F
Farhadul Islam
Researcher at University of Rajshahi
Publications - 89
Citations - 1782
Farhadul Islam is an academic researcher from University of Rajshahi. The author has contributed to research in topics: Cancer & Colorectal cancer. The author has an hindex of 22, co-authored 75 publications receiving 1282 citations. Previous affiliations of Farhadul Islam include Griffith University & University of Queensland.
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Cancer stem cell: fundamental experimental pathological concepts and updates.
TL;DR: The cancer stem cell hypothesis originated in the late nineteenth century and the existence of haematopoietic stem cells was demonstrated a century later, demonstrating that the concept was possible.
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Translational potential of cancer stem cells: A review of the detection of cancer stem cells and their roles in cancer recurrence and cancer treatment.
TL;DR: Given their significance in cancer biology, refining the isolation and targeting of CSCs will play an important role in future management of cancer.
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The Roles of Cancer Stem Cells and Therapy Resistance in Colorectal Carcinoma.
TL;DR: To conclude, the understanding of these mechanisms of CSC in CRC could lead to the improved management of patients with CRC and deep understanding and concerted research are necessary to design novel therapies targeting CSCs.
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The Identifications and Clinical Implications of Cancer Stem Cells in Colorectal Cancer
TL;DR: Novel potential therapeutic strategies, such as development of monoclonal antibodies or immunotoxins and targeting various cell surface molecules in colorectal CSCs and/or components of signaling pathways, have been developed, which could open new opportunities for the better management of patients with coloreCTal carcinoma.
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Genetic alterations in Krebs cycle and its impact on cancer pathogenesis.
TL;DR: In this paper, mutations in genes encoding aconitase, isocitrate dehydrogenase, succinate dehydrogenases, fumarate hydratase, and citrate synthase are noted in many cancers.