E
Erina Furuhata
Publications - 10
Citations - 2403
Erina Furuhata is an academic researcher. The author has contributed to research in topics: DNA demethylation & DNA methylation. The author has an hindex of 4, co-authored 6 publications receiving 1979 citations.
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Journal ArticleDOI
An atlas of active enhancers across human cell types and tissues
Robin Andersson,Claudia Gebhard,Irene Miguel-Escalada,Ilka Hoof,Jette Bornholdt,Mette Boyd,Yun Chen,Xiaobei Zhao,Xiaobei Zhao,Christian Schmidl,Takahiro Suzuki,Evgenia Ntini,Erik Arner,Eivind Valen,Eivind Valen,Kang Li,Lucia Schwarzfischer,Dagmar Glatz,Johanna Raithel,Berit Lilje,Nicolas Rapin,Frederik Otzen Bagger,Mette Rose Jørgensen,Peter Refsing Andersen,Nicolas Bertin,Owen J. L. Rackham,A. Maxwell Burroughs,J Kenneth Baillie,Yuri Ishizu,Yuri Shimizu,Erina Furuhata,Shiori Maeda,Yutaka Negishi,Christopher J. Mungall,Terrence F. Meehan,Timo Lassmann,Masayoshi Itoh,Hideya Kawaji,Naoto Kondo,Jun Kawai,Andreas Lennartsson,Carsten O. Daub,Peter Heutink,David A. Hume,Torben Heick Jensen,Harukazu Suzuki,Yoshihide Hayashizaki,Ferenc Müller,Alistair R. R. Forrest,Piero Carninci,Michael Rehli,Albin Sandelin +51 more
TL;DR: It is shown that enhancers share properties with CpG-poor messenger RNA promoters but produce bidirectional, exosome-sensitive, relatively short unspliced RNAs, the generation of which is strongly related to enhancer activity.
Journal ArticleDOI
RUNX1 regulates site specificity of DNA demethylation by recruitment of DNA demethylation machineries in hematopoietic cells.
Takahiro Suzuki,Yuri Shimizu,Erina Furuhata,Shiori Maeda,Mami Kishima,Hajime Nishimura,Saaya Enomoto,Yoshihide Hayashizaki,Harukazu Suzuki +8 more
TL;DR: Zhang et al. as mentioned in this paper demonstrate that RUNX1 contributes DNA demethylation in a binding site-directed manner in human hematopoietic cells. But the role of the epigenetic role of runx1 remains unclear.
Journal ArticleDOI
A screening system to identify transcription factors that induce binding site-directed DNA demethylation
Takahiro Suzuki,Shiori Maeda,Erina Furuhata,Yuri Shimizu,Hajime Nishimura,Mami Kishima,Harukazu Suzuki +6 more
TL;DR: A screening system that involves the ectopic expression of target TFs in model cells followed by DNA methylome analysis and overrepresentation analysis of the corresponding TF binding motif at differentially methylated regions successfully identified binding site-directed demethylation of SPI1.
RUNX1 regulates site-specificity of DNA demethylation by recruitment of DNA demethylation machineries in hematopoietic cells
Takahiro Suzuki,Yuri Shimizu,Erina Furuhata,Shiori Maeda,Mami Kishima,Hajime Nishimura,Saaya Enomoto,Yoshihide Hayashizaki,Harukazu Suzuki +8 more
TL;DR: Evidence is provided that RUNX1 contributes site specificity of DNA dem methylation by recruitment of TET and other demethylation-related enzymes to its binding sites in hematopoietic cells.
Journal ArticleDOI
CpG site-specific alteration of hydroxymethylcytosine to methylcytosine beyond DNA replication.
Atsutaka Kubosaki,Yasuhiro Tomaru,Erina Furuhata,Takahiro Suzuki,Jay W. Shin,Christophe Simon,Yoshinari Ando,Ryota Hasegawa,Yoshihide Hayashizaki,Harukazu Suzuki +9 more
TL;DR: The results strongly suggest that somatic cells undergo hmC to mC specifically at the CpG sites during cell division, whereas the unmodified MoCEV did not undergo any DNA methylation during Cell division.