene Holland,Maartje J. Hooning,Karen Hosking,Ruea-Yea Huang,Peter J. Hulick,Jillian Hung,Jillian Hung,David J. Hunter,David G. Huntsman,Tomasz Huzarski,Evgeny N. Imyanitov,Claudine Isaacs,Edwin S. Iversen,Louise Izatt,Angel Izquierdo,Anna Jakubowska,Paul A. James,Paul A. James,Ramunas Janavicius,Mats Jernetz,Allan Jensen,Uffe Birk Jensen,Esther M. John,Sharon E. Johnatty,Michael Jones,Päivi Kannisto,Beth Y. Karlan,Anthony N. Karnezis,Karin Kast,Catherine J. Kennedy,Catherine J. Kennedy,Elza Khusnutdinova,Lambertus A. Kiemeney,Johanna I. Kiiski,Sung-Won Kim,Susanne K. Kjaer,Martin Köbel,Reidun K. Kopperud,Reidun K. Kopperud,Torben A Kruse,Jolanta Kupryjanczyk,Ava Kwong,Yael Laitman,Yael Laitman,Diether Lambrechts,Nerea Larrañaga,Melissa C. Larson,Conxi Lázaro,Nhu D. Le,Loic Le Marchand,Jong Won Lee,Shashikant Lele,Arto Leminen,Dominique Leroux,Jenny Lester,Fabienne Lesueur,Fabienne Lesueur,Douglas A. Levine,Dong Liang,Clemens Liebrich,Jenna Lilyquist,Loren Lipworth,Jolanta Lissowska,Karen H. Lu,Jan Lubinński,Craig Luccarini,Lene Lundvall,Phuong L. Mai,Gustavo Mendoza-Fandiño,Siranoush Manoukian,Leon F.A.G. Massuger,Taymaa May,Sylvie Mazoyer,Jessica N. McAlpine,Valerie McGuire,John R. McLaughlin,Iain A. McNeish,Hanne Meijers-Heijboer,Alfons Meindl,Usha Menon,Arjen R. Mensenkamp,Melissa A. Merritt,Roger L. Milne,Roger L. Milne,Gillian Mitchell,Gillian Mitchell,Francesmary Modugno,Joanna Moes-Sosnowska,Melissa Moffitt,Marco Montagna,Kirsten B. Moysich,Anna Marie Mulligan,Anna Marie Mulligan,Jacob Musinsky,Katherine L. Nathanson,Lotte Nedergaard,Roberta B. Ness,Susan L. Neuhausen,Heli Nevanlinna,Dieter Niederacher,Robert L. Nussbaum,Kunle Odunsi,Edith Olah,Olufunmilayo I. Olopade,Håkan Olsson,Curtis Olswold,David M. O'Malley,Kai-ren Ong,N. Charlotte Onland-Moret,Nick Orr,Sandra Orsulic,Ana Osorio,Domenico Palli,Laura Papi,Tjoung-Won Park-Simon,James Paul,Celeste Leigh Pearce,Celeste Leigh Pearce,Inge Søkilde Pedersen,Petra H.M. Peeters,Bernard Peissel,Ana Peixoto,Tanja Pejovic,Liisa M. Pelttari,Jennifer B. Permuth,Paolo Peterlongo,Lidia Pezzani,Georg Pfeiler,Kelly-Anne Phillips,Kelly-Anne Phillips,Marion Piedmonte,Malcolm C. Pike,Malcolm C. Pike,Anna M. Piskorz,Samantha Poblete,Timea Pocza,Elizabeth M. Poole,Bruce Poppe,Mary Porteous,Fabienne Prieur,Darya Prokofyeva,Elizabeth W. Pugh,Miquel Angel Pujana,Pascal Pujol,Paolo Radice,Johanna Rantala,Christine Rappaport-Fuerhauser,Gad Rennert,Kerstin Rhiem,Patricia