E
Eytan Domany
Researcher at Weizmann Institute of Science
Publications - 335
Citations - 22170
Eytan Domany is an academic researcher from Weizmann Institute of Science. The author has contributed to research in topics: Gene & Ising model. The author has an hindex of 70, co-authored 333 publications receiving 20941 citations. Previous affiliations of Eytan Domany include Ben-Gurion University of the Negev & University of Washington.
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Journal ArticleDOI
Genome-wide midrange transcription profiles reveal expression level relationships in human tissue specification
Itai Yanai,Hila Benjamin,Michael Shmoish,Vered Chalifa-Caspi,Maxim Shklar,Ron Ophir,Arren Bar-Even,Shirley Horn-Saban,Marilyn Safran,Eytan Domany,Doron Lancet,Orit Shmueli +11 more
TL;DR: The analyses provide a novel route to infer expression profiles for presumed ancestral nodes in the tissue dendrogram, whereby de novo enhancement and diminution of gene expression go hand in hand, and highlight the importance of gene suppression events.
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Coupled two-way clustering analysis of gene microarray data
TL;DR: An algorithm, based on iterative clustering, that performs an algorithm to identify subsets of the genes and samples, such that when one of these is used to cluster the other, stable and significant partitions emerge.
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Outcome signature genes in breast cancer: is there a unique set?
TL;DR: It is shown that the resulting set of genes is not unique; it is strongly influenced by the subset of patients used for gene selection, and the correlations fluctuate strongly when measured over different subsets of patients.
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Thousands of samples are needed to generate a robust gene list for predicting outcome in cancer
Liat Ein-Dor,Or Zuk,Eytan Domany +2 more
TL;DR: A previously undescribed mathematical method is introduced, probably approximately correct (PAC) sorting, for evaluating the robustness of reported predictive gene lists, and for several published data sets the number of samples that are needed to achieve any desired level of reproducibility.
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Stem Cell–Related “Self-Renewal” Signature and High Epidermal Growth Factor Receptor Expression Associated With Resistance to Concomitant Chemoradiotherapy in Glioblastoma
Anastasia Murat,Eugenia Migliavacca,Thierry Gorlia,Wanyu L. Lambiv,Tal Shay,Marie-France Hamou,Nicolas de Tribolet,Luca Regli,Wolfgang Wick,Mathilde C.M. Kouwenhoven,Johannes A. Hainfellner,Frank L. Heppner,Pierre-Yves Dietrich,Yitzhak Zimmer,J. Gregory Cairncross,Robert-Charles Janzer,Eytan Domany,Mauro Delorenzi,Roger Stupp,Monika E. Hegi +19 more
TL;DR: This study provides first clinical evidence for the implication of a "glioma stem cell" or "self-renewal" phenotype in treatment resistance of glioblastoma.