E
Evan W. Alley
Researcher at Johns Hopkins University
Publications - 2
Citations - 1226
Evan W. Alley is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Promoter & Luciferase. The author has an hindex of 2, co-authored 2 publications receiving 1212 citations.
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Journal ArticleDOI
Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon gamma and lipopolysaccharide
Charles J. Lowenstein,Evan W. Alley,Prafulla Raval,Adele M. Snowman,Solomon H. Snyder,Stephen W. Russell,William J. Murphy +6 more
TL;DR: Delineation of these two cooperative regions explains at the level of transcription how IFN-gamma and LPS act in concert to induce maximally the mac-NOS gene and, furthermore, howIFN-Gamma augments the inflammatory response to LPS.
Journal ArticleDOI
Progesterone inhibits inducible nitric oxide synthase gene expression and nitric oxide production in murine macrophages
TL;DR: Observations suggest that P4‐mediated inhibition of NO may be an important gender‐based difference within females and males that relates to macrophage‐mediated host defense.