Rice,Andrea L. Richardson,Mark E. Robson,Gustavo C. Rodriguez,Cristina Rodríguez-Antona,Jane Romm,Matti A. Rookus,Mary Anne Rossing,Joseph H. Rothstein,Anja Rudolph,Ingo B. Runnebaum,Helga B. Salvesen,Helga B. Salvesen,Dale P. Sandler,Minouk J. Schoemaker,Leigha Senter,V. Wendy Setiawan,Gianluca Severi,Priyanka Sharma,Tameka Shelford,Nadeem Siddiqui,Lucy Side,Weiva Sieh,Christian F. Singer,Hagay Sobol,Honglin Song,Melissa C. Southey,Amanda B. Spurdle,Zsofia K. Stadler,Doris Steinemann,Dominique Stoppa-Lyonnet,Lara E. Sucheston-Campbell,Grzegorz Sukiennicki,Rebecca Sutphen,Christian Sutter,Anthony J. Swerdlow,Anthony J. Swerdlow,Csilla Szabo,Lukasz Szafron,Yen Y. Tan,Jack A. Taylor,Muy-Kheng Tea,Manuel R. Teixeira,Soo Hwang Teo,Kathryn L. Terry,Kathryn L. Terry,Pamela J. Thompson,Liv Cecilie Vestrheim Thomsen,Liv Cecilie Vestrheim Thomsen,Darcy L. Thull,Laima Tihomirova,Anna V. Tinker,Marc Tischkowitz,Silvia Tognazzo,Amanda E. Toland,Alicia A. Tone,Britton Trabert,Ruth C. Travis,Antonia Trichopoulou,Nadine Tung,Shelley S. Tworoger,Shelley S. Tworoger,Anne M. van Altena,David Van Den Berg,Annemarie H. van der Hout,Rob B. van der Luijt,Mattias Van Heetvelde,Els Van Nieuwenhuysen,Elizabeth J. van Rensburg,Adriaan Vanderstichele,Raymonda Varon-Mateeva,Ana Vega,Digna R. Velez Edwards,Digna R. Velez Edwards,Ignace Vergote,Robert A. Vierkant,Joseph Vijai,Athanassios Vratimos,Lisa Walker,Christine Walsh,Dorothea Wand,Shan Wang-Gohrke,Barbara Wappenschmidt,Penelope M. Webb,Clarice R. Weinberg,Jeffrey N. Weitzel,Nicolas Wentzensen,Alice S. Whittemore,Juul T. Wijnen,Lynne R. Wilkens,Alicja Wolk,Michelle M.M. Woo,Xifeng Wu,Anna H. Wu,Hannah P. Yang,Drakoulis Yannoukakos,Argyrios Ziogas,Kristin K. Zorn,Steven A. Narod,Douglas F. Easton,Christopher I. Amos,Joellen M. Schildkraut,Susan J. Ramus,Susan J. Ramus,Laura Ottini,Marc T. Goodman,Sue K. Park,Linda E. Kelemen,Harvey A. Risch,Mads Thomassen,Kenneth Offit,Jacques Simard,Rita K. Schmutzler,Dennis J. Hazelett,Alvaro N.A. Monteiro,Fergus J. Couch,Andrew Berchuck,Georgia Chenevix-Trench,Ellen L. Goode,Thomas A. Sellers,Simon A. Gayther,Antonis C. Antoniou,Paul D.P. Pharoah +443 more
TL;DR: Integrated analyses of genes and regulatory biofeatures at each locus predicted candidate susceptibility genes, including OBFC1, a new candidate susceptibility gene for low-grade and borderline serous EOC.
Journal ArticleDOI
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.
