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Eugene Ng

Bio: Eugene Ng is an academic researcher from Sunnybrook Health Sciences Centre. The author has contributed to research in topics: Machining & Chip formation. The author has an hindex of 28, co-authored 74 publications receiving 3118 citations. Previous affiliations of Eugene Ng include University of Birmingham & University of Toronto.


Papers
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Journal ArticleDOI
Karel O'Brien1, Karel O'Brien2, Kate Robson3, Marianne Bracht, Melinda Cruz, Kei Lui4, Ruben Alvaro5, Orlando da Silva6, Luis Monterrosa7, Michael Narvey5, Eugene Ng3, Eugene Ng1, Amuchou Soraisham8, Amuchou Soraisham9, Xiang Y. Ye2, Lucia Mirea10, Lucia Mirea1, William Tarnow-Mordi11, Shoo K. Lee, Shoo K. Lee1, Georges Caouette, Douglas McMillan, Linh Ly, Kimberly Dow, Richard Taylor, Roderick Canning, Koravangattu Sankaran, William Bingham, Salhab el Helos, Horacio Osiovich, Julie Emberley, Celine Catelin, Lucia St. Aubin, Tammy Warkentin, Zarin Kalapesi, Jaya Bodani, Guan Kho, Zsuzsoka Kecskes, Jacqueline Stack, Peter Schmidt, Mary Paradisis, Roland S. Broadbent, Clare Raiman, Charlene A. Wong, Michele Cabot, Maryse L'Herault, Marie-Andree Gignac, Marie-Helene Marquis, Mylene Leblanc, Cathy Travell, Marlene Furlong, Annette Van Bergen, Maryanne Ottenhof, Heather Keron, Clare Bowley, Shannon Cross, Gillian Kozinka, Valerie Cobham-Richards, Kelly Northrup, Cindy Gilbert-Rogers, Pat Pidgeon, Kim McDuff, Norma Leger, Cindy Thiel, Shannon Willard, Evelyn Ma, Linda Kostecky, David Pogorzelski, Sherin Jacob, Kim Kwiatkowski, Valerie Cook, Naomi Granke, Nicola Geoghegan-Morphet, Hannah Bowell, Jennifer Claydon, Nicole Tucker, Thomas Lemaitre, Myriam Doyon, Candace Ryan, Joanne Sheils, Elizabeth Sibbons, Anne-Marie Feary, Ian Callander, Robyn Richard, Jennifer Orbeso, Margaret Broom, Alexis Fox, Jan Seuseu, Jack Hourigan, Cynthia Schaeffer, Ginette Mantha, Melanie Lataigne, Leah Whitehead, Natasha Skinner, Rita Visconti, Deedee Crosland, Kate Griffin, Brandon Griffin, Lisa Collins, Kirsten Meyer, Ian Silver, Britt Burnham, Rachel Freeman, Kristi Muralt, Cara Ramsay, Pawulina McGrath, Michelle Munroe, Denise Hales 
TL;DR: FICare improved infant weight gain, decreased parent stress and anxiety, and increased high-frequency exclusive breastmilk feeding at discharge, which together suggest that FICare is an important advancement in neonatal care.

287 citations

Journal ArticleDOI
TL;DR: In this article, the effects of cutting-edge radius on residual stresses (R.S) were investigated in orthogonal dry cutting austenitic stainless steel AISI 316L with continuous chip formation.
Abstract: Tool-edge geometry has significant effects on the cutting process, as it affects cutting forces, stresses, temperatures, deformation zone, and surface integrity. An Arbitrary-Lagrangian–Eulerian (A.L.E.) finite element model is presented here to simulate the effects of cutting-edge radius on residual stresses (R.S.) when orthogonal dry cutting austenitic stainless steel AISI 316L with continuous chip formation. Four radii were simulated starting with a sharp edge, with a finite radius, and up to a value equal to the uncut chip thickness. Residual stress profiles started with surface tensile stresses then turned to be compressive at about 140 μm from the surface; the same trend was found experimentally. Larger edge radius induced higher R.S. in both the tensile and compressive regions, while it had almost no effect on the thickness of tensile layer and pushed the maximum compressive stresses deeper into the workpiece. A stagnation zone was clearly observed when using non-sharp tools and its size increased with edge radius. The distance between the stagnation-zone tip and the machined surface increased with edge radius, which explained the increase in material plastic deformation, and compressive R.S. when using larger edge radius. Workpiece temperatures increased with edge radius; this is attributed to the increase in friction heat generation as the contact area between the tool edge and workpiece increases. Consequently, higher tensile R.S. were induced in the near-surface layer. The low thermal conductivity of AISI 316L restricted the effect of friction heat to the near-surface layer; therefore, the thickness of tensile layer was not affected.

