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Eugene Braunwald
Researcher at Brigham and Women's Hospital
Publications - 1758
Citations - 278949
Eugene Braunwald is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Myocardial infarction & TIMI. The author has an hindex of 230, co-authored 1711 publications receiving 264576 citations. Previous affiliations of Eugene Braunwald include Boston University & University of California, San Francisco.
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Early and late benefits of prasugrel in patients with acute coronary syndromes undergoing percutaneous coronary intervention: a TRITON-TIMI 38 (TRial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet InhibitioN with Prasugrel-Thrombolysis In Myocardial Infarction) analysis.
Elliott M. Antman,Stephen D. Wiviott,Sabina A. Murphy,Juri Voitk,Yonathan Hasin,Petr Widimsky,Harish Chandna,William L. Macias,Carolyn H. McCabe,Eugene Braunwald +9 more
TL;DR: Both the loading dose and maintenance dose of prasugrel were superior to clopidogrel for the reduction of ischemic events in a TRITON-TIMI 38 analysis, emphasizing the importance of maintaining high levels of inhibition of platelet aggregation via P2Y(12) receptor inhibition during long-term follow-up.
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Studies on Digitalis. X. Effects of Ouabain on Forearm Vascular Resistance and Venous Tone in Normal Subjects and in Patients in Heart Failure
TL;DR: The present investigation was undertaken to characterize the effects of ouabain on a specific vascular bed, that of the forearm, which was examined in normal subjects and in patients with congestive heart failure.
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Modification of myocardial infarction size after coronary occlusion.
Peter R. Maroko,Eugene Braunwald +1 more
TL;DR: Several pharmacologic and hemodynamic interventions were found to alter acute ischemic injury of the myocardium and subsequent necrosis after coronary occlusion and reduction in myocardial thickness was found.
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Can low-density lipoprotein be too low? The safety and efficacy of achieving very low low-density lipoprotein with intensive statin therapy: a PROVE IT-TIMI 22 substudy.
Stephen D. Wiviott,Christopher P. Cannon,David A. Morrow,Kausik K. Ray,Marc A. Pfeffer,Eugene Braunwald,Prove It-Timi Investigators +6 more
TL;DR: In this article, the authors evaluated the safety and efficacy of achieving very low calculated low-density lipoprotein (LDL) levels with intensive statin therapy and found no adverse effect on safety with lower achieved LDL levels, and apparent improved clinical efficacy.
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Effect of Glucose-Insulin-Potassium Infusion on Myocardial Infarction following Experimental Coronary Artery Occlusion
Peter R. Maroko,Peter Libby,Burton E. Sobel,Colin M. Bloor,H. D. Sybers,William E. Shell,James W. Covell,Eugene Braunwald +7 more
TL;DR: GIK exerts a protective effect against myocardial ischemia and reduces the extent ofMyocardial necrosis, while a beneficial effect can also be demonstrated when GIK and P are started 3 hours after the onset of coronary occlusion.