Author
Ellen Burgess
Other affiliations: Foothills Medical Centre, University of Alberta
Bio: Ellen Burgess is an academic researcher from University of Calgary. The author has contributed to research in topics: Blood pressure & Kidney disease. The author has an hindex of 39, co-authored 94 publications receiving 7154 citations. Previous affiliations of Ellen Burgess include Foothills Medical Centre & University of Alberta.
Papers published on a yearly basis
Papers
More filters
TL;DR: There remains a critical need to establish optimal therapeutic strategies and targets to improve clinical outcomes in patients with progressive renal disease, and the important modifiable risk factors are defined.
836 citations
McGill University Health Centre1, Foothills Medical Centre2, University of Calgary3, University of British Columbia4, McGill University5, University of Western Ontario6, Université du Québec à Trois-Rivières7, McMaster University8, Concordia University Wisconsin9, St. Michael's Hospital10, Ottawa Hospital Research Institute11, Memorial University of Newfoundland12, Montreal General Hospital13, Université de Montréal14, University of Saskatchewan15, Heart and Stroke Foundation of Canada16, Dalhousie University17, Hôpital Maisonneuve-Rosemont18, University of Toronto19, Laval University20, University of Alberta21, Université de Sherbrooke22, University Health Network23, University of Manitoba24, University of Ottawa25, Université du Québec à Montréal26, Centre for Addiction and Mental Health27, Canadian Stroke Network28, Department of National Defence29, Northern Ontario School of Medicine30
TL;DR: The Canadian Hypertension Education Program reviews the hypertension literature annually and provides detailed recommendations regarding hypertension diagnosis, assessment, prevention, and treatment, and 4 new recommendations were added and 2 existing recommendations were modified this year.
683 citations
University of Calgary1, McGill University Health Centre2, Cardiovascular Institute of the South3, University of British Columbia4, Université du Québec à Trois-Rivières5, Université de Montréal6, Laval University7, McMaster University8, Alberta Health Services9, University of Alberta10, McGill University11, University of Toronto12, Heart and Stroke Foundation of Canada13, Population Health Research Institute14, Montreal General Hospital15, University of Western Ontario16, Montreal Heart Institute17, Winnipeg Regional Health Authority18, Université du Québec à Montréal19, Northern Ontario School of Medicine20, St. Michael's Hospital21, University of Manitoba22, Centre for Addiction and Mental Health23, University of Ottawa24, University Health Network25, Concordia University Wisconsin26, Ottawa Hospital Research Institute27, University of Ontario Institute of Technology28, Hôpital Maisonneuve-Rosemont29, University of Saskatchewan30, Centre Hospitalier Universitaire Sainte-Justine31, Children's Hospital of Eastern Ontario32, St Thomas' Hospital33, Mount Sinai Hospital, Toronto34, Université de Sherbrooke35, Brown University36, Concordia Hospital37, University of Pennsylvania38
TL;DR: All individuals with hypertension should have an assessment of global cardiovascular risk to promote health behaviours that lower blood pressure, and an angiotensin receptor-neprilysin inhibitor combination should be used in place of either an ang Elliotensin-converting enzyme inhibitor or angiotENSin receptor blocker in individuals with heart failure.
465 citations
University of Calgary1, McGill University Health Centre2, Université du Québec à Trois-Rivières3, University of British Columbia4, Université de Montréal5, Laval University6, University of Alberta7, University of Toronto8, Ottawa Hospital Research Institute9, Hôpital Maisonneuve-Rosemont10, Memorial University of Newfoundland11, Centre for Addiction and Mental Health12, University of Ottawa13, McGill University14, University Health Network15, University of Western Ontario16, University of Saskatchewan17, University of Manitoba18, Concordia University Wisconsin19, Montreal General Hospital20, Heart and Stroke Foundation of Canada21, Dalhousie University22, Libin Cardiovascular Institute of Alberta23, Université de Sherbrooke24, McMaster University25, Université du Québec à Montréal26, Montreal Heart Institute27, Canadian Stroke Network28, Department of National Defence29, Simon Fraser University30, St George's, University of London31, Centre Hospitalier Universitaire Sainte-Justine32, Children's Hospital of Eastern Ontario33
TL;DR: In the diagnosis and assessment of hypertension, automated office blood pressure, taken without patient-health provider interaction, is now recommended as the preferred method of measuring in-office blood pressure as mentioned in this paper.
413 citations
University of Western Ontario1, University of British Columbia2, University of Calgary3, Ottawa Hospital Research Institute4, University of Alberta5, Canadian Stroke Network6, Jewish General Hospital7, University of Ottawa8, Université de Montréal9, Laval University10, University Health Network11, Queen Elizabeth II Health Sciences Centre12, McGill University13, Concordia University14, Lawson Health Research Institute15, Université de Sherbrooke16, University of Saskatchewan17, Hôpital Maisonneuve-Rosemont18, University of Toronto19, St. Michael's Hospital20, Toronto Western Hospital21, University of Manitoba22, Sunnybrook Health Sciences Centre23
TL;DR: The evidence-based recommendations for the prevention and treatment of hypertension in adults for 2010 are updated and treatment thresholds and targets should be predicated on the patient's global atherosclerotic risk, target organ damage and comorbid conditions.
