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Ethan S Srinivasan
Researcher at Duke University
Publications - 28
Citations - 135
Ethan S Srinivasan is an academic researcher from Duke University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 2, co-authored 10 publications receiving 14 citations.
Papers
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Journal ArticleDOI
CD4 T-Cell Exhaustion: Does It Exist and What Are Its Roles in Cancer?
Alexandra M. Miggelbrink,Joshua D. Jackson,Selena J. Lorrey,Ethan S Srinivasan,Jessica Waibl-Polania,Daniel Wilkinson,Peter E. Fecci +6 more
TL;DR: In this paper, the authors discuss mechanistic and clinical evidence for CD4 T-cell exhaustion in cancer and reveal novel therapeutic targets to abrogate CD4T-cell depletion in cancer.
Journal ArticleDOI
The intersection between immunotherapy and laser interstitial thermal therapy: a multipronged future of neuro-oncology.
Ethan S Srinivasan,Eric W. Sankey,Matthew M. Grabowski,Pakawat Chongsathidkiet,Peter E. Fecci +4 more
TL;DR: The wide-ranging immunomodulatory effects of localized and whole-body HT have been investigated and have demonstrated immunostimulatory effects at the level of tumor cells, immune cells, and the broader environment governing potential immune surveillance.
Journal ArticleDOI
Time to Steroid Independence After Laser Interstitial Thermal Therapy vs Medical Management for Treatment of Biopsy-Proven Radiation Necrosis Secondary to Stereotactic Radiosurgery for Brain Metastasis
Eric W. Sankey,Matthew M. Grabowski,Ethan S Srinivasan,Andrew S. Griffin,Elizabeth P. Howell,Balint Otvos,Vadim Tsvankin,Gene H. Barnett,Alireza M. Mohammadi,Peter E. Fecci +9 more
TL;DR: LITT for treatment of biopsy-proven RN after SRS for BM significantly decreases time to steroid independence, and Prospective trials should be designed to further validate the utility of LITT for RN and its impact on steroid-induced morbidity.
Journal ArticleDOI
Salting the Soil: Targeting the Microenvironment of Brain Metastases.
Ethan S Srinivasan,Aaron Tan,Carey K. Anders,Ann Marie Pendergast,Dorothy A. Sipkins,David M. Ashley,Peter E. Fecci,Mustafa Khasraw +7 more
TL;DR: A review of the general and specific pathways for brain metastases and related work in glioma is presented in this paper, which identifies targetable mechanisms that may have general application across the spectrum of intracranial tumors.
Book ChapterDOI
Laser interstitial thermal therapy for brain metastases.
TL;DR: This chapter reviews the current literature on the role of LITT in treatment of brain metastases and discusses its role in treating this difficult entity.