scispace - formally typeset
F

Francesco Castelli

Researcher at University of Brescia

Publications -  445
Citations -  14884

Francesco Castelli is an academic researcher from University of Brescia. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 51, co-authored 396 publications receiving 11421 citations. Previous affiliations of Francesco Castelli include UNESCO & McGill University Health Centre.

Papers
More filters
Journal ArticleDOI

Genetic mechanisms of critical illness in Covid-19.

Erola Pairo-Castineira, +1449 more
- 04 Mar 2021 - 
TL;DR: The GenOMICC (Genetics Of Mortality In Critical Care) genome-wide association study in 2244 critically ill Covid-19 patients from 208 UK intensive care units is reported, finding evidence in support of a causal link from low expression of IFNAR2, and high expression of TYK2, to life-threatening disease.
Journal ArticleDOI

Comparing SARS-CoV-2 with SARS-CoV and influenza pandemics.

TL;DR: Compared with other epidemic coronaviruses, SARS-CoV-2 causes mild or asymptomatic disease in most cases; however, severe to critical illness occurs in a small proportion of infected individuals, with the highest rate seen in people older than 70 years.
Journal ArticleDOI

Tocilizumab for the treatment of severe COVID-19 pneumonia with hyperinflammatory syndrome and acute respiratory failure: A single center study of 100 patients in Brescia, Italy.

TL;DR: It was showed that COVID-19 pneumonia with ARDS was characterized by HIS, and the response to TCZ was rapid, sustained, and associated with significant clinical improvement.
Journal ArticleDOI

Towards tuberculosis elimination: an action framework for low-incidence countries

Knut Lönnroth, +72 more
TL;DR: An action framework for countries with low tuberculosis (TB) incidence sets out priority interventions required for these countries to progress first towards “pre-elimination” and eventually the elimination of TB as a public health problem.