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Emilio Russo

Researcher at Magna Græcia University

Publications -  301
Citations -  7702

Emilio Russo is an academic researcher from Magna Græcia University. The author has contributed to research in topics: Epilepsy & Medicine. The author has an hindex of 43, co-authored 270 publications receiving 5989 citations. Previous affiliations of Emilio Russo include University of Calabria & University of Messina.

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Nonpsychotropic plant cannabinoids, cannabidivarin (CBDV) and cannabidiol (CBD), activate and desensitize transient receptor potential vanilloid 1 (TRPV1) channels in vitro: potential for the treatment of neuronal hyperexcitability.

TL;DR: The data suggest that CBDV antiepileptiform effects in the Mg(2+)-free model are not uniquely mediated via activation of TRPV1, and it is proposed that CBDv effects on TRP channels should be studied further in different in vitro and in vivo models of epilepsy.
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Phthalates: European regulation, chemistry, pharmacokinetic and related toxicity

TL;DR: The molecular and cellular mechanisms involved in organ toxicity of phthalates are discussed; furthermore, pharmacokinetic, chemistry and the European regulation are summarized.
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Corticosteroid-related central nervous system side effects

TL;DR: The correlation between the administration of corticosteroids and CNS adverse effects is highlighted, giving a useful guide for prescribers including a more careful assessment of risk factors and encourage the use of safer doses of this class of drugs.
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Hypericum perforatum: pharmacokinetic, mechanism of action, tolerability, and clinical drug-drug interactions.

TL;DR: The existing evidence describing the clinical consequence of HP–drug interactions is analysed and case reports where causality can be determined to reveal clinically significant interactions that suggest caution, consideration, and disclosure of potential interactions prior to informed use of HP are analyzed.
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mTOR pathway inhibition as a new therapeutic strategy in epilepsy and epileptogenesis

TL;DR: MTOR is currently a very good candidate as a target for epilepsy and epileptogenesis and its potential as a therapeutic target in epilepsy treatment is described by presenting the most recent findings on mTOR inhibitors.