395 citations
Cited by
More filters
TL;DR: It was agreed that there should not be an obligatory component, but that waist measurement would continue to be a useful preliminary screening tool, and a single set of cut points would be used for all components except waist circumference, for which further work is required.
Abstract: A cluster of risk factors for cardiovascular disease and type 2 diabetes mellitus, which occur together more often than by chance alone, have become known as the metabolic syndrome. The risk factors include raised blood pressure, dyslipidemia (raised triglycerides and lowered high-density lipoprotein cholesterol), raised fasting glucose, and central obesity. Various diagnostic criteria have been proposed by different organizations over the past decade. Most recently, these have come from the International Diabetes Federation and the American Heart Association/National Heart, Lung, and Blood Institute. The main difference concerns the measure for central obesity, with this being an obligatory component in the International Diabetes Federation definition, lower than in the American Heart Association/National Heart, Lung, and Blood Institute criteria, and ethnic specific. The present article represents the outcome of a meeting between several major organizations in an attempt to unify criteria. It was agreed that there should not be an obligatory component, but that waist measurement would continue to be a useful preliminary screening tool. Three abnormal findings out of 5 would qualify a person for the metabolic syndrome. A single set of cut points would be used for all components except waist circumference, for which further work is required. In the interim, national or regional cut points for waist circumference can be used.
11,737 citations
TL;DR: The longitudinal glomerular filtration rate was estimated among 1,120,295 adults within a large, integrated system of health care delivery in whom serum creatinine had been measured between 1996 and 2000 and who had not undergone dialysis or kidney transplantation.
Abstract: Background End-stage renal disease substantially increases the risks of death, cardiovascular disease, and use of specialized health care, but the effects of less severe kidney dysfunction on these outcomes are less well defined. Methods We estimated the longitudinal glomerular filtration rate (GFR) among 1,120,295 adults within a large, integrated system of health care delivery in whom serum creatinine had been measured between 1996 and 2000 and who had not undergone dialysis or kidney transplantation. We examined the multivariable association between the estimated GFR and the risks of death, cardiovascular events, and hospitalization. Results The median follow-up was 2.84 years, the mean age was 52 years, and 55 percent of the group were women. After adjustment, the risk of death increased as the GFR decreased below 60 ml per minute per 1.73 m2 of body-surface area: the adjusted hazard ratio for death was 1.2 with an estimated GFR of 45 to 59 ml per minute per 1.73 m2 (95 percent confidence interval, 1....
9,642 citations
TL;DR: The results reveal that happiness is associated with and precedes numerous successful outcomes, as well as behaviors paralleling success, and the evidence suggests that positive affect may be the cause of many of the desirable characteristics, resources, and successes correlated with happiness.
Abstract: Numerous studies show that happy individuals are successful across multiple life domains, including marriage, friendship, income, work performance, and health. The authors suggest a conceptual model to account for these findings, arguing that the happiness-success link exists not only because success makes people happy, but also because positive affect engenders success. Three classes of evidence--crosssectional, longitudinal, and experimental--are documented to test their model. Relevant studies are described and their effect sizes combined meta-analytically. The results reveal that happiness is associated with and precedes numerous successful outcomes, as well as behaviors paralleling success. Furthermore, the evidence suggests that positive affect--the hallmark of well-being--may be the cause of many of the desirable characteristics, resources, and successes correlated with happiness. Limitations, empirical issues, and important future research questions are discussed.
5,713 citations
TL;DR: In a meta-analysis, Julianne Holt-Lunstad and colleagues find that individuals' social relationships have as much influence on mortality risk as other well-established risk factors for mortality, such as smoking.
Abstract: Background
The quality and quantity of individuals' social relationships has been linked not only to mental health but also to both morbidity and mortality.
Objectives
This meta-analytic review was conducted to determine the extent to which social relationships influence risk for mortality, which aspects of social relationships are most highly predictive, and which factors may moderate the risk.
Data Extraction
Data were extracted on several participant characteristics, including cause of mortality, initial health status, and pre-existing health conditions, as well as on study characteristics, including length of follow-up and type of assessment of social relationships.
Results
Across 148 studies (308,849 participants), the random effects weighted average effect size was OR = 1.50 (95% CI 1.42 to 1.59), indicating a 50% increased likelihood of survival for participants with stronger social relationships. This finding remained consistent across age, sex, initial health status, cause of death, and follow-up period. Significant differences were found across the type of social measurement evaluated (p<0.001); the association was strongest for complex measures of social integration (OR = 1.91; 95% CI 1.63 to 2.23) and lowest for binary indicators of residential status (living alone versus with others) (OR = 1.19; 95% CI 0.99 to 1.44).
Conclusions
The influence of social relationships on risk for mortality is comparable with well-established risk factors for mortality.
Please see later in the article for the Editors' Summary
5,070 citations
TL;DR: Since 1980, the American College of Cardiology and American Heart Association have translated scientific evidence into clinical practice guidelines (guidelines) with recommendations to improve cardiovascular health.
Abstract: Since 1980, the American College of Cardiology (ACC) and American Heart Association (AHA) have translated scientific evidence into clinical practice guidelines (guidelines) with recommendations to improve cardiovascular health. In 2013, the National Heart, Lung, and Blood Institute (NHLBI) Advisory
4,604 citations