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Emanuele Sinagra
Researcher at University of Palermo
Publications - 127
Citations - 1466
Emanuele Sinagra is an academic researcher from University of Palermo. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 16, co-authored 102 publications receiving 1024 citations.
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Nutrition, oxidative stress and intestinal dysbiosis: Influence of diet on gut microbiota in inflammatory bowel diseases.
Giovanni Tomasello,Margherita Mazzola,Angelo Leone,Emanuele Sinagra,Giovanni Zummo,Felicia Farina,Provvidenza Damiani,Francesco Cappello,Alice Gerges Geagea,Alice Gerges Geagea,Abdo Jurjus,Tarek Bou Assi,M. Messina,Francesco Carini +13 more
TL;DR: The "Western diet", in particular a low - fiber high fat/high carbohydrate diet is one factor that can lead to severe dysbiosis, in contrast, "mediterranean" and vegetarian diets that includes abundant fruits, vegetables, olive oil and oily fish are known for their anti-inflammatory effects and could prevent Dysbiosis and subsequent inflammatory bowel disease.
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Systematic review with meta-analysis: the haemodynamic effects of carvedilol compared with propranolol for portal hypertension in cirrhosis
TL;DR: Carvedilol is a nonselective beta‐blocker with a mild anti‐alfa‐1‐adrenergic activity that is recommended for prophylaxis of variceal bleeding in cirrhosis and several studies have compared carvedilol and propranolol, yielding inconsistent results.
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Screening of colorectal cancer: present and future
Marcello Maida,Fabio Salvatore Macaluso,Gianluca Ianiro,Francesca Mangiola,Emanuele Sinagra,Georgina L. Hold,Carlo Maida,Giovanni Cammarota,Antonio Gasbarrini,G. Scarpulla +9 more
TL;DR: The aim of this paper is to review the current published evidence from literature which assesses the performance and effectiveness of different screening tests for the early detection of CRC.
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Dismicrobism in inflammatory bowel disease and colorectal cancer: Changes in response of colocytes
Giovanni Tomasello,Tralongo P,Provvidenza Damiani,Emanuele Sinagra,Benedetto Di Trapani,Marie Noelle Zeenny,Inaya Hajj Hussein,Abdo Jurjus,Angelo Leone +8 more
TL;DR: Increasing evidence indicates that dysbiosis favors the production of genotoxins and metabolites associated with carcinogenesis and induces dysregulation of the immune response which promotes and sustains inflammation in IBD leading to carcinogenesis.
Journal ArticleDOI
Inflammation in irritable bowel syndrome: Myth or new treatment target?
Emanuele Sinagra,Giancarlo Pompei,Giovanni Tomasello,Francesco Cappello,Gaetano Cristian Morreale,Georgios Amvrosiadis,Francesca Rossi,Attilio Ignazio Lo Monte,Aroldo Rizzo,Dario Raimondo +9 more
TL;DR: The aim of this review was to summarize the evidence on the spectrum of mucosal inflammation in IBS, highlighting the relationship of this inflammation to the pathophysiology of IBS and its connection to clinical practice.