F
Farshid Noorbakhsh
Researcher at Tehran University of Medical Sciences
Publications - 118
Citations - 3787
Farshid Noorbakhsh is an academic researcher from Tehran University of Medical Sciences. The author has contributed to research in topics: Experimental autoimmune encephalomyelitis & Neuroinflammation. The author has an hindex of 29, co-authored 108 publications receiving 3116 citations. Previous affiliations of Farshid Noorbakhsh include University of Alberta & University of Calgary.
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Journal ArticleDOI
A1 Adenosine Receptor Upregulation and Activation Attenuates Neuroinflammation and Demyelination in a Model of Multiple Sclerosis
Shigeki Tsutsui,Jurgen Schnermann,Farshid Noorbakhsh,Scot D. Henry,V. Wee Yong,Brent W. Winston,Kenneth G. Warren,Christopher Power +7 more
TL;DR: Modulation of neuroinflammation by the A1AR represents a novel mechanism that provides new therapeutic opportunities for MS and other demyelinating diseases.
Journal ArticleDOI
Targeting proteinase-activated receptors: therapeutic potential and challenges
Rithwik Ramachandran,Farshid Noorbakhsh,Farshid Noorbakhsh,Kathryn DeFea,Morley D. Hollenberg +4 more
TL;DR: The mechanisms by which PARs modulate cell function and the roles they can have in physiology and diseases are summarized and an overview of possible strategies for developing PAR antagonists is provided.
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Impaired neurosteroid synthesis in multiple sclerosis
Farshid Noorbakhsh,Kristofor K. Ellestad,Ferdinand Maingat,Kenneth G. Warren,May H. Han,Lawrence Steinman,Glen B. Baker,Christopher Power +7 more
TL;DR: These multi-platform studies point to impaired neurosteroidogenesis in both multiple sclerosis and experimental autoimmune encephalomyelitis, and indicate that allopregnanolone and perhaps other neurosteroids-like compounds might represent potential biomarkers or therapies for multiple sclerosis.
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Proteinase-activated receptor 2 modulates neuroinflammation in experimental autoimmune encephalomyelitis and multiple sclerosis
Farshid Noorbakhsh,Shigeki Tsutsui,Nathalie Vergnolle,Leonie A. Boven,Neda Shariat,Mohammed Vodjgani,Kenneth G. Warren,Patricia Andrade-Gordon,Morley D. Hollenberg,Christopher Power +9 more
TL;DR: Findings reveal previously unreported pathogenic interactions between CNS PAR2 expression and neuroinflammation with ensuing demyelination and axonal injury.
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CD73 specific siRNA loaded chitosan lactate nanoparticles potentiate the antitumor effect of a dendritic cell vaccine in 4T1 breast cancer bearing mice
Farhad Jadidi-Niaragh,Fatemeh Atyabi,Ali Rastegari,Nasim Kheshtchin,Samaneh Arab,Hadi Hassannia,Maryam Ajami,Zahra Mirsanei,Sima Habibi,Farimah Masoumi,Farshid Noorbakhsh,Fazel Shokri,Jamshid Hadjati +12 more
TL;DR: The findings indicate that the use of CD73‐specific siRNA‐loaded NPs provides an immune potentiating function, thereby improves the efficacy of DC based cancer immunotherapy.