E
Eric J. Topol
Researcher at Scripps Health
Publications - 1406
Citations - 162373
Eric J. Topol is an academic researcher from Scripps Health. The author has contributed to research in topics: Myocardial infarction & Angioplasty. The author has an hindex of 193, co-authored 1373 publications receiving 151025 citations. Previous affiliations of Eric J. Topol include Loyola University Chicago & Cleveland Clinic.
Papers
More filters
Journal ArticleDOI
Relation of temporal creatine kinase-MB release and outcome after thrombolytic therapy for acute myocardial infarction
Robert H. Christenson,Robin T. Vollmer,E. Magnus Ohman,Stephen Peck,Trevor D. Thompson,Show-Hong Duh,Stephen G. Ellis,L. Kristin Newby,Eric J. Topol,Robert M. Califf +9 more
TL;DR: It is concluded that CK-MB maximums relate to infarct zone function, left ventricular function, and in-hospital outcomes after thrombolysis for acute myocardial infarction.
Journal ArticleDOI
Survival outcomes 1 year after reperfusion therapy with either alteplase or reteplase for acute myocardial infarction: results from the Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries (GUSTO) III Trial.
Eric J. Topol,E. Magnus Ohman,Paul W. Armstrong,Robert G. Wilcox,Alan M. Skene,Philip E. Aylward,John Simes,Anthony J. Dalby,Amadeo Betriu,Christoph Bode,Harvey D. White,Judith S. Hochman,Hakan Emanuelson,Alec Vahanian,Shelly Sapp,Amanda Stebbins,David J. Moliterno,Robert M. Califf +17 more
TL;DR: The r-PA and t-PA strategies yielded similar survival outcomes after 30 days in this trial, and the increase in mortality rate during extended follow-up compared with previous trials may reflect higher-risk patients and highlights the need for improved secondary prevention strategies.
Journal ArticleDOI
Selective inhibition of factor Xa during thrombolytic therapy markedly improves coronary artery patency in a canine model of coronary thrombosis
Francesca A. Nicolini,Pauline Lee,Janis L. Malycky,Jeffrey Lefkovits,Kandice Kottke-Marchant,Edward F. Plow,Eric J. Topol +6 more
TL;DR: It is suggested that adjunctive treatment with a higher tier blockade of the coagulation cascade is superior to direct thrombin inhibition in maintaining coronary artery patency following thrombolysis in the experimental canine electrolytic model.
Journal ArticleDOI
Striking Prognostic Significance of elevated CRP in Renal Impairment patients undergoing PCI
Mark Robbins,Derek P. Chew,Deepak L. Bhatt,Abdulhay Albirini,Leslie Cho,Jakob P. Schneider,Stephen G. Ellis,Eric J. Topol +7 more
Journal ArticleDOI
Thrombospondins, Their Polymorphisms, and Cardiovascular Disease
TL;DR: This review seeks to summarize current information that has emerged on how the thrombospondins influence cardiovascular pathology, to dissect how the individual polymorphisms alter the structure and function of the parent throm bospondin molecules, and to replicate the genetic data in different patient populations.