E
Erik Holtzapple
Researcher at J. Craig Venter Institute
Publications - 17
Citations - 4442
Erik Holtzapple is an academic researcher from J. Craig Venter Institute. The author has contributed to research in topics: Genome & Wax ester. The author has an hindex of 10, co-authored 17 publications receiving 4278 citations. Previous affiliations of Erik Holtzapple include ExxonMobil & University of Minnesota.
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Journal ArticleDOI
Complete Genome Sequence of a Virulent Isolate of Streptococcus pneumoniae
Hervé Tettelin,Karen E. Nelson,Ian T. Paulsen,Jonathan A. Eisen,Timothy D. Read,Scott N. Peterson,John F. Heidelberg,Robert T. DeBoy,Daniel H. Haft,Robert J. Dodson,Anthony S. Durkin,Michelle L. Gwinn,James F. Kolonay,William C. Nelson,Jeremy Peterson,Lowell Umayam,Owen White,Steven L. Salzberg,Matthew R. Lewis,Diana Radune,Erik Holtzapple,Hoda Khouri,Alex M. Wolf,T. Utterback,Cheryl L. Hansen,Lisa McDonald,Tamara Feldblyum,Samuel V. Angiuoli,T. Dickinson,Erin Hickey,Ingeborg Holt,Brendan J. Loftus,Fan Yang,Hamilton O. Smith,J. C. Venter,Brian Dougherty,Donald A. Morrison,S. K. Hollingshead,Claire M. Fraser +38 more
TL;DR: A motif identified within the signal peptide of proteins is potentially involved in targeting these proteins to the cell surface of low–guanine/cytosine Gram-positive species.
Journal ArticleDOI
Complete genome sequence and comparative analysis of the metabolically versatile Pseudomonas putida KT2440
Karen E. Nelson,Christian Weinel,Ian T. Paulsen,Robert J. Dodson,H. Hilbert,V. A. P. Martins Dos Santos,Derrick E. Fouts,Steven R. Gill,Mihai Pop,Mark A. Holmes,Lauren M. Brinkac,Maureen J. Beanan,Robert T. DeBoy,Sean C. Daugherty,James F. Kolonay,Ramana Madupu,William C. Nelson,Owen White,Jeremy Peterson,Hoda Khouri,Ioana R. Hance,P. Chris Lee,Erik Holtzapple,David J. Scanlan,Kevin Tran,A. Moazzez,T. Utterback,M. Rizzo,K. Lee,Daniel S. Kosack,D. Moestl,H. Wedler,J. Lauber,Diana Stjepandic,Jörg D. Hoheisel,M. Straetz,Sabina Heim,C. Kiewitz,Jonathan A. Eisen,Kenneth N. Timmis,A. Düsterhöft,Burkhard Tümmler,Claire M. Fraser +42 more
TL;DR: Pseudomonas putida is a metabolically versatile saprophytic soil bacterium that has been certified as a biosafety host for the cloning of foreign genes.
Journal ArticleDOI
The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria
Timothy D. Read,Timothy D. Read,Scott N. Peterson,Scott N. Peterson,Nicolas J. Tourasse,Les Baillie,Les Baillie,Ian T. Paulsen,Ian T. Paulsen,Karen E. Nelson,Hervé Tettelin,Derrick E. Fouts,Jonathan A. Eisen,Jonathan A. Eisen,Steven R. Gill,Erik Holtzapple,Ole Andreas Økstad,Erlendur Helgason,Jennifer Rilstone,Martin Wu,James F. Kolonay,Maureen J. Beanan,Robert J. Dodson,Lauren M. Brinkac,Michelle L. Gwinn,Robert T. DeBoy,Ramana Madpu,Sean C. Daugherty,A. Scott Durkin,Daniel H. Haft,William C. Nelson,Jeremy Peterson,Mihai Pop,Hoda Khouri,Diana Radune,Jonathan L. Benton,Yasmin Mahamoud,Lingxia Jiang,Ioana R. Hance,Janice Weidman,Kristi Berry,Roger D. Plaut,Alex M. Wolf,Kisha Watkins,William C. Nierman,Alyson Hazen,Robin T. Cline,Caroline Redmond,Joanne Elizabeth Thwaite,Owen White,Steven L. Salzberg,Steven L. Salzberg,Brendan Thomason,Arthur M. Friedlander,Theresa M. Koehler,Philip C. Hanna,Anne-Brit Kolstø,Claire M. Fraser,Claire M. Fraser +58 more
TL;DR: Several chromosomally encoded proteins that may contribute to pathogenicity—including haemolysins, phospholipases and iron acquisition functions—and numerous surface proteins that might be important targets for vaccines and drugs are found.
Journal ArticleDOI
Comparative Genome Sequencing for Discovery of Novel Polymorphisms in Bacillus anthracis
Timothy D. Read,Steven L. Salzberg,Mihai Pop,Martin Shumway,Lowell Umayam,Lingxia Jiang,Erik Holtzapple,Joseph D. Busch,Kimothy L. Smith,James M. Schupp,Daniel Solomon,Paul Keim,Claire M. Fraser +12 more
TL;DR: Comparison of the whole-genome sequence of Bacillus anthracis isolated from a victim of a recent bioterrorist anthrax attack with a reference reveals 60 new markers that include single nucleotide polymorphisms, inserted or deleted sequences, and tandem repeats.
Journal ArticleDOI
Genome sequence of Chlamydophila caviae (Chlamydia psittaci GPIC): examining the role of niche‐specific genes in the evolution of the Chlamydiaceae
Timothy D. Read,Garry S. A. Myers,Robert C. Brunham,William C. Nelson,Ian T. Paulsen,Ian T. Paulsen,John F. Heidelberg,Erik Holtzapple,Hoda Khouri,N. B. Federova,Heather A. Carty,Lowell Umayam,Daniel H. Haft,Jeremy Peterson,Maureen J. Beanan,Owen White,Steven L. Salzberg,Ru-ching Hsia,G. McClarty,Roger G. Rank,Patrik M. Bavoil,Claire M. Fraser,Claire M. Fraser +22 more
TL;DR: The genome of C.caviae was determined, representing the fourth species with a complete genome sequence from the Chlamydiaceae family of obligate intracellular bacterial pathogens, and enabling dissection of the roles played by niche-specific genes in these important bacterial pathogens.