Roger L. Milne,Roger L. Milne,Karoline Kuchenbaecker,Karoline Kuchenbaecker,Kyriaki Michailidou,Kyriaki Michailidou,Jonathan Beesley,Siddhartha Kar,Sara Lindström,Sara Lindström,Shirley Hui,Audrey Lemaçon,Penny Soucy,Joe Dennis,Xia Jiang,Asha Rostamianfar,Hilary K. Finucane,Hilary K. Finucane,Manjeet K. Bolla,Lesley McGuffog,Qin Wang,Cora M. Aalfs,Marcia Adams,Julian Adlard,Simona Agata,Shahana Ahmed,Habibul Ahsan,Kristiina Aittomäki,Fares Al-Ejeh,Jamie Allen,Christine B. Ambrosone,Christopher I. Amos,Irene L. Andrulis,Irene L. Andrulis,Hoda Anton-Culver,Natalia Antonenkova,Volker Arndt,Norbert Arnold,Kristan J. Aronson,Bernd Auber,Paul L. Auer,Paul L. Auer,Margreet G. E. M. Ausems,Jacopo Azzollini,Francois Bacot,Judith Balmaña,Monica Barile,Laure Barjhoux,Rosa B. Barkardottir,Myrto Barrdahl,Daniel R. Barnes,Daniel Barrowdale,Caroline Baynes,Matthias W. Beckmann,Javier Benitez,Marina Bermisheva,Leslie Bernstein,Yves-Jean Bignon,Kathleen R. Blazer,Marinus J. Blok,Carl Blomqvist,William J. Blot,Kristie Bobolis,Bram Boeckx,Natalia Bogdanova,Anders Bojesen,Stig E. Bojesen,Stig E. Bojesen,Bernardo Bonanni,Anne Lise Børresen-Dale,Aniko Bozsik,Angela R. Bradbury,Judith S. Brand,Hiltrud Brauch,Hiltrud Brauch,Hiltrud Brauch,Hermann Brenner,Brigitte Bressac-de Paillerets,Carole Brewer,Louise A. Brinton,Per Broberg,Angela Brooks-Wilson,Angela Brooks-Wilson,Joan Brunet,Thomas Brüning,Barbara Burwinkel,Barbara Burwinkel,Saundra S. Buys,Jinyoung Byun,Qiuyin Cai,Trinidad Caldés,Maria A. Caligo,Ian G. Campbell,Ian G. Campbell,Federico Canzian,Olivier Caron,Angel Carracedo,Brian D. Carter,J. Esteban Castelao,Laurent Castera,Virginie Caux-Moncoutier,Salina B. Chan,Jenny Chang-Claude,Jenny Chang-Claude,Stephen J. Chanock,Xiaoqing Chen,Tongguang Cheng,Jocelyne Chiquette,Hans Christiansen,Kathleen Claes,Christine L. Clarke,Thomas Conner,Don M. Conroy,Jackie Cook,Emilie Cordina-Duverger,Sten Cornelissen,Isabelle Coupier,Angela Cox,David G. Cox,David G. Cox,Simon S. Cross,Katarina Cuk,Julie M. Cunningham,Kamila Czene,Mary B. Daly,Francesca Damiola,Hatef Darabi,Rosemarie Davidson,Kim De Leeneer,Peter Devilee,Ed Dicks,Orland Diez,Yuan Chun Ding,Nina Ditsch,Kimberly F. Doheny,Susan M. Domchek,Cecilia M. Dorfling,Thilo Dörk,Isabel dos-Santos-Silva,Stéphane Dubois,Pierre Antoine Dugué,Pierre Antoine Dugué,Martine Dumont,Alison M. Dunning,Lorraine Durcan,Miriam Dwek,Bernd Dworniczak,Diana Eccles,Ros Eeles,Hans Ehrencrona,Ursula Eilber,Bent Ejlertsen,Arif B. Ekici,A. Heather Eliassen,A. Heather Eliassen,Christoph Engel,Mikael Eriksson,Laura Fachal,Laurence Faivre,Peter A. Fasching,Peter A. Fasching,Ulrike Faust,Jonine Figueroa,Dieter Flesch-Janys,Olivia Fletcher,Henrik Flyger,William D. Foulkes,Eitan Friedman,Eitan Friedman,Lin Fritschi,Debra Frost,Marike Gabrielson,Pragna Gaddam,Marilie D. Gammon,Patricia A. Ganz,Susan M. Gapstur,Judy Garber,Vanesa García-Barberán,José