Fernando Riveros-Mckay

TL;DR: A genome-wide association analysis in the UK Biobank and INTERVAL studies is performed, providing evidence of shared genetic pathways linking blood cell indices with complex pathologies, including autoimmune diseases, schizophrenia, and coronary heart disease and evidence suggesting previously reported population associations betweenBlood cell indices and cardiovascular disease may be non-causal.

TL;DR: The heritability of thinness is characterised which is comparable to that of severe obesity, although with incomplete genetic overlap, and the ability to replicate loci found with much larger sample sizes demonstrates the value of clinical extremes and suggests that characterisation of the genetics ofthinness may provide a more nuanced understanding of the genetic architecture of body weight regulation.

TL;DR: In this article, genetic data can be used to improve standard cardiovascular disease risk calculators, as the latter are routinely used in clinical practice to diagnose and treat cardiovascular disease in patients.

TL;DR: RNA sequencing of whole olfactory mucosa samples from mouse, rat, dog, marmoset, macaque, and human shows that OSN subtypes, representative of all known mouse chemosensory receptor gene families, are present in all analyzed species and provides insights into the possible functions of highly abundant OSNSubtypes.

TL;DR: This paper proposed ASCVD-IRT, a new integrated risk tool (IRT) which combines ASCVD and polygenic risk scores (PRSs) to predict 10-year risk of ASCVD across diverse ethnicity and ancestry groups.