E
Eric J. Topol
Researcher at Scripps Health
Publications - 1406
Citations - 162373
Eric J. Topol is an academic researcher from Scripps Health. The author has contributed to research in topics: Myocardial infarction & Angioplasty. The author has an hindex of 193, co-authored 1373 publications receiving 151025 citations. Previous affiliations of Eric J. Topol include Loyola University Chicago & Cleveland Clinic.
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Journal ArticleDOI
Inducible Carboxypeptidase Activity: A Role in Clot Lysis In Vivo
TL;DR: Data indicate that carboxypeptidase activity is induced in vivo and may influence thrombolysis in dogs with electrically induced thrombosis of the circumflex coronary artery treated with TPA.
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Eptifibatide and low-dose tissue plasminogen activator in acute myocardial infarction: The integrilin and low-dose thrombolysis in acute myocardial infarction (INTRO AMI) trial
Sorin J. Brener,Nadine Juran,Stephen G. Ellis,Thomas B. Ivanc,Eric J. Topol,Uwe Zeymer,A. A. Jennifer Adgey,Thomas R. Vrobel,Karl-Ludwig Neuhaus,E. Magnus Ohman,John Strony,Michael M. Kitt +11 more
TL;DR: Testing the hypothesis that eptifibatide and reduced-dose tissue plasminogen activator (t-PA) will enhance infarct artery patency at 60 min in patients with acute myocardial infarction found this therapy is associated with improved quality and speed of reperfusion.
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Defining the appropriate threshold of creatine kinase elevation after percutaneous coronary interventions
TL;DR: This study shows that CK elevations between 2 and 5 times control values after successful coronary interventions are associated with an adverse long-term outcome, and suggests that an appropriate CK threshold that has prognostic implications would be twice the upper limit of normal.
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Effect of clopidogrel pretreatment on periprocedural rise in C-reactive protein after percutaneous coronary intervention.
Deepak P. Vivekananthan,Deepak L. Bhatt,Derek P. Chew,Frank J. Zidar,Albert W. Chan,David J. Moliterno,Stephen G. Ellis,Eric J. Topol +7 more
TL;DR: Clopidogrel pretreatment attenuated the periprocedural increase in CRP by 65% and was independently associated with an attenuation in the CRP increase in a multivariate model.
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Relation between lesion characteristics and risk with percutaneous intervention in the stent and glycoprotein IIb/IIIa era: An analysis of results from 10,907 lesions and proposal for new classification scheme.
TL;DR: Appreciation of contemporary risk factors for complications of coronary intervention may assist in patient selection and in risk adjustment for comparison of outcomes between providers.