Francesco Regazzoni

Bio: Francesco Regazzoni is an academic researcher from Polytechnic University of Milan. The author has contributed to research in topics: Cryptography & Encryption. The author has an hindex of 32, co-authored 174 publications receiving 3387 citations. Previous affiliations of Francesco Regazzoni include Princeton University & Université catholique de Louvain.

Midori: A Block Cipher for Low Energy

Abstract: In the past few years, lightweight cryptography has become a popular research discipline with a number of ciphers and hash functions proposed. The designers' focus has been predominantly to minimize the hardware area, while other goals such as low latency have been addressed rather recently only. However, the optimization goal of low energy for block cipher design has not been explicitly addressed so far. At the same time, it is a crucial measure of goodness for an algorithm. Indeed, a cipher optimized with respect to energy has wide applications, especially in constrained environments running on a tight power/energy budget such as medical implants. This paper presents the block cipher Midorii¾?The name of the cipher is the Japanese translation for the word Green. that is optimized with respect to the energy consumed by the circuit per bt in encryption or decryption operation. We deliberate on the design choices that lead to low energy consumption in an electrical circuit, and try to optimize each component of the circuit as well as its entire architecture for energy. An added motivation is to make both encryption and decryption functionalities available by small tweak in the circuit that would not incur significant area or energy overheads. We propose two energy-efficient block ciphers Midori128i¾?and Midori64i¾?with block sizes equal to 128 and 64 bits respectively. These ciphers have the added property that a circuit that provides both the functionalities of encryption and decryption can be designed with very little overhead in terms of area and energy. We compare our results with other ciphers with similar characteristics: it was found that the energy consumptions ofi¾?Midori64i¾? and Midori128i¾? are by far better when compared ciphers like PRINCE and NOEKEON.

Stealthy dopant-level hardware trojans

Abstract: In recent years, hardware Trojans have drawn the attention of governments and industry as well as the scientific community. One of the main concerns is that integrated circuits, e.g., for military or critical-infrastructure applications, could be maliciously manipulated during the manufacturing process, which often takes place abroad. However, since there have been no reported hardware Trojans in practice yet, little is known about how such a Trojan would look like, and how difficult it would be in practice to implement one. In this paper we propose an extremely stealthy approach for implementing hardware Trojans below the gate level, and we evaluate their impact on the security of the target device. Instead of adding additional circuitry to the target design, we insert our hardware Trojans by changing the dopant polarity of existing transistors. Since the modified circuit appears legitimate on all wiring layers (including all metal and polysilicon), our family of Trojans is resistant to most detection techniques, including fine-grain optical inspection and checking against "golden chips". We demonstrate the effectiveness of our approach by inserting Trojans into two designs -- a digital post-processing derived from Intel's cryptographically secure RNG design used in the Ivy Bridge processors and a side-channel resistant SBox implementation -- and by exploring their detectability and their effects on security.

Fresh re-keying: security against side-channel and fault attacks for low-cost devices

Abstract: The market for RFID technology has grown rapidly over the past few years. Going along with the proliferation of RFID technology is an increasing demand for secure and privacy-preserving applications. In this context, RFID tags need to be protected against physical attacks such as Differential Power Analysis (DPA) and fault attacks. The main obstacles towards secure RFID are the extreme constraints of passive tags in terms of power consumption and silicon area, which makes the integration of countermeasures against physical attacks even more difficult than for other types of embedded systems. In this paper we propose a fresh re-keying scheme that is especially suited for challenge-response protocols such as used to authenticate tags. We evaluate the resistance of our scheme against fault and side-channel analysis, and introduce a simple architecture for VLSI implementation. In addition, we estimate the cost of our scheme in terms of area and execution time for various security/performance trade-offs. Our experimental results show that the proposed re-keying scheme provides better security (and does so at less cost) than state-of-the-art countermeasures.

Compact implementation and performance evaluation of block ciphers in ATtiny devices

Abstract: The design of lightweight block ciphers has been a very active research topic over the last years. However, the lack of comparative source codes generally makes it hard to evaluate the extent to which implementations of different ciphers actually reach their low-cost goals on various platforms. This paper reports on an initiative aiming to relax this issue. First, we provide implementations of 12 block ciphers on an ATMEL AVR ATtiny45 8-bit microcontroller, and make the corresponding source code available on a web page. All implementations are made public under an open-source license. Common interfaces and design goals are followed by all designers to achieve comparable implementation results. Second, we evaluate performance figures of our implementations with respect to different metrics, including energy-consumption measurements and show our improvements compared to existing implementations.

Architecture and applications of a high resolution gated SPAD image sensor

Abstract: We present the architecture and three applications of the largest resolution image sensor based on single-photon avalanche diodes (SPADs) published to date. The sensor, fabricated in a high-voltage CMOS process, has a resolution of 512 × 128 pixels and a pitch of 24 μm. The fill-factor of 5% can be increased to 30% with the use of microlenses. For precise control of the exposure and for time-resolved imaging, we use fast global gating signals to define exposure windows as small as 4 ns. The uniformity of the gate edges location is ∼140 ps (FWHM) over the whole array, while in-pixel digital counting enables frame rates as high as 156 kfps. Currently, our camera is used as a highly sensitive sensor with high temporal resolution, for applications ranging from fluorescence lifetime measurements to fluorescence correlation spectroscopy and generation of true random numbers.

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

Abstract: Summary Background Since December, 2019, Wuhan, China, has experienced an outbreak of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Epidemiological and clinical characteristics of patients with COVID-19 have been reported but risk factors for mortality and a detailed clinical course of illness, including viral shedding, have not been well described. Methods In this retrospective, multicentre cohort study, we included all adult inpatients (≥18 years old) with laboratory-confirmed COVID-19 from Jinyintan Hospital and Wuhan Pulmonary Hospital (Wuhan, China) who had been discharged or had died by Jan 31, 2020. Demographic, clinical, treatment, and laboratory data, including serial samples for viral RNA detection, were extracted from electronic medical records and compared between survivors and non-survivors. We used univariable and multivariable logistic regression methods to explore the risk factors associated with in-hospital death. Findings 191 patients (135 from Jinyintan Hospital and 56 from Wuhan Pulmonary Hospital) were included in this study, of whom 137 were discharged and 54 died in hospital. 91 (48%) patients had a comorbidity, with hypertension being the most common (58 [30%] patients), followed by diabetes (36 [19%] patients) and coronary heart disease (15 [8%] patients). Multivariable regression showed increasing odds of in-hospital death associated with older age (odds ratio 1·10, 95% CI 1·03–1·17, per year increase; p=0·0043), higher Sequential Organ Failure Assessment (SOFA) score (5·65, 2·61–12·23; p Interpretation The potential risk factors of older age, high SOFA score, and d-dimer greater than 1 μg/mL could help clinicians to identify patients with poor prognosis at an early stage. Prolonged viral shedding provides the rationale for a strategy of isolation of infected patients and optimal antiviral interventions in the future. Funding Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences; National Science Grant for Distinguished Young Scholars; National Key Research and Development Program of China; The Beijing Science and Technology Project; and Major Projects of National Science and Technology on New Drug Creation and Development.