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Evelina Sjöstedt
Researcher at Karolinska Institutet
Publications - 32
Citations - 18386
Evelina Sjöstedt is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Gene & Transcriptome. The author has an hindex of 16, co-authored 25 publications receiving 12362 citations. Previous affiliations of Evelina Sjöstedt include Royal Institute of Technology & Science for Life Laboratory.
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Journal ArticleDOI
Tissue-based map of the human proteome
Mathias Uhlén,Mathias Uhlén,Linn Fagerberg,Björn M. Hallström,Cecilia Lindskog,Per Oksvold,Adil Mardinoglu,Åsa Sivertsson,Caroline Kampf,Evelina Sjöstedt,Evelina Sjöstedt,Anna Asplund,IngMarie Olsson,Karolina Edlund,Emma Lundberg,Sanjay Navani,Cristina Al-Khalili Szigyarto,Jacob Odeberg,Dijana Djureinovic,Jenny Ottosson Takanen,Sophia Hober,Tove Alm,Per-Henrik Edqvist,Holger Berling,Hanna Tegel,Jan Mulder,Johan Rockberg,Peter Nilsson,Jochen M. Schwenk,Marica Hamsten,Kalle von Feilitzen,Mattias Forsberg,Lukas Persson,Fredric Johansson,Martin Zwahlen,Gunnar von Heijne,Jens Nielsen,Jens Nielsen,Fredrik Pontén +38 more
TL;DR: In this paper, a map of the human tissue proteome based on an integrated omics approach that involves quantitative transcriptomics at the tissue and organ level, combined with tissue microarray-based immunohistochemistry, to achieve spatial localization of proteins down to the single-cell level.
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Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics
Linn Fagerberg,Björn M. Hallström,Per Oksvold,Caroline Kampf,Dijana Djureinovic,Jacob Odeberg,Masato Habuka,Simin Tahmasebpoor,Angelika Danielsson,Karolina Edlund,Anna Asplund,Evelina Sjöstedt,Emma Lundberg,Cristina Al-Khalili Szigyarto,Marie Skogs,Jenny Ottosson Takanen,Holger Berling,Hanna Tegel,Jan Mulder,Peter Nilsson,Jochen M. Schwenk,Cecilia Lindskog,Frida Danielsson,Adil Mardinoglu,Åsa Sivertsson,Kalle von Feilitzen,Mattias Forsberg,Martin Zwahlen,IngMarie Olsson,Sanjay Navani,Mikael Huss,Jens Nielsen,Jens Nielsen,Fredrik Pontén,Mathias Uhlén +34 more
TL;DR: A quantitative transcriptomics analysis (RNA-Seq) is used to classify the tissue-specific expression of genes across a representative set of all major human organs and tissues and combined this analysis with antibody-based profiling of the same tissues.
Journal ArticleDOI
A pathology atlas of the human cancer transcriptome
Mathias Uhlén,Mathias Uhlén,Cheng Zhang,Sunjae Lee,Evelina Sjöstedt,Evelina Sjöstedt,Linn Fagerberg,Gholamreza Bidkhori,Rui Benfeitas,Muhammad Arif,Zhengtao Liu,Fredrik Edfors,Kemal Sanli,Kalle von Feilitzen,Per Oksvold,Emma Lundberg,Sophia Hober,Peter Nilsson,Johanna Sofia Margareta Mattsson,Jochen M. Schwenk,Hans Brunnström,Bengt Glimelius,Tobias Sjöblom,Per-Henrik Edqvist,Dijana Djureinovic,Patrick Micke,Cecilia Lindskog,Adil Mardinoglu,Adil Mardinoglu,Fredrik Pontén +29 more
TL;DR: A Human Pathology Atlas has been created as part of the Human Protein Atlas program to explore the prognostic role of each protein-coding gene in 17 different cancers, and reveals that gene expression of individual tumors within a particular cancer varied considerably and could exceed the variation observed between distinct cancer types.
Journal ArticleDOI
A subcellular map of the human proteome
Peter Thul,Lovisa Åkesson,Mikaela Wiking,Diana Mahdessian,Aikaterini Geladaki,Hammou Ait Blal,Tove Alm,Anna Asplund,Lars Björk,Lisa M. Breckels,Anna Bäckström,Frida Danielsson,Linn Fagerberg,Jenny Fall,Laurent Gatto,Christian Gnann,Sophia Hober,Martin Hjelmare,Fredric Johansson,Sunjae Lee,Cecilia Lindskog,Jan Mulder,Claire M. Mulvey,Peter Nilsson,Per Oksvold,Johan Rockberg,Rutger Schutten,Jochen M. Schwenk,Åsa Sivertsson,Evelina Sjöstedt,Marie Skogs,Charlotte Stadler,Devin P. Sullivan,Hanna Tegel,Casper F. Winsnes,Cheng Zhang,Martin Zwahlen,Adil Mardinoglu,Fredrik Pontén,Kalle von Feilitzen,Kathryn S. Lilley,Mathias Uhlén,Emma Lundberg +42 more
TL;DR: A subcellular map of the human proteome is presented to facilitate functional exploration of individual proteins and their role in human biology and disease and integrated into existing network models of protein-protein interactions for increased accuracy.
Journal ArticleDOI
An atlas of the protein-coding genes in the human, pig, and mouse brain
Evelina Sjöstedt,Evelina Sjöstedt,Wen Zhong,Linn Fagerberg,Max J. Karlsson,Nicholas Mitsios,Csaba Adori,Per Oksvold,Fredrik Edfors,Agnieszka Limiszewska,Feria Hikmet,Jinrong Huang,Yutao Du,Lin Lin,Zhanying Dong,Ling Yang,Xin Liu,Hui Jiang,Xun Xu,Jian Wang,Huanming Yang,Lars Bolund,Adil Mardinoglu,Cheng Zhang,Kalle von Feilitzen,Cecilia Lindskog,Fredrik Pontén,Yonglun Luo,Tomas Hökfelt,Mathias Uhlén,Mathias Uhlén,Jan Mulder +31 more
TL;DR: A comprehensive molecular dissection of the main regions of the human, pig, and mouse brain using transcriptomics and antibody-based mapping suggests similar regional organization and expression patterns in the three mammalian species, consistent with the view that basic brain architecture is preserved during mammalian evolution.