206 citations

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TL;DR: In this article, the results of application of different coolant strategies to high-speed milling of aluminum alloy A356 for automotive industry were described and the effect of flood coolant, dry cutting, and minimum quantity of lubricant (MQL) technologies on tool wear, surface roughness and cutting forces were investigated.
Abstract: This paper describes the results of application of different coolant strategies to high-speed milling of aluminum alloy A356 for automotive industry. The paper investigates the effect of flood coolant, dry cutting, and minimum quantity of lubricant (MQL) technologies on tool wear, surface roughness and cutting forces. The cutting speed range was up to 5225 m/min. The feed rate used was up to 20 m/min. The result of MQL application is compared with dry milling and milling with flood coolant application. It was found that the MQL technology could be a viable alternative to the flood coolant application. The adhesive tool wear mechanism and adhesion activated surface quality deterioration are revealed and the role of lubricant in their reduction is defined.

201 citations

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TL;DR: In this article, an elasto-plastic finite element (FE) model is presented to simulate the erosion process in 3D configuration, which takes into account numerical and material damping, thermal elasticplastic material behavior and the effect of multiple particle impacts as well as material removal.
Abstract: Material damage caused by the attack of particles entrained in a fluid system impacting a surface at high speed is called ‘Erosion’. Erosion is a phenomenon that takes place in several engineering applications. It also can be used in several manufacturing process such as abrasive waterjet machining. Erosion is a complex process dependent on particle speed, size, angle of attack as well as the behavior of the eroded material. Extensive experimental results have been reported in the literature on the erosion of different materials. Simulating the erosion process through finite element enables the prediction of erosion behavior of materials under different conditions, which will substitute the need of experimentation, and will enable the identification of constants required for existing analytical models. In this paper, an elasto-plastic finite element (FE) model is presented to simulate the erosion process in 3D configuration. The FE model takes into account numerical and material damping, thermal elastic–plastic material behavior and the effect of multiple particle impacts as well as material removal. The workpiece material modeled was Ti–6Al–4V. The effects of strain hardening, strain rate and temperature were considered in the non-linear material model. Comparison against results reported in literature and erosion models by Finnie, Bitter and Hashish are made. It is shown that the predicted results are in agreement with published results obtained experimentally and from analytical erosion models.

