F
Flemming Scheutz
Researcher at Statens Serum Institut
Publications - 124
Citations - 11116
Flemming Scheutz is an academic researcher from Statens Serum Institut. The author has contributed to research in topics: Escherichia coli & Virulence. The author has an hindex of 47, co-authored 121 publications receiving 9818 citations. Previous affiliations of Flemming Scheutz include University of Maryland, Baltimore & Technical University of Denmark.
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Journal ArticleDOI
Food-borne diseases - the challenges of 20 years ago still persist while new ones continue to emerge.
Diane G. Newell,Marion Koopmans,Linda Verhoef,Erwin Duizer,Awa Aidara-Kane,Hein Sprong,Marieke Opsteegh,M. Langelaar,John Threfall,Flemming Scheutz,Joke van der Giessen,Hilde Kruse +11 more
TL;DR: Evidence is presented to indicate that the microbiological safety of food remains a dynamic situation heavily influenced by multiple factors along the food chain from farm to fork.
Journal ArticleDOI
Real-Time Whole-Genome Sequencing for Routine Typing, Surveillance, and Outbreak Detection of Verotoxigenic Escherichia coli
Katrine Grimstrup Joensen,Flemming Scheutz,Ole Lund,Henrik Hasman,Rolf Sommer Kaas,Eva Møller Nielsen,Frank Møller Aarestrup +6 more
TL;DR: A real-time evaluation of WGS for routine typing and surveillance of verocytotoxin-producing Escherichia coli found whole-genome sequencing typing is a superior alternative to conventional typing strategies and may also be applied to typing and Surveillance of other pathogens.
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Origins of the E. coli Strain Causing an Outbreak of Hemolytic–Uremic Syndrome in Germany
David A. Rasko,Dale R. Webster,Jason W. Sahl,Ali Bashir,Nadia Boisen,Flemming Scheutz,Ellen E. Paxinos,Robert Sebra,Chen-Shan Chin,Dimitris Iliopoulos,Aaron Klammer,Paul Peluso,Lawrence Lee,Andrey Kislyuk,James H. Bullard,Andrew Kasarskis,Susanna Wang,John Eid,David R. Rank,Julia C. Redman,Susan R. Steyert,Jakob Frimodt-Møller,Carsten Struve,Andreas Petersen,Karen A. Krogfelt,James P. Nataro,Eric E. Schadt,Matthew K. Waldor +27 more
TL;DR: The findings suggest that horizontal genetic exchange allowed for the emergence of the highly virulent Shiga-toxin-producing enteroaggregative E. coli O104:H4 strain that caused the German outbreak, and highlight the way in which the plasticity of bacterial genomes facilitates the emerged of new pathogens.
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Multicenter Evaluation of a Sequence-Based Protocol for Subtyping Shiga Toxins and Standardizing Stx Nomenclature
Flemming Scheutz,Louise D. Teel,Lothar Beutin,Denis Pierard,Glenn Buvens,Helge Karch,Alexander Mellmann,Alfredo Caprioli,Rosangela Tozzoli,Stefano Morabito,Nancy A. Strockbine,Angela R. Melton-Celsa,Maria A. Sanchez,Søren Persson,Alison D. O'Brien +14 more
TL;DR: Using a consistent schema for nomenclature of the Stx toxins and stx genes by phylogenetic sequence-based relatedness of the holotoxin proteins, a typing approach should obviate the need to bioassay each newly described toxin and that predicts important biological characteristics.
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Rapid and Easy In Silico Serotyping of Escherichia coli Isolates by Use of Whole-Genome Sequencing Data
Katrine Grimstrup Joensen,Katrine Grimstrup Joensen,Anna M. M. Tetzschner,Atsushi Iguchi,Frank Møller Aarestrup,Flemming Scheutz +5 more
TL;DR: SerotypeFinder for WGS-based O and H typing predicted 560 of 569 O types and 504 of 508 H types, consistent with conventional serotyping, making WGS typing a superior alternative to conventional typing strategies.