Franz Wachtler

TL;DR: The findings suggest that further characterization and identification of the BM cells capable of undergoing myogenic differentiation may have an outstanding impact on therapeutic strategies for diseases of skeletal and cardiac muscle.

TL;DR: The findings indicate that mutations in TECTA are responsible for hearing impairment in these families, and implicate a new type of protein in the pathogenesis of hearing impairment.

TL;DR: After dispersing the granular component and the dense fibrillar component by a hypotonic treatment, removal of most chromatin and preparation of resinless sections, fibrillsar centres remained fixed to a nucleoskeleton and are incorporated into a model for rRNA transcription.

TL;DR: This review addresses the problem of understanding nucleolar morphology in terms of nucleolar function by reviewing in situ-cytochemical results that have not led to a generally accepted view on the structure-function correlation for nucleoli.

TL;DR: The distribution of 18S and 28S ribosomal RNA (rRNA) was visualized in interphases and metaphases of non-stimulated and phytohemagglutinin (PHA)-stimulated human lymphocytes with a recently developed non-autoradiographic in situ hybridization method, indicating the occurrence of movements of the NORs within the nucleus, depending on their transcriptional activity.