Fatih Mehmet Emen

Bio: Fatih Mehmet Emen is an academic researcher from Kırklareli University. The author has contributed to research in topics: Thio- & Thermoluminescence. The author has an hindex of 7, co-authored 12 publications receiving 175 citations. Previous affiliations of Fatih Mehmet Emen include Mersin University.

Theoretical and experimental studies on N-(6-methylpyridin-2-yl-carbamothioyl)biphenyl-4-carboxamide

Abstract: A novel thiourea derivative, N -(6-methylpyridin-2-yl-carbamothioyl)biphenyl-4-carbox amide, is synthesized and characterized by elemental analysis, FT-IR, NMR and single crystal X-ray diffraction study. There are two independent molecules A and B in the asymmetric unit. The short bond lengths of the C-N bonds in the central thiourea fragment indicate partial double bond character in this fragment of the title compound. These results can be explained by the existence of resonance in this part of the molecule. Each A and B molecule is stabilized with an intramolecular N-H•••O hydrogen bond which results in the formation of a pseudo six membered ring. In addition, the independent molecules are linked into a chain along the c axis by weak N-H•••S intermolecular hydrogen bonds. The conformational behavior and structural stability of the optimized geometry of the title compound were also investigated by utilizing ab- initio calculations with 6-31G* basis set at HF, BLYP, and B3LYP levels. The calculated parameters are in good agreement with the corresponding X-ray diffraction values.

4-Chloro-N-[N-(6-methyl-2-pyrid-yl)car-bamo-thio-yl]benzamide.

Abstract: In the title compound, C14H12ClN3OS, the short exocyclic N—C bond lengths indicate resonance in the thiourea part of the mol­ecule. The title compound is stabilized by an intra­molecular N—H⋯N hydrogen bond, which results in the formation of a six-membered ring. In addition, it shows a synperiplanar conformation between the thio­carbonyl group and the pyridine group. Inter­molecular N—H⋯S and C—H⋯O inter­actions are also present.

Synthesis, characterization and luminescence properties of long afterglow Phosphor Ba4Al14O25:Eu,Dy

Abstract: Long persistent afterglow phosphor, Ba4Al14O25:Eu2+,Dy3+ was prepared at high temperature by a solid state reaction in a weak reductive atmosphere. The crystal structure of Ba4Al14O25:Eu2+,Dy3+ has been determined as an orthorhombic Pmmm space group with a=18.200(6) A, b=16.923(6) A, c=5.131(21) A, V=1580.3(9) A3 and Z=8. The reflectance measurement was obtained by using the Diffuse Reflectance Spectrophotometer and the band gap energy of the undoped host phase of Ba4Al14O25 was calculated by using Kubelka-Munk treatment on the diffuse reflectance spectra, and found to be 4.72 eV. The excitation and emission peaks are broad bands and the main emission peak at 520 nm with shoulder at 496 nm belongs to the intrinsic defect of the host and 4f65d1→4f7 transition of Eu2+, respectively. The afterglow decay curve implied that this phosphor contains fast and slow-decay processes. The thermoluminescence glow curve showed one dominant glow peak observed at 50 oC and two weak glow peaks at around 140 oC and 220 oC which are related to the defects at different trap depths.

Thermal analysis of cis-(dithiocyanato)(1,10-phenanthroline-5,6-dione)(4,4′-dicarboxy-2,2′-bipyridyl)ruthenium(II) photosensitizer

Abstract: Thermal behavior of [cis-(dithiocyanato)(1,10-phenanthroline-5,6-dione)(4,4′-dicarboxy-2,2′-bipyridyl)ruthenium(II)], cis-[Ru(L1)(L2)(NCS)2] (where the ligands were L1 = 1,10-Phenanthroline-5,6-dione, L2 = 4,4′-dicarboxy-2,2′-bipyridyl) was investigated by DTA/TG/DTG measurements under inert atmosphere in the temperature range of 298–1473 K as well as by XRD analysis of the final product. After making detailed analysis and comparison of thermogravimetrical and MS measurements of ruthenium complex, the decomposition mechanism of that complex was suggested. The values of activation energy and reaction order of the thermal decompositions were calculated by Ozawa Non-isothermal Method for all decomposition stages. The calculated activation energies vary in between 32 and 49 kJ mol−1.

