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Frans Bruyninckx
Researcher at Katholieke Universiteit Leuven
Publications - 37
Citations - 11567
Frans Bruyninckx is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Tarlov cyst & Intensive care. The author has an hindex of 14, co-authored 35 publications receiving 11030 citations. Previous affiliations of Frans Bruyninckx include Catholic University of Leuven.
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Journal ArticleDOI
Intensive Insulin Therapy in Critically Ill Patients
Greet Van den Berghe,Pieter Wouters,Frank Weekers,Charles Verwaest,Frans Bruyninckx,Miet Schetz,Dirk Vlasselaers,Patrick Ferdinande,Peter Lauwers,Roger Bouillon +9 more
TL;DR: Intensive insulin therapy to maintain blood glucose at or below 110 mg per deciliter reduces morbidity and mortality among critically ill patients in the surgical intensive care unit.
Journal ArticleDOI
Insulin therapy protects the central and peripheral nervous system of intensive care patients
TL;DR: Preventing even moderate hyperglycemia with insulin during intensive care protected the central and peripheral nervous systems, with clinical consequences such as shortening of intensive care dependency and possibly better long-term rehabilitation.
Journal ArticleDOI
Intensive Insulin Therapy in Mixed Medical/Surgical Intensive Care Units Benefit Versus Harm
Greet Van den Berghe,Alexander Wilmer,Ilse Milants,Pieter Wouters,Bernard Bouckaert,Frans Bruyninckx,Roger Bouillon,Miet Schetz +7 more
TL;DR: It is concluded that IIT reduces mortality of all medical/surgical ICU patients, except those with a prior history of diabetes, and does not cause harm.
Journal ArticleDOI
Impact of Intensive Insulin Therapy on Neuromuscular Complications and Ventilator Dependency in the Medical Intensive Care Unit
Greet Hermans,Alexander Wilmer,Wouter Meersseman,Ilse Milants,Pieter Wouters,Herman Bobbaers,Frans Bruyninckx,Greet Van den Berghe +7 more
TL;DR: In a subset of medical patients in the intensive care unit for at least 7 days, enrolled in a randomized controlled trial of intensive insulin therapy, those assigned tointensive insulin therapy had a reduced incidence of critical illness polyneuropathy/myopathy and were treated with prolonged mechanical ventilation less frequently.
Journal ArticleDOI
Clinical review: Critical illness polyneuropathy and myopathy
TL;DR: A systematic review of the available literature on the optimal approach for preventing CIP/CIM seems warranted, as conflicting evidence concerning the neuromuscular effects of corticosteroids exists.