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Eric Riedel
Researcher at Children's Hospital of Philadelphia
Publications - 8
Citations - 478
Eric Riedel is an academic researcher from Children's Hospital of Philadelphia. The author has contributed to research in topics: Peripheral blood mononuclear cell & Immune system. The author has an hindex of 7, co-authored 8 publications receiving 453 citations. Previous affiliations of Eric Riedel include University of Pennsylvania.
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Journal ArticleDOI
Optimization and Limitations of Use of Cryopreserved Peripheral Blood Mononuclear Cells for Functional and Phenotypic T-Cell Characterization
Adriana Weinberg,Lin-Ye Song,Cynthia L. Wilkening,Anne Sevin,Bruce Blais,Raul Louzao,Dana Stein,Patricia Defechereux,Deborah Durand,Eric Riedel,Nancy Raftery,Renee Jesser,Betty S. Brown,M. Fran Keller,Ruth Dickover,Elizabeth J. McFarland,Terence Fenton +16 more
TL;DR: It was determined that slowly diluting the thawed PBMC significantly improved viable cell recovery, whereas the use of benzonase improved cell recovery only sometimes, and LPA and flow cytometry assay results for cryopreserved and fresh PBMC were highly correlated.
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Lambda Interferon Inhibits Human Immunodeficiency Virus Type 1 Infection of Macrophages
TL;DR: In this paper, the newly identified type III interferon (IFN-λ) has antiviral activity against a broad spectrum of viruses, including HIV-1 infection and replication.
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Interleukin-1β Upregulates Functional Expression of Neurokinin-1 Receptor (NK-1R) via NF-κB in Astrocytes
Chang-Jiang Guo,Steven D. Douglas,Zhiyong Gao,Bryan A. Wolf,Judith B. Grinspan,Jian-Ping Lai,Eric Riedel,Wen-Zhe Ho +7 more
TL;DR: Findings provide additional evidence that there is a biological interaction between IL‐1β and the neuropeptide SP in the central nervous system, which may have important implications in the inflammatory diseases in the CNS.
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Cryopreservation decreases receptor PD-1 and ligand PD-L1 coinhibitory expression on peripheral blood mononuclear cell-derived T cells and monocytes.
Donald E. Campbell,Nancy B. Tustin,Eric Riedel,Richard Tustin,J. Taylor,Jennifer B. Murray,Steven D. Douglas +6 more
TL;DR: Cryopreservation significantly reduced the expression of both PD-1 and PD-L1 on PBMC-derived CD3+/ CD8+ T cells and CD45+/CD14+ monocytes obtained from adult control subjects, and coinhibitory signaling blockade of freshly isolated, PHA-stimulated PBMC from normal adult controls and human immunodeficiency virus (HIV)-infected subjects led to increased production of IL-4 and IL-5.
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Quantification of CCR5 mRNA in human lymphocytes and macrophages by real-time reverse transcriptase PCR assay.
TL;DR: A newly developed real-time reverse transcriptase PCR (RT-PCR) assay for the quantification of CCR5 mRNA in human blood immune cells has the potential and a wide application for the investigation of the role of C CR5 in inflammatory diseases and viral infections, including HIV disease.