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Felice Senatore

Other affiliations: University of Basilicata
Bio: Felice Senatore is an academic researcher from University of Naples Federico II. The author has contributed to research in topics: Essential oil & MF59. The author has an hindex of 21, co-authored 23 publications receiving 2891 citations. Previous affiliations of Felice Senatore include University of Basilicata.

Papers
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TL;DR: Antibacterial activity was particularly high against the genera Clavibacter, Curtobacterium, Rhodococcus, Erwinia, Xanthomonas, Ralstonia, and Agrobacteria, which are responsible for plant or cultivated mushroom diseases worldwide.
Abstract: Essential oils extracted by hydrodistillation from fruits of Cuminum cyminum L. and Carum carvi L. were analyzed by gas chromatography (GC) and GC-mass spectrometry (MS). The main components of C. cyminum oil were p-mentha-1,4-dien-7-al, cumin aldehyde, γ-terpinene, and β-pinene, while those of the C. carvi oil were carvone, limonene, germacrene D, and trans-dihydrocarvone. Antibacterial activity, determined with the agar diffusion method, was observed against Gram-positive and Gram-negative bacterial species in this study. The activity was particularly high against the genera Clavibacter, Curtobacterium, Rhodococcus, Erwinia, Xanthomonas, Ralstonia, and Agrobacterium, which are responsible for plant or cultivated mushroom diseases worldwide. In general, a lower activity was observed against bacteria belonging to the genus Pseudomonas. These results suggest the potential use of the above essential oils for the control of bacterial diseases. Keywords: Cuminum cyminum L.; Carum carvi L.; Apiaceae; plant ext...

462 citations

Journal ArticleDOI
TL;DR: The significant antibacterial activity of essential oils to the bacterial pathogens of mushrooms appears promising and may be useful natural bactericides for the control of bacterial diseases of plants and for seed treatment, in particular in organic agriculture.
Abstract: Essential oils were extracted from the fruits of Coriandrum sativum L. and Foeniculum vulgare Miller var. vulgare (Miller) and assayed in vitro for antibacterial activity to Escherichia coli and Bacillus megaterium, bacteria routinely used for comparison in the antimicrobial assays, and 27 phytopathogenic bacterial species and two mycopathogenic ones responsible for cultivated mushroom diseases. A significant antibacterial activity, as determined with the agar diffusion method, was shown by C. sativum essential oil whereas a much reduced effect was observed for F. vulgare var. vulgare oil. C. sativum and F. vulgare var. vulgare essential oils may be useful natural bactericides for the control of bacterial diseases of plants and for seed treatment, in particular, in organic agriculture. The significant antibacterial activity of essential oils to the bacterial pathogens of mushrooms appears promising.

296 citations

Journal ArticleDOI
TL;DR: The essential oil of the Italian thyme Thymus pulegioides growing wild has been extracted by hydrodistillation from leaves and flowers collected at different growth times as mentioned in this paper.
Abstract: Essential oil of the Italian thyme Thymus pulegioides growing wild has been extracted by hydrodistillation from leaves and flowers collected at different growth times. The constituents of the essential oil have been characterized by gas chromatography (GC) and GC−mass spectrometry. Sixty-three compounds have been identified. Essential oils were characterized by a high content of γ-terpinene, p-cymene, thymol, and carvacrol which varied from 57.3 to 62.5% of the total oil content. Essential oil yield and composition vary throughout the vegetation time of the plant. The best time to harvest this species of thyme, for both essential oil yield and phenol content, is during or immediately after the full bloom. Keywords: Thymus pulegioides; essential oil; harvesting time; γ-terpinene; p-cymene; thymol

198 citations

Journal ArticleDOI
TL;DR: The growth-inhibitory and proapoptotic effects of the eighteen sage essential oils were evaluated in three human melanoma cell lines, A375, M14, and A2058, and show that the main components were α-thujone, camphor, borneol, γ-muurolene and sclareol for all the samples, but the percentages varied depending on environmental factors such as altitude, water availability and pedo-climatic conditions.

180 citations

Journal ArticleDOI
06 Aug 1999-Vaccine
TL;DR: The addition of MF59 increased the immunogenicity of the subunit influenza vaccine in elderly persons with low pre-vaccination titres, who are at greatest risk of developing severe influenza disease and vaccine failure, without a clinically important increase in reactogenicity.

179 citations


Cited by
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Journal ArticleDOI
Sara A. Burt1
TL;DR: In vitro studies have demonstrated antibacterial activity of essential oils (EOs) against Listeria monocytogenes, Salmonella typhimurium, Escherichia coli O157:H7, Shigella dysenteria, Bacillus cereus and Staphylococcus aureus at levels between 0.2 and 10 microl ml(-1).

9,091 citations

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TL;DR: Findings suggest that, at least in part, the encountered beneficial effects of essential oils are due to prooxidant effects on the cellular level.

6,174 citations

Journal ArticleDOI
TL;DR: In this paper, the authors proposed to use CO2 for environmentally-benign physical and chemical processing that adds value to the process, using CO2 as an alternate medium or solvent or co-reactant or a combination of them.

1,541 citations

Journal ArticleDOI
TL;DR: The results of this study confirmed the possibility of using thyme essential oils or some of their components in food systems to prevent the growth of foodborne bacteria and extend the shelf‐life of processed foods.
Abstract: Essential oils and their components are becoming increasingly popular as naturally occurring antimicrobial agents. In this work the chemical composition and the antimicrobial properties of Thymus essential oils and of their main components were determined. Three essential oils obtained from different species of Thymus growing wild in Sardinia and a commercial sample of Thymus capitatus oil were analysed. The essential oil components were identified by GC/MS analysis. The antimicrobial activity of the oils and components was determined against a panel of standard reference strains and multiple strains of food-derived spoilage and pathogenic bacteria, using a broth microdilution method. The GC/MS analysis showed that the major constituents of the oils were monoterpene hydrocarbons and phenolic monoterpenes, but the concentration of these compounds varied greatly among the oils examined. The results of the antimicrobial assay showed that essential oils extracted from Sardinian Thymus species have an antimicrobial activity comparable to the one observed in other thyme oils. It seems also confirmed that the antimicrobial properties of thyme essential oils are mainly related to their high phenolic content. Among the single compounds tested carvacrol and thymol turned out to be the most efficient against both reference strains and food-derived bacteria. The results of this study confirmed the possibility of using thyme essential oils or some of their components in food systems to prevent the growth of foodborne bacteria and extend the shelf-life of processed foods.

1,043 citations

Journal ArticleDOI
TL;DR: Supercritical extraction and fractionation of natural matter is one of the early and most studied applications in the field of supercritical fluids in the last 10 years, studies on the extraction of classical compounds like essential and seed oils from various sources, with or without the addition of a co-solvent have been published.
Abstract: Supercritical extraction and fractionation of natural matter is one of the early and most studied applications in the field of supercritical fluids In the last 10 years, studies on the extraction of classical compounds like essential and seed oils from various sources: seeds, fruits, leaves, flowers, rhizomes, etc, with or without the addition of a co-solvent have been published Supercritical extraction of antioxidants, pharmaceuticals, colouring matters, and pesticides has also been studied The separation of liquid mixtures and the antisolvent extraction are other processes that can perform very interesting separations Mathematical modelling has also been developed and refined for some of these processes The objective of this review is to critically analyze traditional and new directions in the research on natural matter separation by supercritical fluids extraction and fractionation

1,003 citations