178 citations

Journal ArticleDOI
TL;DR: The effectiveness of midazolam as a sedative in this population could not be ascertained based on the findings of these two studies, since the sedation scales used in both studies have not been validated in preterm infants.
Abstract: Background Proper sedation for neonates undergoing uncomfortable procedures may reduce stress and avoid complications. Midazolam is a short-acting benzodiazepine that is used increasingly in neonatal intensive care units (NICUs). However, its effectiveness as a sedative in neonates has not been systematically evaluated. Objectives Primary objecive To assess the effectiveness of intravenous midazolam infusion for sedation, as evaluated by behavioural and/or physiological measurements of sedation levels, in critically ill neonates in the NICU. Secondary objectives To assess effects of intravenous midazolam infusion for sedation on complications including the following. 1. Incidence of intraventricular haemorrhage (IVH)/periventricular leukomalacia (PVL). 2. Mortality. 3. Occurrence of adverse effects associated with the use of midazolam (hypotension, neurological abnormalities). 4. Days of ventilation. 5. Days of supplemental oxygen. 6. Incidence of pneumothorax. 7. Length of NICU stay (days). 8. Long-term neurodevelopmental outcomes. Search methods We used the standard search strategy of the Cochrane Neonatal Review Group to search the Cochrane Central Register of Controlled Trials (CENTRAL; 2016, Issue 5), MEDLINE via PubMed (1966 to 16 June 2016), Embase (1980 to 16 June 2016) and the Cumulative Index to Nursing and Allied Health Literature (CINAHL; 1982 to 16 June 2016). We searched clinical trials databases, conference proceedings and reference lists of retrieved articles for randomised controlled trials and quasi-randomised trials. Selection criteria We selected for review randomised and quasi-randomised controlled trials of intravenous midazolam infusion for sedation in infants aged 28 days or younger. Data collection and analysis We abstracted data regarding the primary outcome of level of sedation. We assessed secondary outcomes such as intraventricular haemorrhage, periventricular leukomalacia, death, length of NICU stay and adverse effects associated with midazolam. When appropriate, we performed meta-analyses using risk ratios (RRs) and risk differences (RDs), and if the RD was statistically significant, we calculated the number needed to treat for an additional beneficial outcome (NNTB) or an additional harmful outcome (NNTH), along with their 95% confidence intervals (95% CIs) for categorical variables, and weighted mean differences (WMDs) for continuous variables. We assessed heterogeneity by performing the I-squared (I2) test. Main results We included in the review three trials enrolling 148 neonates. We identified no new trials for this update. Using different sedation scales, each study showed a statistically significantly higher sedation level in the midazolam group compared with the placebo group. However, none of the sedation scales used have been validated in preterm infants; therefore, we could not ascertain the effectiveness of midazolam in this population. Duration of NICU stay was significantly longer in the midazolam group than in the placebo group (WMD 5.4 days, 95% CI 0.40 to 10.5; I2 = 0%; two studies, 89 infants). One study (43 infants) reported significantly lower Premature Infant Pain Profile (PIPP) scores during midazolam infusion than during dextrose (placebo) infusion (MD -3.80, 95% CI -5.93 to -1.67). Another study (46 infants) observed a higher incidence of adverse neurological events at 28 days' postnatal age (death, grade III or IV IVH or PVL) in the midazolam group compared with the morphine group (RR 7.64, 95% CI 1.02 to 57.21; RD 0.28, 95% CI 0.07 to 0.49; NNTH 4, 95% CI 2 to 14) (tests for heterogeneity not applicable). We considered these trials to be of moderate quality according to GRADE assessment based on the following outcomes: mortality during hospital stay, length of NICU stay, adequacy of analgesia according to PIPP scores and poor neurological outcomes by 28 days' postnatal age. Authors' conclusions Data are insufficient to promote the use of intravenous midazolam infusion as a sedative for neonates undergoing intensive care. This review raises concerns about the safety of midazolam in neonates. Further research on the effectiveness and safety of midazolam in neonates is needed.

176 citations


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TL;DR: In this paper, the authors provide an overview of machining induced surface integrity in titanium and nickel alloys and conclude that further modeling studies are needed to create predictive physics-based models that is in good agreement with reliable experiments.
Abstract: Titanium and nickel alloys represent a significant metal portion of the aircraft structural and engine components. When these critical structural components in aerospace industry are manufactured with the objective to reach high reliability levels, surface integrity is one of the most relevant parameters used for evaluating the quality of finish machined surfaces. The residual stresses and surface alteration (white etch layer and depth of work hardening) induced by machining of titanium alloys and nickel-based alloys are very critical due to safety and sustainability concerns. This review paper provides an overview of machining induced surface integrity in titanium and nickel alloys. There are many different types of surface integrity problems reported in literature, and among these, residual stresses, white layer and work hardening layers, as well as microstructural alterations can be studied in order to improve surface qualities of end products. Many parameters affect the surface quality of workpieces, and cutting speed, feed rate, depth of cut, tool geometry and preparation, tool wear, and workpiece properties are among the most important ones worth to investigate. Experimental and empirical studies as well as analytical and Finite Element modeling based approaches are offered in order to better understand machining induced surface integrity. In the current state-of-the-art however, a comprehensive and systematic modeling approach based on the process physics and applicable to the industrial processes is still missing. It is concluded that further modeling studies are needed to create predictive physics-based models that is in good agreement with reliable experiments, while explaining the effects of many parameters, for machining of titanium alloys and nickel-based alloys.