A. García-Sáenz,Mia M. Gaudet,Marion Gauthier-Villars,Andrea Gehrig,Vassilios Georgoulias,Anne-Marie Gerdes,Graham G. Giles,Graham G. Giles,Gord Glendon,Andrew K. Godwin,Mark S. Goldberg,David E. Goldgar,Anna González-Neira,Paul J. Goodfellow,Mark H. Greene,Grethe I. Grenaker Alnæs,Mervi Grip,Jacek Gronwald,Anne Grundy,Daphne Gschwantler-Kaulich,Pascal Guénel,Qi Guo,Lothar Haeberle,Eric Hahnen,Christopher A. Haiman,Niclas Håkansson,Emily Hallberg,Ute Hamann,N Hamel,Susan E. Hankinson,Thomas Hansen,Patricia Harrington,Steven N. Hart,Jaana M. Hartikainen,Catherine S. Healey,Alexander Hein,Sonja Helbig,Alex Henderson,Jane Heyworth,Belynda Hicks,Peter Hillemanns,Shirley Hodgson,Frans B. L. Hogervorst,Antoinette Hollestelle,Maartje J. Hooning,Bob Hoover,John L. Hopper,Chunling Hu,Guanmengqian Huang,Peter J. Hulick,Peter J. Hulick,Keith Humphreys,David J. Hunter,Evgeny N. Imyanitov,Claudine Isaacs,Motoki Iwasaki,Louise Izatt,Anna Jakubowska,Paul A. James,Paul A. James,Ramunas Janavicius,Wolfgang Janni,Uffe Birk Jensen,Esther M. John,Esther M. John,Nichola Johnson,Kristine Jones,Michael Jones,Arja Jukkola-Vuorinen,Rudolf Kaaks,Maria Kabisch,Katarzyna Kaczmarek,Daehee Kang,Daehee Kang,Karin Kast,Renske Keeman,Michael J. Kerin,Carolien M. Kets,Machteld Keupers,Sofia Khan,Elza Khusnutdinova,Elza Khusnutdinova,Johanna I. Kiiski,Sung Won Kim,Julia A. Knight,Julia A. Knight,Irene Konstantopoulou,Veli-Matti Kosma,Vessela N. Kristensen,Vessela N. Kristensen,Torben A Kruse,Ava Kwong,Anne-Vibeke Lænkholm,Yael Laitman,Fiona Lalloo,Diether Lambrechts,Keren Landsman,Christine Lasset,Conxi Lázaro,Loic Le Marchand,Julie Lecarpentier,Andy C. H. Lee,Eunjung Lee,Jong Won Lee,Min Hyuk Lee,Flavio Lejbkowicz,Fabienne Lesueur,Jingmei Li,Jenna Lilyquist,Anne Lincoln,Annika Lindblom,Jolanta Lissowska,Wing-Yee Lo,Wing-Yee Lo,Sibylle Loibl,Jirong Long,Jennifer T. Loud,Jan Lubinski,Craig Luccarini,Michael Lush,Robert J. MacInnis,Robert J. MacInnis,Tom Maishman,Enes Makalic,Ivana Maleva Kostovska,Kathleen E. Malone,Siranoush Manoukian,JoAnn E. Manson,Sara Margolin,John W.M. Martens,Maria Elena Martinez,Keitaro Matsuo,Dimitrios Mavroudis,Sylvie Mazoyer,Catriona McLean,Hanne Meijers-Heijboer,Primitiva Menéndez,J.-P. Meyer,Hui Miao,Austin Miller,Nicola Miller,Gillian Mitchell,Gillian Mitchell,Marco Montagna,Kenneth Muir,Kenneth Muir,Anna Marie Mulligan,Anna Marie Mulligan,Claire Mulot,Sue Nadesan,Katherine L. Nathanson,Susan L. Neuhausen,Heli Nevanlinna,Ines Nevelsteen,Dieter Niederacher,Sune F. Nielsen,Børge G. Nordestgaard,Børge G. Nordestgaard,Aaron D. Norman,Robert L. Nussbaum,Edith Olah,Olufunmilayo I. Olopade,Janet E. Olson,Curtis Olswold,Kai-ren Ong,Jan C. Oosterwijk,Nick Orr,Ana Osorio,V. Shane Pankratz,Laura Papi,Tjoung-Won Park-Simon,Ylva Paulsson-Karlsson,Rachel Lloyd,Inge Søkilde Pedersen,Bernard Peissel,Ana Peixoto,Jose Ignacio Arias Perez,Paolo Peterlongo,Julian