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Emanuel Goldman

Bio: Emanuel Goldman is an academic researcher from Rutgers University. The author has contributed to research in topics: Transfer RNA & Messenger RNA. The author has an hindex of 24, co-authored 79 publications receiving 2581 citations. Previous affiliations of Emanuel Goldman include University of Medicine and Dentistry of New Jersey & Massachusetts Institute of Technology.


Papers
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Journal ArticleDOI
TL;DR: The availability of X-ray crystallographic structures of some synthetases, combined with site-directed mutagenesis, allows insights into molecular details of the extraordinary selectivity of synthetase, including the editing function.

281 citations

Book
30 Jun 1989
TL;DR: PRACTICAL INFORMATION and PROCEDURES for MICROBIOLOGY Sterilization, Disinfection, and Antisepsis Michael G. Schmidt Quantitation of Microorganisms Peter S. Lee Culturing and Preserving Microorganisms Lorrence H. Green Epidemiological Methods in Microbiology Ashley Robinson Business of Microbiology Michael C. Nugent and LorrenceH.
Abstract: PRACTICAL INFORMATION AND PROCEDURES FOR MICROBIOLOGY Sterilization, Disinfection, and Antisepsis Michael G. Schmidt Quantitation of Microorganisms Peter S. Lee Culturing and Preserving Microorganisms Lorrence H. Green Stains for Light Microscopy Stuart Chaskes and Rita Austin Identification of Gram-Positive Organisms Peter M. Colaninno Identification of Aerobic Gram-Negative Bacteria Donna J. Kohlerschmidt, Lisa A. Mingle, and Nellie B. Dumas Plaque Assay for Bacteriophage Emanuel Goldman Phage Identification of Bacteria Catherine E.D. Rees, Lorrence H. Green, Emanuel Goldman, and Martin J. Loessner Phage Display and Selection of Protein Ligands Wlodek Mandecki, Emanuel Goldman, Inger Sandlie, and Geir Age Loset Diagnostic Medical Microbiology Lorrence H. Green Mechanisms of Action of Antibacterial Agents Joseph Adrian L. Buensalido, Carmen E. DeMarco, and Stephen A. Lerner Mechanisms of Action of Antifungal Agents Stephanie A. Flowers and P. David Rogers Mechanisms of Action of Antiviral Agents Guido Antonelli and Ombretta Turriziani Antibiotic Susceptibility Testing Audrey Wanger Bacterial Cell Wall: Morphology and Biochemistry Jed F. Fisher and Shahriar Mobashery Bacterial Cell Breakage or Lysis Matthew E. Bahamonde Major Culture Collections and Sources Lorrence H. Green Epidemiological Methods in Microbiology Ashley Robinson Business of Microbiology Michael C. Nugent and Lorrence H. Green INFORMATION ON INDIVIDUAL GENUS AND SPECIES, AND OTHER TOPICS The Family Enterobacteriaceae J. Michael Janda and Sharon L. Abbott The Genus Pseudomonas Shubham Chakravarty and Gregory G. Anderson The Family Neisseriaceae Yvonne A. Lue Microbiological and Clinical Aspects of the Pathogenic Spirochetes Charles Pavia The Genus Vibrio and Related Genera Seon Young Choi, Jongsik Chun, and Rita R. Colwell Staphylococcus aureus and Related Staphylococci Dominique Missiakas and Olaf Schneewind Streptococcus Vincent A. Fischetti and Patricia Ryan The Genus Bacillus Daniel R. Zeigler and John B. Perkins Clostridium Peter Durre The Genus Corynebacterium Lothar Eggeling and Michael Bott The Actinobacteria Alan C. Ward and Nagamani Bora The Family Rickettsiaceae Magda Beier-Sexton, Timothy P. Driscoll, Abdu F. Azad, and Joseph J. Gillespie Chlamydia Lourdes G. Bahamonde Mycoplasma and Related Organisms Meghan May and Daniel R. Brown The Genus Mycobacteria Salman H. Siddiqi The Genus Legionella Alexander W. Ensminger, Eva M. Campodonico, and Craig R. Roy Haemophilus species Elisabeth Adderson Listeria Sukhadeo Barbuddhe, Torsten Hain, and Trinad Chakraborty The Genus Campylobacter Collette Fitzgerald, Janet Pruckler, Maria Karlsson, and Patrick Kwan The Genus Helicobacter Ernestine M. Vellozzi and Edmund R. Giugliano The Genus Yersinia Susan E. Sharp The Genus Bordetella Rita Austin and Tonya Shearin-Patterson Other Gram-Negative Bacteria: Acinetobacter, Burkholderia, and Moraxella Rebecca E. Colman and Jason W. Sahl Selected Zoonotic Pathogens Sanjay K. Shukla and Steven Foley Other Anaerobic Bacteria: Bacteroides, Porphyromonas, Prevotella, Tannerella, Fusobacterium, and Gram-Positive Anaerobic Cocci Joseph J. Zambon and Violet I. Haraszthy Archaea Sarah T. Gross Overview of Biofilms and Some Key Methods for Their Study Paramita Basu, Irvin N. Hirshfield, and Subit Barua Introduction to Bacteriophages Elizabeth Kutter and Emanuel Goldman Phage Therapy: Bacteriophages as Natural, Self-Replicating Antimicrobials Elizabeth Kutter Introduction to Parasites Purnima Bhanot and Fred Schuster Fungi Michael Dalto and Jeffrey Daniels Introduction to Virology Ken S. Rosenthal Survey of Selected Clinical, Commercial, and Research-Model Eubacterial Species Emanuel Goldman

