F
François Lellouche
Researcher at Laval University
Publications - 145
Citations - 5303
François Lellouche is an academic researcher from Laval University. The author has contributed to research in topics: Mechanical ventilation & Randomized controlled trial. The author has an hindex of 32, co-authored 128 publications receiving 4299 citations. Previous affiliations of François Lellouche include University of Paris-Est & French Institute of Health and Medical Research.
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Journal ArticleDOI
Patient-ventilator asynchrony during assisted mechanical ventilation
TL;DR: One-fourth of patients exhibit a high incidence of asynchrony during assisted ventilation, which is associated with a prolonged duration of mechanical ventilation and with excessive levels of ventilatory support.
Journal ArticleDOI
Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery
C. David Mazer,Richard P. Whitlock,Dean Fergusson,Judith Hall,Emilie P. Belley-Côté,Katherine Connolly,Boris Khanykin,Alexander J. Gregory,Étienne de Médicis,Shay McGuinness,Alistair Royse,François Martin Carrier,Paul J Young,Juan Carlos Villar,Hilary P. Grocott,Manfred D. Seeberger,Stephen E. Fremes,François Lellouche,Summer Syed,Kelly Byrne,Sean M. Bagshaw,Nian C. Hwang,Chirag Mehta,Thomas Painter,Colin Royse,Subodh Verma,Gregory M. T. Hare,Ashley Cohen,Kevin E. Thorpe,Peter Jüni,Nadine Shehata +30 more
TL;DR: In patients undergoing cardiac surgery who were at moderate‐to‐high risk for death, a restrictive strategy regarding red‐cell transfusion was noninferior to a liberal strategy with respect to the composite outcome of death from any cause, myocardial infarction, stroke, or new‐onset renal failure with dialysis, with less blood transfused.
Journal ArticleDOI
Physiologic effects of noninvasive ventilation during acute lung injury.
Ervvan L'her,Nicolas Deye,François Lellouche,Solenne Taillé,Alexandre Demoule,Amanda Tarabini Fraticelli,Jordi Mancebo,Laurent Brochard +7 more
TL;DR: It is concluded that, in patients with acute lung injury, noninvasive pressure-support ventilation combined with positive end-expiratory pressure is needed to reduce inspiratory muscle effort and continuous positive airway pressure, in this setting, improves oxygenation but fails to unload the respiratory muscles.
Journal ArticleDOI
High tidal volumes in mechanically ventilated patients increase organ dysfunction after cardiac surgery.
TL;DR: Tidal volumes of more than 10 ml/kg are risk factors for organ failure and prolonged intensive care unit stay after cardiac surgery, and women and obese patients are particularly at risk of being ventilated with injurious tidal volumes.
Journal ArticleDOI
Prevention of Endotracheal Suctioning-induced Alveolar Derecruitment in Acute Lung Injury
Salvatore Maurizio Maggiore,François Lellouche,Jérôme Pigeot,Solenne Taillé,Nicolas Deye,Xavier Durrmeyer,Jean-Christophe Richard,Jordi Mancebo,François Lemaire,Laurent Brochard +9 more
TL;DR: Suctioning-induced lung derecruitment in acute lung injury can be prevented by performing recruitment maneuvers during suctioning and minimized by avoiding disconnection.