The cell death pathway induced by metal halide complexes of pyridine and derivative ligands in hepatocellular carcinoma cells - necrosis or apoptosis?

Abstract: Background Drugs designed to restore programmed cell death might be effective against many cancer. It was aimed to study the possible apoptotic-necrotic effects of the pyridinehalide complexes such as dichlorodipyridinepalla-dium(ll) (PdCl2L1(2)), dichlorodipyridinenickel(ll) (NiCl2L1(2)), dichlorodipyridinecopper(ll) (CuCl2L1(2)), dibromodipyridinecopper(ll) (CuBr2L1(2)) and dichlorobis-(2,4-dimethylpyridine)copper(ll) (CuCl2L2(2)) in the hepatocarcinoma cells (Hep G2). Methods All complexes were characterized by elemental analysis, 1H-NMR, FT-IR and Far-IR spectroscopy. Apoptotic effects were evaluated by cell viability assay, DNA laddering assay, LDH assay, DAPI nuclear staining and caspase 1-3-9 activity analysis. Results According to cell proliferation/viability datas, CuCl2L2(2) was estimated the most toxic, NiCl2L1(2) the least toxic complex. Treatment of CuCl2L2(2) in IC50 doses resulted in a remarkable increase lactate dehydrogenase, it was followed by CuBr2L1(2) complex. Picnotic nuclei, anisonucleosis and nuclear condensations in 200 microM concentration of CuCl2L2(2) and CuCl2L1(2) treated cells were observed with DAPI staining also DNA brakes were also determined with electrophoresis. Caspase 1,3 and 9 increased activation were not detected. Conclusions The present study results indicate that, PdCl2L1(2), NiCl2L1(2), CuCl2L1(2), CuBr2L1(2), CuC12L2(2) complexes have antiproliferative action on hepatocellular carcinoma cells. However it would be wrong to interpret this effect as an apoptosis or necrosis exactly.

Theoretical and experimental studies on N-(6-methylpyridin-2-yl-carbamothioyl)biphenyl-4-carboxamide

Abstract: A novel thiourea derivative, N -(6-methylpyridin-2-yl-carbamothioyl)biphenyl-4-carbox amide, is synthesized and characterized by elemental analysis, FT-IR, NMR and single crystal X-ray diffraction study. There are two independent molecules A and B in the asymmetric unit. The short bond lengths of the C-N bonds in the central thiourea fragment indicate partial double bond character in this fragment of the title compound. These results can be explained by the existence of resonance in this part of the molecule. Each A and B molecule is stabilized with an intramolecular N-H•••O hydrogen bond which results in the formation of a pseudo six membered ring. In addition, the independent molecules are linked into a chain along the c axis by weak N-H•••S intermolecular hydrogen bonds. The conformational behavior and structural stability of the optimized geometry of the title compound were also investigated by utilizing ab- initio calculations with 6-31G* basis set at HF, BLYP, and B3LYP levels. The calculated parameters are in good agreement with the corresponding X-ray diffraction values.

Intermolecular interactions in crystalline 1-(adamantane-1-carbonyl)-3-substituted thioureas with Hirshfeld surface analysis

Abstract: The conformationally congested species 1-(adamantane-1-carbonyl)-3-(2,4,6-trimethylphenyl)thiourea has been prepared and fully characterized by elemental analyses, FTIR, 1H NMR, 13C NMR and mass spectrometry. Its crystal structure was determined by single-crystal X-ray diffraction. The dihedral angle between the plane of the 2,4,6-trimethylphenyl group and the plane of the thiourea fragment was optimized by theoretical calculations applying the B3LYP/6-311++G(d,p) level for the purpose of investigating the conformational effects on the stabilization of the crystal packing. A detailed analysis of the intermolecular interactions in a series of six closely related phenylthiourea species bearing the 1-(adamantane-1-carbonyl) group has been performed based on the Hirshfeld surfaces and their associated two-dimensional fingerprint plots. The relative contributions of the main intermolecular contacts as well as the enrichment ratios derived from the Hirshfeld surface analysis establish the 1-acyl thiourea synthon to be a widespread contributor.