This 11th edition of the book Modern Nutrition in Health and Disease, featuring the work of more than 190 expert authors and divided into five parts, fully explains and encapsulates the fundamentals of nutrition and its role in contemporary society, from mastering the basic science of nutrient metabolism and function to applying nutritional concepts to combat human disease. Part I comprehensively covers specific dietary components, including major dietary constituents, minerals, vitamins and other Other CABI sites 

Modern Nutrition in Health and Disease

Renal osteodystrophy

Medical applications and biotechnological advances, including magnetic resonance imaging, cell separation and detection, tissue repair, magnetic hyperthermia and drug delivery, have strongly benefited from employing iron oxide nanoparticles (IONPs) due to their remarkable properties, such as superparamagnetism, size and possibility of receiving a biocompatible coating. Ongoing research efforts focus on reducing drug concentration, toxicity, and other side effects, while increasing efficacy of IONPs-based treatments. This review highlights the methods of synthesis and presents the most recent reports in the literature regarding advances in drug delivery using IONPs-based systems, as well as their antimicrobial activity against different microorganisms. Furthermore, the toxicity of IONPs alone and constituting nanosystems is also addressed.

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Iron Oxide Nanoparticles for Biomedical Applications: A Perspective on Synthesis, Drugs, Antimicrobial Activity, and Toxicity.

Preparation, surface functionalization and application of Fe3O4 magnetic nanoparticles.

Surface design of magnetic nanoparticles for stimuli-responsive cancer imaging and therapy.

Immobilization of albumin on magnetite nanoparticles

Interaction of donepezil with human serum albumin on amine-modified magnetic nanoparticles

Binding interactions of niclosamide with serum proteins

International Conference on Computational and Experimental Science and Engineering (ICCESEN) -- OCT 25-29, 2014 -- Antalya, TURKEY

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Evaluation of Antioxidant Activity, Phytochemicals and ESR Analysis of Lavandula Stoechas

Superparamagnetic iron oxide nanoparticles (SPIONs) were modified with [3-(2,3-epoxy-propoxy)propyl] trimethoxy silane, which resulted in formation of epoxy groups on the particles surface. The epoxy functionalized SPIONs can bind to human serum albumin (HSA). The binding amount of HSA to epoxy modified SPIONs was found to be as 32.7 microM for 1 mg epoxy modified SPIONs at 280 and 342 nm of excitation and emission wavelengths by using fluorescence spectroscopy. Interaction of ketoconazole with HSA immobilized epoxy functionalized SPIONs was studied at 300 and 390 nm of excitation and emission wavelengths, respectively. Binding mechanism of ketoconazole and HSA was identified by Stern-Volmer equation. Thermodynamic parameters (deltaH, deltaS and deltaG) were also estimated for the interaction. Therefore, the nature of the binding forces was found to be as hydrophobic interaction. Protein and drug attachments were also examined by Infrared spectroscopy (IR) and Scanning Electron Microscopy (SEM). This study show that prepared albumin-based magnetic nanoparticles carrier systems represents an attractive strategy for drug delivery.

Esra Maltas

Papers

Immobilization of albumin on magnetite nanoparticles

Interaction of donepezil with human serum albumin on amine-modified magnetic nanoparticles

Binding interactions of niclosamide with serum proteins

Evaluation of Antioxidant Activity, Phytochemicals and ESR Analysis of Lavandula Stoechas

Interaction between ketoconazole and human serum albumin on epoxy modified magnetic nanoparticles for drug delivery.