F
Fang Chen
Researcher at University of Technology, Sydney
Publications - 587
Citations - 15372
Fang Chen is an academic researcher from University of Technology, Sydney. The author has contributed to research in topics: Computer science & Cognitive load. The author has an hindex of 46, co-authored 515 publications receiving 11746 citations. Previous affiliations of Fang Chen include George Mason University & University of Sydney.
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Journal ArticleDOI
Sequencing of 50 Human Exomes Reveals Adaptation to High Altitude
Xin Yi,Yu Liang,Emilia Huerta-Sanchez,Xin Jin,Zha Xi Ping Cuo,John E. Pool,John E. Pool,Xun Xu,Hui Jiang,Nicolas Vinckenbosch,Thorfinn Sand Korneliussen,Hancheng Zheng,Tao Liu,Weiming He,Kui Li,Ruibang Luo,Xifang Nie,Honglong Wu,Meiru Zhao,Hongzhi Cao,Jing Zou,Ying Shan,Shuzheng Li,Qi Yang,Asan,Peixiang Ni,Geng Tian,Junming Xu,Xiao Liu,Tao Jiang,Renhua Wu,Guangyu Zhou,Meifang Tang,Junjie Qin,Tong Wang,Shuijian Feng,Guohong Li,Huasang,Jiangbai Luosang,Wei Wang,Fang Chen,Yading Wang,Xiaoguang Zheng,Zhuo Li,Zhuoma Bianba,Ge Yang,Xiznping Wang,Shuhui Tang,Guoyi Gao,Yong Chen,Zhen Luo,Lamu Gusang,Zheng Cao,Qinghui Zhang,Wei-Han OuYang,Xiaoli Ren,Huiqing Liang,Huisong Zheng,Yebo Huang,Jingxiang Li,Lars Bolund,Karsten Kristiansen,Yingrui Li,Yong Zhang,Xiuqing Zhang,Ruiqiang Li,Songgang Li,Huanming Yang,Rasmus Nielsen,Rasmus Nielsen,Jun Wang,Jing Wang +71 more
TL;DR: A population genomic survey has revealed a functionally important locus in genetic adaptation to high altitude, and the strongest signal of natural selection came from endothelial Per-Arnt-Sim domain protein 1 (EPAS1), a transcription factor involved in response to hypoxia.
Journal ArticleDOI
The diploid genome sequence of an Asian individual.
Jun Wang,Wei Wang,Ruiqiang Li,Ruiqiang Li,Yingrui Li,Yingrui Li,Yingrui Li,Geng Tian,Geng Tian,Laurie Goodman,Wei Fan,Junqing Zhang,Jun Li,Juanbin Zhang,Yiran Guo,Yiran Guo,Binxiao Feng,Heng Li,Heng Li,Yao Lu,Xiaodong Fang,Huiqing Liang,Zhenglin Du,Dong Li,Yiqing Zhao,Yiqing Zhao,Yujie Hu,Yujie Hu,Zhenzhen Yang,Hancheng Zheng,Ines Hellmann,Michael Inouye,John E. Pool,Xin Yi,Xin Yi,Jing Zhao,Jinjie Duan,Yan Zhou,Junjie Qin,Junjie Qin,Lijia Ma,Lijia Ma,Guoqing Li,Zhentao Yang,Guojie Zhang,Guojie Zhang,Bin Yang,Chang Yu,Fang Liang,Fang Liang,Wenjie Li,Shaochuan Li,Dawei Li,Peixiang Ni,Jue Ruan,Jue Ruan,Qibin Li,Qibin Li,Hongmei Zhu,Dongyuan Liu,Zhike Lu,Ning Li,Ning Li,Guangwu Guo,Guangwu Guo,Jianguo Zhang,Jia Ye,Lin Fang,Qin Hao,Qin Hao,Quan Chen,Quan Chen,Yu Liang,Yu Liang,Yeyang Su,Yeyang Su,A. san,A. san,Cuo Ping,Cuo Ping,Shuang Yang,Fang Chen,Fang Chen,Li Li,Ke Zhou,Hongkun Zheng,Hongkun Zheng,Yuanyuan Ren,Ling Yang,Yang Gao,Yang Gao,Guohua Yang,Guohua Yang,Zhuo Li,Xiaoli Feng,Karsten Kristiansen,Gane Ka-Shu Wong,Gane Ka-Shu Wong,Rasmus Nielsen,Richard Durbin,Lars Bolund,Lars Bolund,Xiuqing Zhang,Xiuqing Zhang,Songgang Li,Songgang Li,Songgang Li,Huanming Yang,Huanming Yang,Jian Wang,Jian Wang +110 more
TL;DR: Genotyping analysis showed that SNP identification had high accuracy and consistency, indicating the high sequence quality of this assembly, and the potential usefulness of next-generation sequencing technologies for personal genomics.
Journal ArticleDOI
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.
Louise Bowman,Marion Mafham,K Wallendszus,William M. Stevens,Georgina Buck,Jill Barton,Kevin T. Murphy,Theingi Aung,Richard Haynes,Jolyon Cox,Aleksandra Murawska,Allen Young,Michael Lay,Fang Chen,Emily L. Sammons,Emma Waters,Amanda I Adler,Jonathan Bodansky,Andrew Farmer,Roger McPherson,Andrew Neil,David Simpson,Richard Peto,Colin Baigent,Rory Collins,Sarah Parish,Jane Armitage +26 more
TL;DR: Aspirin use prevented serious vascular events in persons who had diabetes and no evident cardiovascular disease at trial entry, but it also caused major bleeding events.
Journal ArticleDOI
Effects of Anacetrapib in Patients with Atherosclerotic Vascular Disease
Hps,Louise Bowman,Jemma C. Hopewell,Fang Chen,K Wallendszus,William M. Stevens,Rory Collins,Rory Collins,Stephen D. Wiviott,Stephen D. Wiviott,Christopher P. Cannon,Christopher P. Cannon,Eugene Braunwald,Emily L. Sammons,Martin J Landray +14 more
TL;DR: Among patients with atherosclerotic vascular disease who were receiving intensive statin therapy, the use of anacetrapib resulted in a lower incidence of major coronary events than the use in the placebo group.
Journal ArticleDOI
HPS2-THRIVE randomized placebo-controlled trial in 25 673 high-risk patients of ER niacin/laropiprant: trial design, pre-specified muscle and liver outcomes, and reasons for stopping study treatment
Richard Haynes,L. Jiang,Jemma C. Hopewell,Jing Li,Fang Chen,Sarah Parish,Martin J Landray,Rory Collins,Jane Armitage,Colin Baigent,Zhengming Chen,Yiping Chen,Terje R. Pedersen,Michael Hill +13 more
TL;DR: The risk of myopathy was increased by adding ERN/LRPT to simvastatin 40 mg daily (with or without ezetimibe), particularly in Chinese patients whose myopathy rates on simvastsatin were higher.