Eric J. Topol

TL;DR: Although the findings regarding the influence of glycemic-control strategies should be interpreted with caution because of the exploratory nature of the analyses and the relatively small sample size of the insulin-sensitizing group, the improved risk-adjusted outcomes associated with insulin-aided therapy underscore the need to further evaluate treatment strategies for patients with diabetes and CAD.

TL;DR: Sib‐TDT analysis showed that three of the four SNPs could confer significant susceptibility to premature CAD and MI, indicating that the fourSNPs on chromosome 9p21 are also associated with premature, familial CAD.

TL;DR: These data show that inhibition of specific pathways of platelet and thrombin activity improves the extent and duration of rTPA-induced thrombolysis in the electrolytic canine model and suggest that low doses of platelets IIb/IIIa and direct throm bin antagonists in combination may be used successfully during thrombosis.

TL;DR: It is suggested that QRS complex and ST segment monitoring with continuous on-line vectorcardiography has substantial potential for monitoring patients with acute myocardial infarction treated with reperfusion therapy.

TL;DR: It is concluded that diabetic retinopathy should not be considered a contraindication to thrombolysis in patients with an acute myocardial infarction.