F
Friedemann Gebhardt
Researcher at Technische Universität München
Publications - 29
Citations - 1246
Friedemann Gebhardt is an academic researcher from Technische Universität München. The author has contributed to research in topics: Cytotoxic T cell & T cell. The author has an hindex of 12, co-authored 29 publications receiving 1143 citations.
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Journal ArticleDOI
MCMV glycoprotein gp40 confers virus resistance to CD8+ T cells and NK cells in vivo.
Astrid Krmpotić,Dirk H. Busch,Ivan Bubić,Friedemann Gebhardt,Hartmut Hengel,Milena Hasan,Anthony A. Scalzo,Ulrich H. Koszinowski,Stipan Jonjić +8 more
TL;DR: In this paper, the susceptibility of certain inbred mouse strains to murine cytomegalovirus (MCMV) is related to their inability to generate a strong natural killer (NK) cell response.
MCMV glycoprotein gp40 confers virus resistance to CD8+ T cells and NK cells in vivo
Astrid Krmpotić,Dirk H. Busch,Ivan Bubić,Friedemann Gebhardt,Hartmut Hengel,Milena Hasan,Anthony A. Scalzo,Ulrich H. Koszinowski,Stipan Jonjić +8 more
TL;DR: It is found that gp40 but not gp48 controls NK cell activation, which means that a single herpesvirus protein has a dual function in inhibiting both the adaptive as well as the innate immune response.
for Efficient Entry of Listeria monocytogenes into the Spleen
Michael Neuenhahn,Kristen M. Kerksiek,Magdalena Nauerth,Michael H. Suhre,Matthias Schiemann,Friedemann Gebhardt,Christian Stemberger,Klaus Panthel,Trinad Chakraborty,Steffen Jung,Hubertus Hochrein,Thomas Brocker,Dirk H. Busch,Ludwig-Maximilians-University Munich +13 more
TL;DR: In this paper, the role of Dendritic cells during infection with Listeria monocytogenes by performing systemicin vivo depletion of these cells was analyzed and it was shown that CD8a may contribute to primary resistance against infection.
Journal ArticleDOI
CD8α+ Dendritic Cells Are Required for Efficient Entry of Listeria monocytogenes into the Spleen
Michael Neuenhahn,Kristen M. Kerksiek,Magdalena Nauerth,Michael H. Suhre,Matthias Schiemann,Friedemann Gebhardt,Christian Stemberger,Klaus Panthel,Samira Schröder,Trinad Chakraborty,Steffen Jung,Hubertus Hochrein,Holger Rüssmann,Thomas Brocker,Dirk H. Busch +14 more
TL;DR: It is shown that CD8alpha(+) DCs were crucial for L. monocytogenes spreading and proliferation in the spleen and appear to play an important role for efficient bacterial entry into theSpleen, which is of relevance for subsequent immune responses.
Journal ArticleDOI
Colonization with third-generation cephalosporin-resistant Enterobacteriaceae on hospital admission: prevalence and risk factors.
Axel Hamprecht,Anna M Rohde,Michael Behnke,Susanne Feihl,Petra Gastmeier,Friedemann Gebhardt,Winfried V. Kern,Johannes K.-M. Knobloch,Alexander Mischnik,Birgit Obermann,Christiane Querbach,Silke Peter,Christian Schneider,Wiebke Schröder,Frank J. Schwab,Evelina Tacconelli,Miriam Wiese-Posselt,Thorsten Wille,Matthias Willmann,Harald Seifert,Janine Zweigner +20 more
TL;DR: The observed prevalence of 9.5% 3GCREB carriage was higher than previously reported and differed significantly among centres, and the treatment of GERD proved to be an independent risk factor for 3 GCREB colonization.