E
Ernst Bamberg
Researcher at Max Planck Society
Publications - 267
Citations - 26909
Ernst Bamberg is an academic researcher from Max Planck Society. The author has contributed to research in topics: Bacteriorhodopsin & Membrane. The author has an hindex of 74, co-authored 261 publications receiving 24745 citations. Previous affiliations of Ernst Bamberg include Moscow Institute of Physics and Technology & Free University of Berlin.
Papers
More filters
Journal ArticleDOI
Millisecond-timescale, genetically targeted optical control of neural activity.
TL;DR: In this paper, the authors adapted the naturally occurring algal protein Channelrhodopsin-2, a rapidly gated light-sensitive cation channel, by using lentiviral gene delivery in combination with high-speed optical switching to photostimulate mammalian neurons.
Journal ArticleDOI
Channelrhodopsin-2, a directly light-gated cation-selective membrane channel.
Georg Nagel,Tanjef Szellas,Wolfram Huhn,Suneel Kateriya,Nona Adeishvili,Peter Berthold,Doris Ollig,Peter Hegemann,Ernst Bamberg +8 more
TL;DR: It is demonstrated by functional expression, both in oocytes of Xenopus laevis and mammalian cells, that ChR2 is a directly light-switched cation-selective ion channel, and may be used to depolarize small or large cells, simply by illumination.
Journal ArticleDOI
Multimodal fast optical interrogation of neural circuitry
Feng Zhang,Liping Wang,Martin Brauner,Jana F. Liewald,Kenneth Kay,Natalie Watzke,Phillip G. Wood,Ernst Bamberg,Ernst Bamberg,Georg Nagel,Alexander Gottschalk,Karl Deisseroth +11 more
TL;DR: An archaeal light-driven chloride pump from Natronomonas pharaonis is identified and developed for temporally precise optical inhibition of neural activity and forms a complete system for multimodal, high-speed, genetically targeted, all-optical interrogation of living neural circuits.
Journal Article
Multimodal fast optical interrogation of neural circuitry
Feng Zhang,Liping Wang,Martin Brauner,Jana F. Liewald,Kenneth Kay,Natalie Watzke,Phillip G. Wood,Ernst Bamberg,Georg Nagel,Alexander Gottschalk,Karl Deisseroth +10 more
TL;DR: In this paper, an archaeal light-driven chloride pump (NpHR) was developed for temporally precise optical inhibition of neural activity, allowing either knockout of single action potentials, or sustained blockade of spiking.
Journal ArticleDOI
Channelrhodopsin-1: a light-gated proton channel in green algae.
Georg Nagel,Doris Ollig,Markus Fuhrmann,Suneel Kateriya,Anna Maria Musti,Ernst Bamberg,Peter Hegemann +6 more
TL;DR: A complementary DNA sequence in the green alga Chlamydomonas reinhardtiithat encodes a microbial opsin-related protein, which is suggested to be Channelopsin-1, which shows homology to the light-activated proton pump bacteriorhodopsin.