Filippo Ubaldi

TL;DR: Although there is a great interest in this field, due to the lack of large prospective cohort studies and randomized trials on these topics, the level of evidence is not higher than 3 for most of the recommendations highlighting the need of further research efforts in many areas of this field.

TL;DR: Data show that sperm DNA damage can be efficiently treated with oral antioxidants administered during a relatively short time period.

TL;DR: Oocyte vitrification procedure followed by ICSI is not inferior to fresh insemination procedure, with regard to fertilization and embryo developmental rates and ongoing clinical pregnancy is compatible with this procedure, even with a restricted number of oocytes available for insemination.

TL;DR: In this article, the most frequently available parameters for clinical decision-making in azoospermic patients: (i) presence of at least one single spermatozoon in preliminary semen analysis; (ii) maximum testicular volume; (iii) serum follicle stimulating hormone (FSH); and (iv) presence in the histology of a randomly-taken testicular biopsy.

TL;DR: This study provides knowledge for a better laboratory and clinical management of blastocyst stage PGS cycles suggesting that the commonly used parameters ofblastocyst evaluation are not good enough indicators to improve the selection among euploid embryos.