Author
Fang Yang
Bio: Fang Yang is an academic researcher. The author has contributed to research in topics: Ionic liquid & Aldehyde. The author has an hindex of 4, co-authored 7 publications receiving 79 citations.
Topics: Ionic liquid, Aldehyde, Ring (chemistry), Bromide, Quinoline
Papers
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TL;DR: A series of pyrimido derivatives were synthesized via the three-component reaction of an aldehyde, 6-aminopyrimidine-2,4-dione and 5,5-dimethyl-1,3-cyclohexanedione or 1,3indanedione in ionic liquid 1-n-butyl-3-methylimidazolium bromide ([bmim]Br).
59 citations
TL;DR: In this paper, a series of new 3,3′-benzylidenebis(4-hydroxy-6-methylpyridin-2(1H)-one) derivatives were synthesized via a three-component reaction of an aldehyde, an aniline or ammonium acetate and 6-methyl-4hydroxypyran-2-one in ionic liquid.
18 citations
TL;DR: Three novel and simple N,N′-diacylhydrazine-based colorimetric receptors have been prepared and results indicated that a 1:1 stoichiometry complex was formed between the receptors and the anions, while 1H NMR titrations confirmed hydrogen binding interaction.
Abstract: Three novel and simple N,N′-diacylhydrazine-based colorimetric receptors have been prepared. The binding properties of the receptors to anions such as F−, Cl−, Br−, AcO−, HSO4− and H2PO4− in acetonitrile solution were examined by UV-Vis spectroscopy methods, which show high sensitivity and selectivity to F− and AcO− over other anions. The results indicated that a 1:1 stoichiometry complex was formed between the receptors and the anions, while 1H NMR titrations confirmed hydrogen binding interaction between the receptors and the anions.
6 citations
TL;DR: In this paper, the title compounds 3,3,6,6-tetramethyl-9-(2,4-dichlorophenyl)-3,4, 6,7,9,10-hexahydro-2H,5H-acridine-1,8-dione 1 (C23H25Cl2NO2, Mr = 418.34) and 3.3, 6.6.6
Abstract: The title compounds 3,3,6,6-tetramethyl-9-(2,4-dichlorophenyl)-3,4,6,7,9,10-hexahydro-2H,5H-acridine-1,8-dione 1 (C23H25Cl2NO2, Mr = 418.34) and 3,3,6,6-tetramethyl-9,10-di(4-methoxy-phenyl)-3,4,6,7,9,10-hexahydro-2H,5H-acridine-1,8-dione 2 (C31H35NO4, Mr = 485.60) were synthesized and crystallized. The crystals of compound 1 are monoclinic, space group P21/c, a = 9.826(3), b = 19.866(5), c = 11.471(3) A, β = 111.929(4)°, Z = 4, V = 2077(1) A3; The compound 2 crystallizes in space group P21/c, with cell parameters a = 12.089(2), b = 11.447(2), c = 19.742(3) A, β = 101.00(1)°, V = 2681.8(8) A3 and Dcalc = 1.203 g/cm3 for Z = 4. X-ray analysis reveals that atoms C(1), C(6), C(7), C(8), C(13) and N(1) form a 1,4-dihydropyridine ring in compound 1, which adopts half-chair conformation. In compound 2 the atoms C(1), C(6), C(7), C(8), C(13) and N form a 1,4-dihydropyridine ring which adopts boat conformation. In addition, the two outer six-membered rings display half-chair conformations in the crystal structures 1 and 2.
5 citations
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386 citations
TL;DR: The aim of this tutorial review is to highlight the synergistic effect of the combined use of MCRs and ILs for the development of new eco-compatible methodologies for heterocyclic chemistry.
Abstract: The efficiency of a chemical synthesis can be nowadays measured, not only by parameters like selectivity and overall yield, but also by its raw material, time, human resources and energy requirements, as well as the toxicity and hazard of the chemicals and the protocols involved. The development of multicomponent reactions (MCRs) in the presence of task-specific ionic liquids (ILs), used not only as environmentally benign reaction media, but also as catalysts, is a new approach that meet with the requirements of sustainable chemistry. The aim of this tutorial review is to highlight the synergistic effect of the combined use of MCRs and ILs for the development of new eco-compatible methodologies for heterocyclic chemistry.
369 citations
TL;DR: Recent advances on multicomponent domino reactions for the construction of five-, six-, and seven-membered heterocyclic skeletons and their multicyclic derivatives are covered.
Abstract: Multicomponent domino reactions (MDRs) serve as a rapid and efficient tool for the synthesis of versatile heterocycles, particularly those containing structural diversity and complexity, by a one-pot operation. These reactions can dramatically reduce the generation of chemical wastes, costs of starting materials, and the use of energy and manpower. Moreover, the reaction period can be substantially shortened. This Review covers recent advances on multicomponent domino reactions for the construction of five-, six-, and seven-membered heterocyclic skeletons and their multicyclic derivatives.
355 citations
TL;DR: The magnetic nanoparticles supported silica sulfuric acid was used as an efficient catalyst for the synthesis of pyrimido[4,5-b]quinolines and indeno fused pyrido[2,3-d]pyrimidines in water as mentioned in this paper.
92 citations
TL;DR: An efficient one-pot synthesis of fused pyridine derivatives by three-component reaction of aldehyde, acyl acetonitrile, and electron-rich amino heterocycles (including aminopyrazole and aminouracils) in ionic liquid is reported.
Abstract: An efficient one-pot synthesis of fused pyridine derivatives (including pyrazolo[3,4-b]pyridine and pyrido[2,3-d]pyrimidine) by three-component reaction of aldehyde, acyl acetonitrile, and electron-rich amino heterocycles (including aminopyrazole and aminouracils) in ionic liquid is reported. This new protocol has the advantages of environmental friendliness, higher yields, shorter reaction times, and convenient operation.
80 citations