E
Ester Pagano
Researcher at University of Naples Federico II
Publications - 55
Citations - 2108
Ester Pagano is an academic researcher from University of Naples Federico II. The author has contributed to research in topics: Cannabinoid receptor & Medicine. The author has an hindex of 21, co-authored 48 publications receiving 1473 citations. Previous affiliations of Ester Pagano include University of Salerno & University of Cambridge.
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Journal ArticleDOI
Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease
Francesca Borrelli,Ines Fasolino,Barbara Romano,Raffaele Capasso,Francesco Maiello,Diana Coppola,Pierangelo Orlando,Giovanni Battista,Ester Pagano,Vincenzo Di Marzo,Angelo A. Izzo +10 more
TL;DR: Cannabigerol attenuated murine colitis, reduced nitric oxide production in macrophages (effect being modulated by the CB2 receptor) and reduced ROS formation in intestinal epithelial cells, and could be considered for clinical experimentation in IBD patients.
Journal ArticleDOI
Novel insights into the pharmacology of flavonoids.
Barbara Romano,Ester Pagano,Vittorino Montanaro,Alfonso L. Fortunato,Natasa Milic,Francesca Borrelli +5 more
TL;DR: The most recent developments in flavonoid – and related polyphenolic compounds – pharmacology are discussed, with particular emphasis on very recent data, most of which are published in Phytotherapy Research, which highlight new aspects.
Journal ArticleDOI
Colon carcinogenesis is inhibited by the TRPM8 antagonist cannabigerol, a Cannabis-derived non-psychotropic cannabinoid
Francesca Borrelli,Ester Pagano,Barbara Romano,Stefania Panzera,Francesco Maiello,Diana Coppola,Luciano De Petrocellis,Lorena Buono,Pierangelo Orlando,Angelo A. Izzo +9 more
TL;DR: In vivo, CBG hampers colon cancer progression in vivo and selectively inhibits the growth of CRC cells, an effect shared by other TRPM8 antagonists, and should be considered translationally in CRC prevention and cure.
Journal ArticleDOI
Palmitoylethanolamide, a naturally occurring lipid, is an orally effective intestinal anti-inflammatory agent.
Francesca Borrelli,Barbara Romano,Stefania Petrosino,Ester Pagano,Raffaele Capasso,Diana Coppola,Giovanni Battista,Pierangelo Orlando,Vincenzo Di Marzo,Angelo A. Izzo +9 more
TL;DR: The effect of PEA is investigated in a murine model of colitis by studying its role in the regulation of intestinal inflammation through modulation of G protein‐coupled receptor 55.
Journal ArticleDOI
An Orally Active Cannabis Extract with High Content in Cannabidiol attenuates Chemically-induced Intestinal Inflammation and Hypermotility in the Mouse
Ester Pagano,Raffaele Capasso,Raffaele Capasso,Fabiana Piscitelli,Barbara Romano,Barbara Romano,Olga A. Parisi,Stefania Finizio,Anna Lauritano,Vincenzo Di Marzo,Angelo Antonio Izzo,Angelo Antonio Izzo,Francesca Borrelli,Francesca Borrelli +13 more
TL;DR: CBD BDS, given after the inflammatory insult, attenuates injury and motility in intestinal models of inflammation and sustain the rationale of combining CBD with other minor Cannabis constituents and support the clinical development of CBD BDS for IBD treatment.