Eugene Braunwald

TL;DR: This review focuses on four interrelated roles for ST segment monitoring: the assessment of epicardial reperfusion and the identification of candidates for rescue percutaneous coronary intervention; the evaluation of microvascular and tissue-level reperFusion; the determination of prognosis early after fibrinolytic therapy; and the use of ST segment resolution to compare different reperfusions regimens.

TL;DR: Pharmacological doses of hydrocortisone prevent myocardial cells from progressing to ischemic necrosis even when administration is initiated 6 h after coronary occlusion, showing that over one third of the sites were protected from undergoing necrosis due to the intervening hydroc Cortisone treatment.

TL;DR: The results do not support use of oral iron supplementation in patients with HFrEF and iron deficiency, and high-dose oral iron did not improve exercise capacity over 16 weeks.

TL;DR: Fixed-dose orbofiban failed to reduce major cardiovascular events and was associated with increased mortality in this broad population of patients with acute coronary syndromes; however, a benefit was observed among patients who underwent percutaneous coronary intervention.

TL;DR: In patients with stable CAD, high-sensitivity cardiac troponin I concentrations are associated with cardiovascular risk independently of conventional risk markers and hs-TnT.