986 citations

Journal ArticleDOI
TL;DR: In this paper, the authors present an overview of recent trends and new concepts in the development of sustainable products, processes and systems, focusing on dry, near-dry and cryogenic machining as examples.
Abstract: Achieving sustainability in manufacturing requires a holistic view spanning not just the product, and the manufacturing processes involved in its fabrication, but also the entire supply chain, including the manufacturing systems across multiple product life-cycles. This requires improved models, metrics for sustainability evaluation, and optimization techniques at the product, process, and system levels. This paper presents an overview of recent trends and new concepts in the development of sustainable products, processes and systems. In particular, recent trends in developing improved sustainability scoring methods for products and processes, and predictive models and optimization techniques for sustainable manufacturing processes, focusing on dry, near-dry and cryogenic machining as examples, are presented.

801 citations

Journal ArticleDOI
TL;DR: A three-year study by the CIRP's Collaborative Working Group on Surface Integrity and Functional Performance of Components as discussed by the authors reported recent progress in experimental and theoretical investigations on surface integrity in material removal processes.

769 citations

Journal ArticleDOI
TL;DR: Evidence-based guidelines for preventing or treating neonatal pain and its adverse consequences are developed and management of pain must be considered an important component of the health care provided to all neonates, regardless of their gestational age or severity of illness.
Abstract: Objective To develop evidence-based guidelines for preventing or treating neonatal pain and its adverse consequences. Compared with older children and adults, neonates are more sensitive to pain and vulnerable to its long-term effects. Despite the clinical importance of neonatal pain, current medical practices continue to expose infants to repetitive, acute, or prolonged pain. Design Experts representing several different countries, professional disciplines, and practice settings used systematic reviews, data synthesis, and open discussion to develop a consensus on clinical practices that were supported by published evidence or were commonly used, the latter based on extrapolation of evidence from older age groups. A practical format was used to describe the analgesic management for specific invasive procedures and for ongoing pain in neonates. Results Recognition of the sources of pain and routine assessments of neonatal pain should dictate the avoidance of recurrent painful stimuli and the use of specific environmental, behavioral, and pharmacological interventions. Individualized care plans and analgesic protocols for specific clinical situations, patients, and health care settings can be developed from these guidelines. By clearly outlining areas where evidence is not available, these guidelines may also stimulate further research. To use the recommended therapeutic approaches, clinicians must be familiar with their adverse effects and the potential for drug interactions. Conclusion Management of pain must be considered an important component of the health care provided to all neonates, regardless of their gestational age or severity of illness.

743 citations

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TL;DR: The fourth update of “European Guidelines for the Management of RDS” by a European panel of experienced neonatologists and an expert perinatal obstetrician based on available literature up to the end of 2018 is reported.
Abstract: As management of respiratory distress syndrome (RDS) advances, clinicians must continually revise their current practice. We report the fourth update of “European Guidelines for the Management of RDS” by a European panel of experienced neonatologists and an expert perinatal obstetrician based on available literature up to the end of 2018. Optimising outcome for babies with RDS includes prediction of risk of preterm delivery, need for appropriate maternal transfer to a perinatal centre and timely use of antenatal steroids. Delivery room management has become more evidence-based, and protocols for lung protection including initiation of CPAP and titration of oxygen should be implemented immediately after birth. Surfactant replacement therapy is a crucial part of management of RDS, and newer protocols for its use recommend early administration and avoidance of mechanical ventilation. Methods of maintaining babies on non-invasive respiratory support have been further developed and may cause less distress and reduce chronic lung disease. As technology for delivering mechanical ventilation improves, the risk of causing lung injury should decrease, although minimising time spent on mechanical ventilation using caffeine and, if necessary, postnatal steroids are also important considerations. Protocols for optimising general care of infants with RDS are also essential with good temperature control, careful fluid and nutritional management, maintenance of perfusion and judicious use of antibiotics all being important determinants of best outcome.

732 citations