E
Eva Balint
Researcher at University of Massachusetts Medical School
Publications - 9
Citations - 3469
Eva Balint is an academic researcher from University of Massachusetts Medical School. The author has contributed to research in topics: Osteoblast & Replication protein A. The author has an hindex of 5, co-authored 7 publications receiving 3348 citations.
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Journal ArticleDOI
A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA.
Gyorgy Hutvagner,Juanita Mclachlan,Amy E. Pasquinelli,Eva Balint,Thomas Tuschl,Phillip D. Zamore +5 more
TL;DR: In Drosophila melanogaster a developmentally regulated precursor RNA is cleaved by an RNA interference-like mechanism to produce mature let-7 stRNA, which regulates developmental timing in Caenorhabditis elegans and probably in other bilateral animals.
Journal ArticleDOI
Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development.
Je-Yong Choi,Je-Yong Choi,Jitesh Pratap,Amjad Javed,S. Kaleem Zaidi,Lianping Xing,Eva Balint,Sara Dalamangas,Brendan F. Boyce,Andre J. van Wijnen,Jane B. Lian,Janet L. Stein,Stephen N. Jones,Gary S. Stein +13 more
TL;DR: It is concluded that subnuclear localization of Runx factors in specific foci together with associated regulatory functions is essential for control of RunX-dependent genes involved in tissue differentiation during embryonic development.
Journal ArticleDOI
Phenotype discovery by gene expression profiling: mapping of biological processes linked to BMP-2-mediated osteoblast differentiation.
Eva Balint,David S. Lapointe,Hicham Drissi,Caroline M. J. van der Meijden,Daniel W. Young,Andre J. Van Wijnen,Janet L. Stein,Gary S. Stein,Jane B. Lian +8 more
TL;DR: A global analysis identified a multistage molecular and cellular cascade that supports BMP‐2‐mediated osteoblast differentiation and resulted in the discovery of a class of genes, initially described in relation to differentiation of astrocytes and oligodendrocyte that are functionally coupled to signals for cellular extensions.
Journal ArticleDOI
Runx1/AML1 hematopoietic transcription factor contributes to skeletal development in vivo.
Jane B. Lian,Eva Balint,Amjad Javed,Hicham Drissi,Regan Vitti,Edward J. Quinlan,Lina Zhang,Andre J. Van Wijnen,Janet L. Stein,Nancy A. Speck,Gary S. Stein +10 more
TL;DR: In this article, the expression of Runx1 (AML1/Cbfa2) in relation to skeletal development using a LacZ knock-in mouse model (Runx1(lz/+) was investigated.