Franco Borgogno

Bio: Franco Borgogno is an academic researcher from University of Turin. The author has contributed to research in topics: Psychoanalytic theory & Intrapsychic. The author has an hindex of 10, co-authored 43 publications receiving 290 citations.

On the Patient's Becoming an Individual: The Importance of the Analyst's Personal Response to a Deprived Patient and Her Dreams

Abstract: What patients mainly want—which Ferenczi noted as early as 1932 in his clinical diary and which Bion later expressed in his Cogitations (1992)—and what some patients need, is to experience how the analyst lives and processes the interpersonal events that lie at the origin of their affective and mental suffering. This is especially true with schizoid patients who were profoundly emotionally deprived in childhood. In this paper, the author investigates this crucial aspect of the intersubjective analytic relationship in his treatment of just such a patient, an extremely silent and inert young woman. Through a detailed examination of clinical material from various stages of her analysis, he explores how the analyst's unconscious emotional response serves as both a tool for comprehension and a key element of environmental facilitation—a “new beginning,” to use Balint's phrase—that may help the patient attain a level of development and emancipation that he or she has never experienced before.

Role-reversal: a somewhat neglected mirror of heritages of the past.

Abstract: Within a clinical–theoretical framework focused on transference–countertransference dynamics, the authors reflect on role-reversal and on the reasons it has been neglected for a long time in literature. This primitive inter- and intra-psychic process, often at the forefront in our practice, will be discussed in its principal aspects (patient's unconscious identification with parents’ psychic culture and concomitant dissociation of the infant part of the self), signaling how the enactment can be an inevitable element which, putting into play the past dissociated object relationships, becomes a source of mutative understanding.

"Coming from afar" and "temporarily becoming the patient without knowing it": two necessary analytic conditions according to Ferenczi's later thought.

Abstract: In this paper the author discusses two points regarding Ferenczi’s views of psychoanalysis. The first concerns the fact that analysts, like their patients, “come from afar” (a concept of Borgogno, 2011). The second, closely linked to the first, has to do with Ferenczi’s belief that psychoanalytical knowledge is not intellectual but visceral, seeing that if analysts are to truly understand their patients they must first “take on” their suffering in such a way as to “become the patient.” The author follows Ferenczi’s progression along these two points through his whole oeuvre, from his first psychoanalytical writings to the Clinical Diary (1932a) of the last year of his life.

Ferenczi's Clinical and Theoretical Conception of Trauma: A Brief Introductory Map

Abstract: In this paper, I am going to limit myself to tracing a map of the principal points in Ferenczi's thinking concerning trauma. Ferenczi's contribution to trauma theory is fundamental, even though up to today—in spite of the recent “Ferenczian Renaissance”—it still remains for many psychoanalysts simply not acknowledged and not considered and, when it is acknowledged and considered, it is frequently misunderstood or reported only in part. Perhaps this is because passages of his theory are extrapolated without knowing his entire clinical theoretical way or because he is quoted through others without the authors having personally read his work. These last ones are typical habits, as we know, to project one's own ideas, especially our prejudices.

The Doctor, His Patient and the Illness

Abstract: may make for difficulty and perhaps the work could be improved by better integration of the chapters. This is not an adverse criticism of the book. It is merely a constructive criticism for the future, for there is no doubt that this work is the most useful book on operative obstetrics today in the English language. It is also the most beautifully produced and one of the most worth-while books on obstetrics in the whole of modern medical literature. E.E.P.

Inhibition of constitutively active Stat3 suppresses proliferation and induces apoptosis in glioblastoma multiforme cells.

Abstract: Glioblastoma multiforme (GBM), the most common and malignant central nervous system tumor in humans, is highly proliferative and resistant to apoptosis. Stat3, a latent transcription factor being activated by aberrant cytokine or growth factor signaling, acts as a suppressor of apoptosis in a number of cancer cells. Here we report that GBM tumors and cell lines contain high levels of constitutively activated Stat3 when compared with normal human astrocytes, white matter, and normal tissue adjacent to tumor. The persistent activation of Stat3 is in part, attributable to an autocrine action of interleukin-6 in the GBM cell line U251. Janus kinase inhibitor AG490 inhibits Stat3 activation with a concomitant reduction in steady-state levels of Bcl-X(L), Bcl-2 and Mcl-1 proteins and induces apoptosis in U251 cells as revealed by Poly (ADP-ribose) polymerase cleavage and Annexin-V staining. Expression of a dominant negative mutant Stat3 protein or treatment with AG490 markedly reduces the proliferation of U251 cells by inhibiting the constitutive activation of Stat3. These results provide evidence that constitutive activation of Stat3 contributes to the pathogenesis of glioblastoma by promoting both proliferation and survival of GBM cells. Therefore, targeting Stat3 signaling may provide a potential therapeutic intervention for GBM.