Showing papers by "Frank E. Speizer published in 1977"
TL;DR: For a series of 568 married white men aged 30-70 years who died from coronary heart diseases, and a matched sample of living neighbourhood controls, information was collected on a large number of variables, including physical activity, (PA), classified according to the Health Insurance Plan Study criteria.
Abstract: For a series of 568 married white men aged 30-70 years who died from coronary heart diseases, (CHD), and a matched sample of living neighbourhood controls, information was collected on a large number of variables, including physical activity, (PA), classified according to the Health Insurance Plan Study criteria. Increased leisure PA was associated with a decreased risk of coronary death (p less than .001) but there was no association between job activity and coronary deaths. Step-up multiple regression, based on within-pair differences, was used to control for the possible confounding effects of all variables studied. Even when these variables were controlled for there was still a significant association between increased leisure PA and decreased risk of death due to CHD (P less than .001). These data are consistent with the hypothesis that increased leisure PA can contribute to the prevention of death from CHD.
23 citations
TL;DR: Evaluation of death rates from Cirrhosis of the liver in Massachusetts since 1950 indicate a changing pattern suggestive of a substantial increase in the frequency with which cirrhosis is being recorded as the underlying cause of death.
Abstract: Evaluation of death rates from cirrhosis of the liver in Massachusetts since 1950 indicate a changing pattern suggestive of a substantial increase in the frequency with which cirrhosis is being recorded as the underlying cause of death. By comparing the relationship between the frequency with which cirrhosis is mentioned on the death certificate with its occurrence as the underlying cause of death, it would appear that the increase in death rate represents a real change. Additional evidence is presented to indicated that the increase is occuring in the urban center of the state. Males aged 40-49 and females aged 50-59 have shown the greatest changes. In spite of similar changes occuring on the national scene, the increase appears to be substantially greater in Massachusetts. The evaluation of multiple cause of death as mentioned on death certificates can allow for assessment of significant co-factors contributing to a fatal outcome in a disease like cirrhosis of the liver.
23 citations
TL;DR: The exposures of automobile toll booth collectors in the Boston area to selected air contaminants were monitored during the four seasons from 1972 to 1974 and the study supports the need for environmental control for toll booths located at busy highway and tunnels.
Abstract: The exposures of automobile toll booth collectors in the Boston area to selected air contaminants were monitored during the four seasons from 1972 to 1974. The highest carbon monoxide concentrations were found at the in-city toll booths and the highest lead levels at the surburban booths. Biological monitoring for carbon monoxide and lead exposure were closely related to airborne contaminant levels. The study supports the need for environmental control for toll booths located at busy highway and tunnels.
19 citations
Journal Article•
TL;DR: A series of 159 cases of reported hospitalizations for myocardial infarction occurring before menopause and premenopausal controls were selected from a cohort of married female registered nurses 30-55 years of age residing in 11 of the larger states in the U.S.
Abstract: A series of 159 cases of reported hospitalizations for myocardial infarction (MI) occurring before menopause and 3180 premenopausal controls were selected from a cohort of married female registered nurses 30-55 years of age residing in 11 of the larger states in the U.S. Information was collected by mail questionnaire about oral contraceptive (OC) use as well as a large number of other variables. The proportion of current OC users was higher among the cases (13%) than among the controls (8.6%). There was no evidence of association between duration of OC use and hospitalization for MI. After adjusting for the possible confounding effects of other variables using multiple logistic regression analysis the relative risk of hospitalization for MI among current OC users compared with never users was 1.8 (95% confidence limits 1.1-3.0). The consistency of the findings from this case-control study of American women with those from 2 case-control studies of British women and a descriptive study of vital statistical data lends credibility to the belief that the association between current OC use and MI is causal.(Full text)
1 citations
Journal Article•
1 citations