E
Emiliano Panieri
Researcher at University of Turin
Publications - 25
Citations - 1888
Emiliano Panieri is an academic researcher from University of Turin. The author has contributed to research in topics: Medicine & Oxidative stress. The author has an hindex of 12, co-authored 19 publications receiving 1354 citations. Previous affiliations of Emiliano Panieri include Catholic University of the Sacred Heart & Karolinska Institutet.
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ROS homeostasis and metabolism: a dangerous liason in cancer cells.
TL;DR: How the mitochondria has a key role in regulating the interplay between redox homeostasis and metabolism within tumor cells is described, and the potential therapeutic use of agents that directly or indirectly block metabolism is discussed.
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Pro-metastatic signaling by c-Met through RAC-1 and reactive oxygen species (ROS).
Daniela A. Ferraro,Simona Corso,Elena Fasano,Emiliano Panieri,Rosaria Santangelo,Silvia Borrello,Silvia Giordano,Giovambattista Pani,Tommaso Galeotti +8 more
TL;DR: A novel cascade triggered by c-Met and mediated by ROS, linked to metastasis and potentially targetable by new antimetastatic, redox-based therapies is outlined.
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Potential Applications of NRF2 Inhibitors in Cancer Therapy.
Emiliano Panieri,Luciano Saso +1 more
TL;DR: Some of the most promising therapeutic approaches that have been successfully employed to counteract NRF2 activity in tumors are described, with a particular emphasis on the development of natural compounds and the adoption of drug repurposing strategies.
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Reactive oxygen species generated in different compartments induce cell death, survival, or senescence.
Emiliano Panieri,Vladimir Gogvadze,Erik Norberg,Rithika Venkatesh,Sten Orrenius,Boris Zhivotovsky +5 more
TL;DR: It is demonstrated that high levels of exogenously generated H2O2 induce extensive DNA damage, ATP depletion, and severe cytotoxicity, and could-at least in part-be prevented by RIP1 kinase inhibition.
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ROS signaling and redox biology in endothelial cells
Emiliano Panieri,Massimo Santoro +1 more
TL;DR: Which molecules are involved in redox signaling and how they influence the relationship between ECs and other vascular component with regard to angiogenesis are described.