Peto,Georg Pfeiler,Catherine M. Phelan,Mila Pinchev,Dijana Plaseska-Karanfilska,Bruce Poppe,Mary Porteous,Ross L. Prentice,Nadege Presneau,Darya Prokofieva,Elizabeth W. Pugh,Miquel Angel Pujana,Katri Pylkäs,Brigitte Rack,Brigitte Rack,Paolo Radice,Nazneen Rahman,Johanna Rantala,Christine Rappaport-Fuerhauser,Gad Rennert,Hedy S. Rennert,Valerie Rhenius,Kerstin Rhiem,Andrea L. Richardson,Gustavo C. Rodriguez,Atocha Romero,Jane Romm,Matti A. Rookus,Anja Rudolph,Thomas Ruediger,Emmanouil Saloustros,Joyce Sanders,Dale P. Sandler,Suleeporn Sangrajrang,Elinor J. Sawyer,Daniel F. Schmidt,Minouk J. Schoemaker,Fredrick R. Schumacher,Peter Schürmann,Lukas Schwentner,Christopher G. Scott,Rodney J. Scott,Rodney J. Scott,Sheila Seal,Leigha Senter,Caroline Seynaeve,Mitul Shah,Priyanka Sharma,Chen-Yang Shen,Chen-Yang Shen,Xin Sheng,Hermela Shimelis,Martha J. Shrubsole,Xiao-Ou Shu,Lucy Side,Christian F. Singer,Christof Sohn,Melissa C. Southey,John J. Spinelli,John J. Spinelli,Amanda B. Spurdle,Christa Stegmaier,Dominique Stoppa-Lyonnet,Grzegorz Sukiennicki,Harald Surowy,Harald Surowy,Christian Sutter,Anthony J. Swerdlow,Csilla Szabo,Rulla M. Tamimi,Rulla M. Tamimi,Yen Y. Tan,Jack A. Taylor,Maria-Isabel Tejada,Maria Tengström,Soo Hwang Teo,Mary Beth Terry,Daniel C. Tessier,Alex Teulé,Kathrin Thöne,Darcy L. Thull,Maria Grazia Tibiletti,Laima Tihomirova,Marc Tischkowitz,Amanda E. Toland,Rob A. E. M. Tollenaar,Ian Tomlinson,Ling Tong,Diana Torres,Diana Torres,Martine Tranchant,Thérèse Truong,Katherine L. Tucker,Nadine Tung,Jonathan Tyrer,Hans-Ulrich Ulmer,Celine M. Vachon,Christi J. van Asperen,David Van Den Berg,Ans M.W. van den Ouweland,Elizabeth J. van Rensburg,Liliana Varesco,Raymonda Varon-Mateeva,Ana Vega,Alessandra Viel,Joseph Vijai,Daniel Vincent,Jason Vollenweider,Lisa Walker,Zhaoming Wang,Shan Wang-Gohrke,Barbara Wappenschmidt,Clarice R. Weinberg,Jeffrey N. Weitzel,Camilla Wendt,Jelle Wesseling,Alice S. Whittemore,Juul T. Wijnen,Juul T. Wijnen,Walter C. Willett,Robert Winqvist,Alicja Wolk,Anna H. Wu,Lucy Xia,Xiaohong R. Yang,Drakoulis Yannoukakos,Daniela Zaffaroni,Wei Zheng,Bin Zhu,Argyrios Ziogas,Elad Ziv,Kristin K. Zorn,Manuela Gago-Dominguez,Arto Mannermaa,Håkan Olsson,Manuel R. Teixeira,Jennifer Stone,Jennifer Stone,Kenneth Offit,Laura Ottini,Sue K. Park,Sue K. Park,Mads Thomassen,Per Hall,Alfons Meindl,Rita K. Schmutzler,Arnaud Droit,Gary D. Bader,Paul D.P. Pharoah,Fergus J. Couch,Douglas F. Easton,Peter Kraft,Georgia Chenevix-Trench,Montserrat Garcia-Closas,Marjanka K. Schmidt,Antonis C. Antoniou,Jacques Simard +512 more
TL;DR: A genome-wide association study (GWAS) of predominantly estrogen receptor (ER)-positive disease and BRCA1 mutation carrier GWAS observed consistent associations with ER-negative disease for 105 susceptibility variants identified by other studies, which explain approximately 16% of the familial risk of this breast cancer subtype.