222 citations

Journal ArticleDOI
30 Aug 1991-Gene
TL;DR: Low-usage codons are clearly avoided in genes encoding abundant proteins for ECO, YSC DRO, and several species of primates, with an emphasis on characterization of low- usage codons.

196 citations


Cited by
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28 Jul 2005
TL;DR: PfPMP1)与感染红细胞、树突状组胞以及胎盘的单个或多个受体作用,在黏附及免疫逃避中起关键的作�ly.
Abstract: 抗原变异可使得多种致病微生物易于逃避宿主免疫应答。表达在感染红细胞表面的恶性疟原虫红细胞表面蛋白1(PfPMP1)与感染红细胞、内皮细胞、树突状细胞以及胎盘的单个或多个受体作用,在黏附及免疫逃避中起关键的作用。每个单倍体基因组var基因家族编码约60种成员,通过启动转录不同的var基因变异体为抗原变异提供了分子基础。

18,940 citations

Journal ArticleDOI
01 Jan 1981-Cell
TL;DR: Three transformed lines of simian cells were established and found to contain T antigen; retain complete permissiveness for lytic growth of SV40; support the replication of tsA209 virus at 40 degrees C; and support the replicate of pure populations of SV 40 mutants with deletions in the early region.

2,445 citations

Journal ArticleDOI
20 Apr 2001-Science
TL;DR: A unique transfer RNA/aminoacyl-tRNA synthetase pair has been generated that expands the number of genetically encoded amino acids in Escherichia coli and should provide a general method for increasing the genetic repertoire of living cells to include a variety of amino acids with novel structural, chemical, and physical properties not found in the common 20 amino acids.
Abstract: A unique transfer RNA (tRNA)/aminoacyl-tRNA synthetase pair has been generated that expands the number of genetically encoded amino acids in Escherichia coli. When introduced into E. coli, this pair leads to the in vivo incorporation of the synthetic amino acid O-methyl-l-tyrosine into protein in response to an amber nonsense codon. The fidelity of translation is greater than 99%, as determined by analysis of dihydrofolate reductase containing the unnatural amino acid. This approach should provide a general method for increasing the genetic repertoire of living cells to include a variety of amino acids with novel structural, chemical, and physical properties not found in the common 20 amino acids.

1,495 citations

Journal ArticleDOI
TL;DR: The finding that the frequency of usage of optimal codons is closely correlated with the production levels of individual genes was discussed from an evolutionary viewpoint.

1,357 citations

Journal ArticleDOI
TL;DR: Ongoing work to quantify the dynamics of initiation and elongation is as important for understanding natural synonymous variation as it is for designing transgenes in applied contexts.
Abstract: Despite their name, synonymous mutations have significant consequences for cellular processes in all taxa. As a result, an understanding of codon bias is central to fields as diverse as molecular evolution and biotechnology. Although recent advances in sequencing and synthetic biology have helped to resolve longstanding questions about codon bias, they have also uncovered striking patterns that suggest new hypotheses about protein synthesis. Ongoing work to quantify the dynamics of initiation and elongation is as important for understanding natural synonymous variation as it is for designing transgenes in applied contexts.

1,318 citations