F
Fernando Ferreira Costa
Researcher at State University of Campinas
Publications - 435
Citations - 10793
Fernando Ferreira Costa is an academic researcher from State University of Campinas. The author has contributed to research in topics: Gene & Sickle cell anemia. The author has an hindex of 45, co-authored 412 publications receiving 9701 citations. Previous affiliations of Fernando Ferreira Costa include Yale University & Federal University of São Paulo.
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Journal ArticleDOI
The genome sequence of the plant pathogen Xylella fastidiosa
Andrew J. G. Simpson,Fernando C. Reinach,Paulo Arruda,F. A. Abreu,Marcio Luis Acencio,R. Alvarenga,Lucia Maria Carareto Alves,Jorge E. Araya,Gilson S. Baia,C. S. Baptista,Mario H. Barros,Eric D. Bonaccorsi,Silvana Bordin,Joseph M. Bové,Marcelo R.S. Briones,M. R.P. Bueno,Anamaria A. Camargo,Luis Eduardo Aranha Camargo,Dirce Maria Carraro,Helaine Carrer,N. B. Colauto,Carlos Augusto Colombo,Fernando Ferreira Costa,M. C. R. Costa,Claudio M. Costa-Neto,Luiz Lehmann Coutinho,M. Cristofani,Emmanuel Dias-Neto,C. Docena,Hamza El-Dorry,Agda Paula Facincani,Ari J. S. Ferreira,V. C.A. Ferreira,Jesus Aparecido Ferro,Jane Silveira Fraga,Suzelei C. França,Marília Caixeta Franco,Marcus Frohme,Luiz Roberto Furlan,M. Garnier,Gustavo H. Goldman,Maria Helena S. Goldman,Suely Lopes Gomes,Arthur Gruber,Paulo L. Ho,Joerg Hoheisel,M.L. Junqueira,Edson L. Kemper,João Paulo Kitajima,José Eduardo Krieger,Eiko E. Kuramae,F. Laigret,Marcio Rodrigues Lambais,Luciana C. C. Leite,Eliana Gertrudes de Macedo Lemos,Manoel Victor Franco Lemos,Silvio A. Lopes,Catalina Romero Lopes,J. A. Machado,Marco Antonio Machado,Alda Maria Backx Noronha Madeira,Humberto Maciel França Madeira,Humberto Maciel França Madeira,Celso Luis Marino,Marilis V. Marques,Elizabeth A. L. Martins,E. M.F. Martins,Adriana Yamaguti Matsukuma,Carlos Frederico Martins Menck,E. C. Miracca,Cristina Yumi Miyaki,Claudia Barros Monteiro-Vitorello,D. H. Moon,Maria Aparecida Nagai,Ana L. T. O. Nascimento,Luis Eduardo Soares Netto,A. Nhani,Francisco G. Nobrega,Francisco G. Nobrega,Luiz R. Nunes,Marcos Antonio de Oliveira,M. C. de Oliveira,R. C. de Oliveira,Darío Abel Palmieri,A. Paris,B. R. Peixoto,Gonçalo A.G. Pereira,H. A. Pereira,João Bosco Pesquero,Ronaldo Bento Quaggio,Patrícia G. Roberto,Vanderlei Rodrigues,Artur J.M. Rosa,V. E. de Rosa,R. G. de Sá,Roberto Vicente Santelli,H. E. Sawasaki,A.C.R. da Silva,A M da Silva,F. R. da Silva,Wilson A. Silva,J. F. da Silveira,M. L.Z. Silvestri,Walter José Siqueira,A. A. de Souza,A. P. de Souza,M. F. Terenzi,Daniela Truffi,Siu Mui Tsai,M. H. Tsuhako,Homero Vallada,M. A. Van Sluys,Sergio Verjovski-Almeida,André Luiz Vettore,Marco Antônio Zago,Mayana Zatz,João Meidanis,João C. Setubal +117 more
TL;DR: The complete genome sequence of X. fastidiosa clone 9a5c is reported, providing direct evidence of phage-mediated horizontal gene transfer and indicating that the molecular basis for bacterial pathogenicity is both conserved and independent of host.
Journal ArticleDOI
Sickle cell disease
Gregory J. Kato,Frédéric B. Piel,Clarice D. Reid,Marilyn H. Gaston,Kwaku Ohene-Frempong,Lakshmanan Krishnamurti,Wally R. Smith,Julie A. Panepinto,David J. Weatherall,Fernando Ferreira Costa,Elliott Vichinsky +10 more
TL;DR: SCD is characterized by a remarkable phenotypic complexity; common acute complications are acute pain events, acute chest syndrome and stroke; chronic complications (including chronic kidney disease) can damage all organs.
Journal ArticleDOI
DNA polymorphisms at the BCL11A, HBS1L-MYB, and β-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease
Guillaume Lettre,Vijay G. Sankaran,Marcos André Cavalcanti Bezerra,Aderson S Araujo,Manuela Uda,Serena Sanna,Antonio Cao,David Schlessinger,Fernando Ferreira Costa,Joel N. Hirschhorn,Stuart H. Orkin +10 more
TL;DR: Genotyping additional BCL11A SNPs, HBS1L-MYB SNPs and an SNP upstream of Gγ-globin (HBG2; the XmnI polymorphism) provided a clear example of inherited common sequence variants modifying the severity of a monogenic disease.
Journal ArticleDOI
Shotgun sequencing of the human transcriptome with ORF expressed sequence tags
Emmanuel Dias Neto,Ricardo G. Correa,Sergio Verjovski-Almeida,Marcelo R.S. Briones,Maria Aparecida Nagai,Wilson da Silva,Marco Antônio Zago,Silvana Bordin,Fernando Ferreira Costa,Gustavo H. Goldman,Alex F. Carvalho,Adriana Yamaguti Matsukuma,Gilson S. Baia,David H. Simpson,Adriana Brunstein,Paulo S. L. Oliveira,Philipp Bucher,C. Victor Jongeneel,Michael J. O'Hare,Fernando Augusto Soares,Ricardo R. Brentani,Luis F.L. Reis,Sandro J. de Souza,Andrew J. G. Simpson +23 more
TL;DR: Theoretical considerations predict that amplification of expressed gene transcripts by reverse transcription-PCR using arbitrarily chosen primers will result in the preferential amplification of the central portion of the transcript, and this approach should make a significant contribution to the early identification of important human genes.
Journal ArticleDOI
The mutation Ala677-->Val in the methylene tetrahydrofolate reductase gene: a risk factor for arterial disease and venous thrombosis.
Valder R. Arruda,P M von Zuben,L C Chiaparini,Joyce M. Annichino-Bizzacchi,Fernando Ferreira Costa +4 more
TL;DR: The hypothesis that being a homozygote for the MTHFR-T is a risk factor for the development of arterial disease and also for venous thrombosis is supported.