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Eng-King Tan

Researcher at National University of Singapore

Publications -  575
Citations -  21580

Eng-King Tan is an academic researcher from National University of Singapore. The author has contributed to research in topics: Parkinson's disease & Medicine. The author has an hindex of 67, co-authored 513 publications receiving 16807 citations. Previous affiliations of Eng-King Tan include Taipei Medical University & Singapore General Hospital.

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Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease

Ellen Sidransky, +75 more
- 22 Oct 2009 - 
TL;DR: Data collected demonstrate that there is a strong association between GBA mutations and Parkinson's disease, and those with a GBA mutation presented earlier with the disease, were more likely to have affected relatives, and were morelikely to have atypical clinical manifestations.
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Midbrain-like Organoids from Human Pluripotent Stem Cells Contain Functional Dopaminergic and Neuromelanin-Producing Neurons

Junghyun Jo, +25 more
- 04 Aug 2016 - 
TL;DR: A method to differentiate human pluripotent stem cells into a large multicellular organoid-like structure that contains distinct layers of neuronal cells expressing characteristic markers of human midbrain is developed.
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Collaborative analysis of alpha-synuclein gene promoter variability and Parkinson disease.

Demetrius M. Maraganore, +27 more
- 09 Aug 2006 - 
TL;DR: This large-scale collaborative analysis demonstrates that SNCA REP1 allele-length variability is associated with an increased risk of Parkinson disease.
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Parkinson's disease: etiopathogenesis and treatment.

Joseph Jankovic, +1 more
- 23 Jun 2020 - 
TL;DR: The involvement of dopaminergic as well as noradrenergic, glutamatergic, serotonergic and adenosine pathways provide insights into the rich and variable clinical phenomenology associated with PD and the possibility of alternative therapeutic approaches beyond traditional dopamine replacement therapies.