F
Francis M. Giardiello
Researcher at Johns Hopkins University School of Medicine
Publications - 235
Citations - 36959
Francis M. Giardiello is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Familial adenomatous polyposis & Colorectal cancer. The author has an hindex of 53, co-authored 228 publications receiving 34619 citations. Previous affiliations of Francis M. Giardiello include Utah State University & Johns Hopkins University.
Papers
More filters
Journal ArticleDOI
Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps, 2008: a joint guideline from the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology.
Bernard Levin,David A. Lieberman,Beth McFarland,Kimberly S. Andrews,Durado Brooks,John H. Bond,Chiranjeev Dash,Francis M. Giardiello,Seth N. Glick,David W. Johnson,C. Daniel Johnson,Theodore R. Levin,Perry J. Pickhardt,Douglas K. Rex,Robert A. Smith,Alan G. Thorson,Sidney J. Winawer +16 more
TL;DR: Clinicians should be prepared to offer patients a choice between a screening test that is effective at both early cancer detection and cancer prevention through the detection and removal of polyps and those that can detect cancer early and also can detect adenomatous polyps.
Journal ArticleDOI
Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas
Charles E. Eberhart,Robert J. Coffey,Aramandla Radhika,Francis M. Giardiello,Suzanne Ferrenbach,Raymond N. DuBois +5 more
TL;DR: COX-2, but not COX-1, gene expression is markedly elevated in most human colorectal cancers compared with accompanying normal mucosa, and COx-2 expression seems to be increased in a subset of adenomas.
Journal ArticleDOI
Colorectal cancer screening: Clinical guidelines and rationale
Sidney J. Winawer,Robert H. Fletcher,L Miller,F. Godlee,M. H. Stolar,Cynthia D. Mulrow,Steven H. Woolf,SN Glick,Theodore G. Ganiats,John H. Bond,Lee S. Rosen,J. G. Zapka,S. J. Olsen,Francis M. Giardiello,J. E. Sisk,R. Van Antwerp,C. Brown-Davis,D. A. Marciniak,Robert J. Mayer +18 more
TL;DR: This guideline report presents the panel’s recommendations with respect to screening and surveillance in people at average risk for CRC and those at increased risk because of a family history of CRC or genetic syndromes or a personal history of adenomatous polyps, inflammatory bowel disease, or curative-intent resection of CRC.
Journal ArticleDOI
Treatment of Colonic and Rectal Adenomas with Sulindac in Familial Adenomatous Polyposis
Francis M. Giardiello,Stanley R. Hamilton,Anne J. Krush,Steven Piantadosi,Linda M. Hylind,Paul Celano,Susan V. Booker,C. Rahj Robinson,G. Johan A. Offerhaus +8 more
TL;DR: Sulindac reduces the number and size of colorectal adenomas in patients with familial adenomatous polyposis, but its effect is incomplete, and it is unlikely to replace colectomy as primary therapy.
Journal ArticleDOI
Guidelines for Colonoscopy Surveillance After Screening and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer
David A. Lieberman,Douglas K. Rex,Sidney J. Winawer,Francis M. Giardiello,David A. Johnson,Theodore R. Levin +5 more
TL;DR: New issues have emerged since the 2006 guideline, including risk of interval CRC, proximal CRC, and the role of serrated polyps in colon carcinogenesis, which suggests that adherence to prior guidelines is poor.