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Estefania Mancini
Researcher at Fundación Instituto Leloir
Publications - 25
Citations - 849
Estefania Mancini is an academic researcher from Fundación Instituto Leloir. The author has contributed to research in topics: RNA splicing & Alternative splicing. The author has an hindex of 11, co-authored 23 publications receiving 610 citations. Previous affiliations of Estefania Mancini include Pompeu Fabra University & Spanish National Research Council.
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Journal ArticleDOI
LNK genes integrate light and clock signaling networks at the core of the Arabidopsis oscillator
Matias Leandro Rugnone,Ana Faigon Soverna,Sabrina E. Sanchez,Ruben Gustavo Schlaen,Carlos Esteban Hernando,Danelle K. Seymour,Estefania Mancini,Ariel Chernomoretz,Detlef Weigel,Paloma Mas,Marcelo J. Yanovsky +10 more
TL;DR: A family of night light–inducible and clock-regulated genes (LNK) that play a key role linking light regulation of gene expression to the control of daily and seasonal rhythms in Arabidopsis thaliana are described.
Journal ArticleDOI
The Dengue Virus NS5 Protein Intrudes in the Cellular Spliceosome and Modulates Splicing
Federico Andres de Maio,Guillermo Risso,Nestor Gabriel Iglesias,Priya S. Shah,Berta Pozzi,Leopoldo German Gebhard,Pablo Mammi,Estefania Mancini,Marcelo J. Yanovsky,Raul Andino,Nevan J. Krogan,Anabella Srebrow,Andrea V. Gamarnik +12 more
TL;DR: A novel function of NS5 in the nucleus where it interferes with cellular splicing is demonstrated and it is proposed that NS5 binding to U5 snRNP proteins hijacks the splicing machinery resulting in a less restrictive environment for viral replication.
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The spliceosome assembly factor GEMIN2 attenuates the effects of temperature on alternative splicing and circadian rhythms
Ruben Gustavo Schlaen,Estefania Mancini,Sabrina E. Sanchez,Soledad Perez-Santángelo,Matias Leandro Rugnone,Craig G. Simpson,John W. S. Brown,Xu Zhang,Ariel Chernomoretz,Marcelo J. Yanovsky +9 more
TL;DR: GEMIN2, a spliceosomal small nuclear ribonucleoprotein assembly factor conserved from yeast to humans, modulates low temperature effects on a large subset of pre-mRNA splicing events, which controls the AS of several clock genes and attenuates the effects of temperature on the circadian period in Arabidopsis thaliana.
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Genome-wide annotation of the soybean WRKY family and functional characterization of genes involved in response to Phakopsora pachyrhizi infection
Marta Bencke-Malato,Caroline Cabreira,Beatriz Wiebke-Strohm,Lauro Bücker-Neto,Estefania Mancini,Marina Borges Osorio,Milena Schenkel Homrich,Andreia Carina Turchetto-Zolet,Mayra Costa da Cruz Gallo de Carvalho,Renata Stolf,Ricardo Luís Mayer Weber,Gaston Westergaard,Atilio Pedro Castagnaro,Ricardo Vilela Abdelnoor,Francismar Corrêa Marcelino-Guimarães,Márcia Margis-Pinheiro,Maria Helena Bodanese-Zanettini +16 more
TL;DR: A genome-wide annotation of soybean WRKY family was carried out and the participation of some members in response to P. pachyrhizi infection was demonstrated, suggesting the manipulation of WRKYs as a strategy to increase fungal resistance in soybean plants.
Journal ArticleDOI
Role for LSM genes in the regulation of circadian rhythms
Soledad Perez-Santángelo,Estefania Mancini,Lauren J. Francey,Ruben Gustavo Schlaen,Ariel Chernomoretz,John B. Hogenesch,Marcelo J. Yanovsky +6 more
TL;DR: It is shown that SM-like (LSM) genes, which encode core components of the spliceosome, are regulated by the circadian clock and control clock function in plants and mammals, revealing convergent evolutionary mechanisms mediating posttranscriptional regulation of circadian networks across kingdoms.